ACR Meeting Abstracts

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  • Abstract Number: 1334 • ACR Convergence 2025

    Cardiac Biomarkers and Prediction of Major Cardiovascular Events in Rheumatoid Arthritis: Results from the ESPOIR Cohort

    manon lesturgie1, Fiona Oudart1, Anne Cauvet2, Virginie Gonzalez2, Bruno Fautrel3, Arnaud Constantin4, Nathalie Rincheval5, Yannick Allanore6 and Jérôme Avouac7, 1INSERM U1016, Paris, France, 2INSERMU1016, Paris, France, 3Sorbonne Université - APHP, Department of Rheumatology, Hôpital Pitié-Salpêtrière, Inserm UMRS 1136-5, PARIS, France, Paris, France, 4Hôpital Pierre-Paul Riquet, CHU Purpan, Toulouse, France, 5Institut de Recherche Clinique EA2415, Université de Montpellier, Département de Statistiques, Montpellier, France, 6Université Paris Cité, Paris, France, 7Hôpital Cochin, AP-HP Centre - Université Paris Cité, Paris, France

    Background/Purpose: Patients with rheumatoid arthritis (RA) experience premature mortality, largely due to cardiovascular (CV) disease. The increased CV risk is due to both the underlying…
  • Abstract Number: 1340 • ACR Convergence 2025

    Does Moderate Alcohol Use Lower Disease Activity Among Patients with Rheumatoid Arthritis?

    Sarah Crisci1, Joshua Baker2, Kevin Kane3, George Reed4, Dimitrios Pappas5 and Joel Kremer6, 1New York University, New York, NY, 2University of Pennsylvania, Philadelphia, PA, 3University of Massachusetts Lowell, Lowell, MA, 4University of Massachusetts Chan Medical School, Worcester, MA, 5CorEvitas, New York, NY, 6The Corrona Research Foundation, Delray Beach, FL

    Background/Purpose: The relationship between alcohol use and disease activity among patients with rheumatoid arthritis (RA) remains controversial. Several studies have concluded that moderate drinking may…
  • Abstract Number: 1273 • ACR Convergence 2025

    Effectiveness of IV Cyclophosphamide and Mycophenolate Mofetil in the Treatment of Pediatric Systemic Lupus Erythematosus with Lupus Nephritis

    adrienne katrin guiang-valerio, University of Santo Tomas Hospital, Mandaluyong, National Capital Region, Philippines

    Background/Purpose: Lupus nephritis (LN) is more common in children (occurs in 50-82%) compared to adults. Cyclophosphamide (CYC) and mycophenolate mofetil (MMF) are both treatment options…
  • Abstract Number: 1299 • ACR Convergence 2025

    Pediatric Antiphospholipid Syndrome in a Large Tertiary Center

    Rasha Elrefai, Marietta De Guzman, Jun Teruya, Vadim Kostousov, Amir Navaei and Olivia Kwan, Baylor College of Medicine, Houston, TX

    Background/Purpose: Antiphospholipid syndrome (APS) is an autoimmune condition defined as the presence of thrombotic events and/or pregnancy morbidity, accompanied by persistent antiphospholipid antibodies (aPLs). Pediatric…
  • Abstract Number: 1379 • ACR Convergence 2025

    Renal tubular acidosis in Sjögren’s disease and non-Sjögren’s sicca in an Oklahoma cohort

    Biji T Kurien1, Martha Tsaliki2 and R Hal Scofield1, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2OMRF, Oklahoma City, OK

    Background/Purpose: Renal involvement in primary Sjögren’s disease (pSjD) is a well-known extraglandular manifestation with a prevalence of 5-14% in several studies. Mostly, it affects the…
  • Abstract Number: 1344 • ACR Convergence 2025

    Exploring the Factors Associated with the Discontinuation of Tofacitinib in Patients with Rheumatoid Arthritis: A Retrospective Cohort Study

    yao fan fang1, Ping-Han Tsai2 and yen Fu CHEN3, 1Chang Gung memorial hopspital, Linkou, Taipei, New Taipei, Taiwan (Republic of China), 2Chang Gung memorial hospital, linkou, Taipei, Taiwan (Republic of China), 3Chang Gung memoriial hospital linkou, taipei, Taiwan (Republic of China)

    Background/Purpose: Tofacitinib is the first oral targeted synthetic disease-modify anti-rheumatic drug for patients with moderate to severe rheumatoid arthritis 1. This study aimed to identify…
  • Abstract Number: 1352 • ACR Convergence 2025

    Prediction of 5-Year Fracture Risk in Rheumatoid and Psoriatic Arthritis Using REMS Technology

