Abstracts Archive - Page 110 of 2607 - ACR Meeting Abstracts

Abstract Number: 1213 • ACR Convergence 2025
Transitional Changes on High Resolution Computed Tomography (HRCT) in idiopathic inflammatory Myopathy- Associated Interstitial Lung Disease (IIM-ILD)
Sangmee Bae¹, Grace Kim², Jihey Lee², Daniela Markovic², Donald Tashkin², Jonathan Goldin², Rohit Aggarwal³ and Christina Charles-Schoeman⁴, ¹UCLA Rheumatology, Los Angeles, CA, ²UCLA, Los Angeles, ³University of Pittsburgh, Rheumatology and Clinical Immunology, Pittsburgh, United States of America, Pittsburgh, PA, ⁴UCLA Medical Center, Santa Monica, CA
Background/Purpose: HRCT is used as a surrogate for important histopathological findings when evaluating patients with interstitial lung disease (ILD). Quantitative imaging analysis (QIA) using CT…
Abstract Number: 1234 • ACR Convergence 2025
Serum Antibodies Against Glial Fibrillary Acidic Protein in Fibromyalgia: A Proof-of-Concept Study
Felipe Massó¹, Laura Aline Martinez-Martinez², Luis M Amezcua-Guerra³, Francisco Mercado⁴, Angélica Almanza⁵ and Manuel Martínez-Lavín¹, ¹Instituto Nacional de Cardiologia Ignacio Chavez, Mexico city, Mexico, ²Rheumatology Department at National Institute of Cardiology Ignacio Chávez, Mexico City, Federal District, Mexico, ³Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico, Mexico city, ⁴Instituto Nacional de Psiquiatría Ramón del la Fuente Muñiz, Mexico city, Mexico, ⁵Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Mexico city, Mexico
Background/Purpose: Fibromyalgia (FM) is a stress-related disorder in which dorsal root ganglia (DRG) may play a pivotal pathogenetic role. DRG exhibit unique stress-induced, pro-algesic physio-anatomy,…
Abstract Number: 1291 • ACR Convergence 2025
Gastrointestinal Tract Involvement in Juvenile Systemic Sclerosis: Results from an International Scoping Review of Outcome Measures
Lauren Robinson¹, Lusine Ambartsumyan², Emily Willis³, Aybuke Gunalp⁴, Simone Appenzeller⁵, Ozgur Kasapcopur⁶, Sarah Ishaq⁷, Natalia Vasquez Canizares⁸ and Suzanne Li⁹, ¹Hospital for Special Surgery, New York, NY, ²Seattle Children's Hospital, Seattle, WA, ³Royal Manchester Children's Hospital, Manchester, United Kingdom, ⁴Cerrahpasa Medicine School, Cerrahpasa, Istanbul, Turkey, ⁵Unicamp, Campinas, São Paulo, Brazil, ⁶Istanbul University-Cerrahpasa, Cerrahpasa Medical School, istanbul, Turkey, ⁷Osteopathic Medicine , Touro College of Osteopathic Medicine, New York, NY, ⁸Children's Hospital at Montefiore, New York, NY, ⁹Joseph M. Sanzari Children's Hospital and Hackensack Meridian School of Medicine, Hackensack, NJ

Background/Purpose: Gastrointestinal (GI) tract involvement is nearly universal in patients with systemic sclerosis (SSc) leading to significant morbidity and mortality. In a North American juvenile…
Abstract Number: 1268 • ACR Convergence 2025
Development of the LupusCoach Chatbot: Results of a Focus Group
Leila Khalili¹, Pooja Desai², Maya Souvignier², Adrienne Pichon², Stephen Suh³, Alberto Nordmann-Gomes², Lena Mamykina² and Anca Askanase¹, ¹Columbia University Medical Center, New York, NY, ²Columbia University Irving Medical Center, New York, NY, ³Columbia University Irving Medical Center, New York City, NY