    Marco Di Paola1, Edmund J MacLaughlin2, Kathleen Methric3, Maurizio Muratore4, Gianmarco Del Vecchio5, Giusy Peluso6, Ernesto Casciaro1, Fabiola Rosa Contaldo7, Fiorella Anna Lombardi1, Paola Pisani1, Francesco Conversano1 and Sergio Casciaro1, 1Institute of Clinical Physiology, National Research Council, Lecce, Puglia, Italy, 2Rheumatology Associates of Delmarva and BoneVue Diagnostics, Easton, MD, 3BoneVue Diagnostics, Catonsville, MD, 4ASL- LE, "Vito Fazzi" Hospital, Lecce, Puglia, Italy, 5Department of Research and Development, Echolight S.p.a., Lecce, Puglia, Italy, 6Department of Innovative Engineering, University of Salento, Lecce, Puglia, Italy, 7Department of Biological and Environmental Sciences and Technologies, University of Salento, University of Salento, Lecce, Puglia, Italy

    Background/Purpose: Autoimmune arthritis, including Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PA), are among the most common forms of inflammatory joint diseases. These conditions affect joints…
  • Abstract Number: 1355 • ACR Convergence 2025

    Use of parenteral compared to oral glucocorticoids in early rheumatoid arthritis is superior for chance ofbeing off steroids and escalation of therapy at 1 year

    Andreu Fernandez Codina1, Marie-France Valois2, Susan J. Bartlett3, Mishquatul Wahed4, Hugues Allard-Chamard5, Louis Bessette6, Glen Hazlewood7, Carol Hitchon8, Bindee Kuriya9, Vivian Bykerk10 and Janet Pope11, 1Western University, London, ON, Canada, 2McGill University, Pointe-Claire, QC, Canada, 3McGill University, Beaconsfield, QC, Canada, 4Western University, Windsor, ON, Canada, 5Université de Sherbrooke, Sherbrooke, Canada, 6Centre de l'Ostéoporose et de Rhumatologie de Québec, Quebec, QC, Canada, 7University of Calgary, Calgary, AB, Canada, 8University of Manitoba, Winnipeg, MB, Canada, 9University of Toronto - Toronto, Toronto, ON, Canada, 10Hospital for Special Surgery, New York, NY, 11University of Western Ontario, London, ON, Canada

    Background/Purpose: The 2023 EULAR recommendations for the management of Rheumatoid Arthritis (RA) emphasizes theimportance of limiting the dose and duration of glucocorticoids (GC) used in…
  • Abstract Number: 1275 • ACR Convergence 2025

    Fostering connections in Pediatric Rheumatology: A Narrative medicine intervention

    Anita Dhanrajani1, Joanne Drew2, Suzanne Edison3, Lakshmi Moorthy4, Ingrid Goh5, Alicia Garceau6, Hanna Saltzman7, Courtney Wells8 and Aviya Levy9, 1Manning Family Children's Hospital, Tulane University Medicine, New Orleans, LA, 2Nationwide Children's Hospital, Columbus, OH, 3Cure JM foundation, Seattle, WA, 4Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 5University of Toronto The Hospital for Sick Children, Toronto, ON, Canada, 6Self Employed, Indianapolis, 7University of Utah, Salt Lake City, UT, 8University of Wisconsin River falls, River Falls, WI, 9Rady Children's Hospital, San Diego, CA

    Background/Purpose: Patients with chronic diseases often report poor health-related quality of life (QOL) and impaired psychosocial functioning. The current model of healthcare in rheumatology emphasizes…
  • Abstract Number: 1317 • ACR Convergence 2025

    The Association Between Insomnia and Rheumatoid Arthritis: A Systematic Review and Meta-Analysis of 546,822 Patients

    Mohamed Abdelsalam1, Maryam Lasheen2, Menat Alla Ayman Ali Mahdy3, Hadeer Hafez4, Nourhan Abouelella5, Mohamed Al-Adl6 and Mohamed Reda Awad7, 1Misr University For Science and Technology, 6 october, Al Jizah, Egypt, 2Misr University For Science and Technology, Helwan, Al Qahirah, Egypt, 3Misr University For Science and Technology, Nasr City, Al Qahirah, Egypt, 46th October University, 6 october, Al Jizah, Egypt, 5Faculty of Medicine, Misr University for Science and Technology, 6 october, Al Jizah, Egypt, 6Faculty of medicine Al-Azhar University Cairo, Nasr City, Egypt, 7Al Azhar University, Cairo, Egypt, Giza, Al Jizah, Egypt

    Background/Purpose: Insomnia and rheumatoid arthritis (RA) are caught in a snowball effect, where chronic pain disrupts sleep and causes poor sleep quality, which in turn…
  • Abstract Number: 1281 • ACR Convergence 2025

    Ethnic Disparities in Mental Health Screening, Diagnoses, and Outcomes in Patients with Childhood-Onset Systemic Lupus Erythematosus

    Alicia Tran1, Indrani Das2, Zhaoyu Ding3, Daniela Dominguez4, Sefi Kronenberg5, Lawrence Ng6, Alene Toulany1, Gwyneth Zai7, Deborah Levy1, Andrea Knight8 and Linda Hiraki1, 1The Hospital for Sick Children, Toronto, ON, Canada, 2University of Toronto, Toronto, ON, Canada, 3SickKids Research Institute, Toronto, ON, Canada, 4The Hospital for Sick Children, Toronto, Canada, 5Holland Bloorview Kids Rehabilitation Hospital, Toronto, ON, Canada, 6The Hospital for Sick Children, Toronto, Canada, Toronto, ON, Canada, 7Centre for Addiction & Mental Health, Toronto, ON, Canada, 8Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Patients with childhood-onset systemic lupus erythematosus (cSLE) face higher risks of depression and anxiety compared to healthy peers. In 2022, standardized mental health (MH)…
  • Abstract Number: 1362 • ACR Convergence 2025

    Multimodal Spatial and Single-Cell Profiling of Synovial Tissue Reveals Macrophage Programs Associated with Biologic TherapyTreatment Response in Rheumatoid Arthritis

    Mohammad Daud Khan1, Matthew Dapas2, Salina T Dominguez1, Tyler Therron3, Kathleen Aren4, Mary Carns5, Hadijat Makinde5, Arthur M Mandelin1, Eric M Ruderman1, John F Seagrist5, Ruth Misha1, Carla Marie Cuda5, Harris R Perlman5 and Deborah Rachelle Winter6, 1Northwestern University, Chicago, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3Northwestern Feinberg School of Medicine, Chicago, IL, 4Northwestern University Division of Rheumatology, Chicago, IL, 5Northwestern University, Chicago, IL, 6Northwestern University, Skokie, IL

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disease driven by persistent synovial inflammation and progressive joint damage. Selecting an effective biologic therapy remains a…
  • Abstract Number: 1358 • ACR Convergence 2025

    Real-World Evidence for the Superiority of Subcutaneous Methotrexate in RA: A Comparative Observational Study with Ultrasonographic Assessment

    Masatsugu Komagamine1, Sari Taguchi2, Masataka Komagamine2, Tetsuji Naka1 and Minoru Fujimoto1, 1Division of Allergy and Rheumatology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan, 2Komagamine Rheumatology and Orthopedic Clinic, Morioka, Japan

    Background/Purpose: Methotrexate (MTX) is a foundational agent in the management of rheumatoid arthritis (RA). While oral MTX is widely prescribed, its subcutaneous (SC) formulation may…
  • Abstract Number: 1361 • ACR Convergence 2025

    Efficacy of Telitacicept in the treatment of Connective tissue disease-associated interstitial lung disease: A Potential therapeutic option

    Mingfang Sun1, Xue Chen2, Ying Zhou2, Yanlong Yang2, Fei Xiao2 and huanzi dai2, 1Daping Hospital, chongqing, China (People's Republic), 2Daping Hospital & Research Institute of Surgery, Army Medical University, Chongqing, PR China., Chongqing, China (People's Republic)

    Background/Purpose: Connective tissue disease-associated interstitial lung disease(CTD-ILD) represents a significant cause of mortality among patients. Presently, research on treatment options for CTD-ILD is limited, with…
  • Abstract Number: 1286 • ACR Convergence 2025

    Response to Hydroxychloroquine in Immune Thrombocytopenia in Childhood-Onset Systemic Lupus Erythematosus

    Hamada Natour1, Y. Ingrid Goh1, Daniela Dominguez2, Nicholas Gold1, Lawrence Ng3, Andrea Knight4, Earl Silverman1, Brian Feldman1, Linda Hiraki1 and Deborah Levy1, 1The Hospital for Sick Children, Toronto, ON, Canada, 2The Hospital for Sick Children, Toronto, Canada, 3The Hospital for Sick Children, Toronto, Canada, Toronto, ON, Canada, 4Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: The management of immune thrombocytopenia in childhood-onset systemic lupus erythematosus (cSLE) is not standardized. We examined the efficacy and safety of hydroxychloroquine (HCQ) as…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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