Background/Purpose: Self-management education and coaching are successful interventions for managing chronic health conditions. However, accessibility of in-person coaching is limited; digital coaching is available and…
Abstract Number: 1017 • ACR Convergence 2025
Effectiveness of Recombinant Zoster Vaccine in Reducing Herpes Zoster Incidence and All-Cause Mortality Among Rheumatoid Arthritis Patients: A Retrospective Cohort Study of 21,046 Individuals from TriNetX U.S. Collaborative Network
James Wei¹, Shiow-Ing Wang² and Ying-Li Lin², ¹Chung Shan Medical University Hospital, Taichung, Taichung, Taiwan (Republic of China), ²Chung Shan Medical University Hospital; China Medical University, Taichung, Taiwan (Republic of China)
Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk of developing herpes zoster (HZ). This study aimed to assess the effectiveness of recombinant zoster…
Abstract Number: 1189 • ACR Convergence 2025
Clinical Outcomes and Response to SARS-Cov-2 Infection and Vaccination in Ianalumab‑Treated Patients with Autoimmune Diseases
Valerie Devauchelle¹, Swati Ghanshani², CAROLE SIPS³, Rainer Hillenbrand³, Carol Lau⁴, Wolfgang Hueber⁵, Claire Bonal³ and Stephen Oliver⁶, ¹UBO, Brest, France, ²Novartis Healthcare Private Limited, Hyderabad, India, Hyderabad, India, ³Novartis Pharma AG, Basel, Switzerland, Basel, Switzerland, ⁴Novartis Pharmaceuticals Corporation, East Hanover, ⁵Novartis Pharmaceuticals, Basel, Switzerland, ⁶Novartis Pharma AG, Basel, Switzerland
Background/Purpose: Ianalumab, a glycoengineered IgG1 mAb directed against B cell-activating factor (BAFF)-receptor (BAFF-R), targets B cells and their functions via dual mechanism: depletion of B…
Abstract Number: 1171 • ACR Convergence 2025
VEXAS Syndrome Under the Lens: A prospective analysis of temporal disease patterns, biomarker Dynamics, and therapeutic efficacy
Marta López¹, Paula Garcia Escudero², Berta Magallares³, Meritxell Salles Lizarzaburu⁴, Dolly Viviana Fiallo Suárez⁵, Iñigo Rúa-Figueroa⁶, Isla Morante Bolado⁷, Elena Aurrecoechea⁸, Eugenia Enriquez⁹, Carolina Merino¹⁰, Santos Castañeda¹¹, Irene Monjo Henry¹², César Antonio Egües Dubuc¹³, Elena María Oliver García¹⁴, Alicia Garcia¹⁵, Judit Font-Urgelles¹⁶, Cristina Corrales¹⁷, Lourdes Villalobos¹⁸, Alina-Lucica Boteanu¹⁹, Ignacio Vázquez Gómez²⁰, Diego Dios²¹, Clara Garcia Belando²², Beatriz Frade Sosa²³, Delia Reina²⁴, Marta Ibañez²⁵, Irene Carrion²⁶, Maria Rodriguez²⁷, cristiana Sieiro²⁸, Francisco Javier Toyos²⁹, Alberto Mariano³⁰, Clara Moriano³¹, Rafael B. Melero-González³², Paloma Vela Casasempere³³, Jose Alberto Miranda³⁴, Giuliano Boselli³⁵, Jose Angel Hernandez³⁶, Ernesto Trallero³⁷, Elena Riera Alonso³⁸ and Jaime Calvo³⁹, ¹Complex Hospitalari Universitari Moisés Broggi, Barcelona, Spain, ²H.U.Araba, Vitoria, ³Hospital de Sant Pau, Bareclona, ⁴Rheumatology Department, Althaia Xarxa Assistencial Universitària Manresa Manresa (Spain)., Manresa, Spain, ⁵H.U. Doctor Negrín, Gran Canarias, ⁶Hospital de Gran Canaria Doctor Negrin, Las Palmas GC, Spain, ⁷Rheumatology, Hospital General Sierrallana, Torrelavega, Spain., Santander, ⁸H. Sierrallana, Santander, ⁹Clínica Universidad de Navarra, Madrid, Spain, ¹⁰Rheumatology department. Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda (Madrid), Madrid, Spain, ¹¹Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Madrid, Spain, ¹²Hospital Universitario La Paz, Madrid, Spain, ¹³Rheumatology Department, Donostia University Hospital., San Sebastian, Spain, ¹⁴H.C. U. Lozano Blesa, Zaragoza, ¹⁵Rheumatologist, La Laguna, Spain, ¹⁶Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ¹⁷HOSPITAL UNIVERSITARIO MARQUES DE VALDECILLA, Santander, Spain, ¹⁸Ramon y Cajal Hospital, MADRID, Spain, ¹⁹H.U. Ramón y Cajal, Madrid, Spain, ²⁰H.U. Doctor Peset, Valencia, ²¹H.U de A Coruña, A Coruña, Spain, ²²H.C. U. Virgen de la arrizaca, Murcia, ²³Hospital Clinic de Barcelona, Barcelona, Catalonia, Spain, ²⁴Complex Hospitalari Moisès Broggi, Barcelona, Spain, ²⁵Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, Catalonia, Spain, ²⁶Hospital del Mar, Barcelona, Spain, ²⁷H. Clínico San Carlos, Madrid, Spain, ²⁸Univrsity of Manchester, Manchester, United Kingdom, ²⁹Virgen Macarena University Hospital,, Sevilla, Spain, ³⁰Virgen del Rocío University Hospital, Sevilla, Spain, ³¹Hospital León, LEON, Castilla y Leon, Spain, ³²COMPLEXO HOSPITALARIO UNIVERSITARIO DE OURENSE, O Carballino, Spain, ³³Hospital General Universitario Alicante, Alicante, Comunidad Valenciana, Spain, ³⁴C. H. U. Lucus Augusti, Lugo, Spain, ³⁵Rheumatology Division, Hospital Universitario Miguel Servet , Zaragoza, Spain, Zaragoza, Aragon, Spain, ³⁶Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran CanariaHospital, Spain, ³⁷H. U. Vall d'Hebron, Barcelona, ³⁸Hospital Universitari Mùtua Terrassa, Terrassa, Spain, ³⁹Department of Rheumatology, Hospital Universitario Araba, School of Medicne, Universidad del País Vasco, BIOARABA Health Research Institute, Vitoria, Spain, Vitoria, Pais Vasco, Spain
Background/Purpose: VEXAS syndrome is an adult-onset autoinflammatory disorder caused by somatic mutations in UBA1 gene, characterized by systemic inflammation and haematologic abnormalities. Evidence regarding its…
Abstract Number: 1184 • ACR Convergence 2025
Does Blocking IL-17 Treat Recalcitrant Uveitis? Explorative Study on the Use of Ixekizumab to Manage Patients with Uveitis.
Sergio Schwartzman¹, Stephen Anesi², Yasmin Massoudi², Monica Schwartzman³ and Peter Chang², ¹Weill Cornell Medical Center, New York Presbyterian Hospital, and Hospital for Special Surgery, New York, NY, ²MERSI, Waltham, ³Hospital for Special Surgery/New York Presbyterian Hospital-Weill Cornell Medical Center, New Rochelle, NY
Background/Purpose: Non-infectious uveitis can exist as a primary autoimmune disease or can be a manifestation of an underlying systemic illness. Despite the availability of new…
Abstract Number: 1309 • ACR Convergence 2025
Transcriptomic biomarkers of progression from undifferentiated arthritis to rheumatoid arthritis
Christina Printzis¹, Keerthana Nagesh Prabhu², Regina Sakalyte³, Sigita Stropuviene³ and Damini Jawaheer¹, ¹Northwestern University, Chicago, IL, ²Washington University in St. Louis, St Louis, MO, ³Vilnius University, Faculty of Medicine, Institute of Clinical Medicine, Clinic of Rheumatology, Orthopedics Traumatology and Reconstructive Surgery, Vilnius, Lithuania
Background/Purpose: A broad range (6-55%) of patients classified as having undifferentiated arthritis (UA) tend to progress to rheumatoid arthritis (RA), suggesting that UA in these…
Abstract Number: 1278 • ACR Convergence 2025
Differences in Patient and Provider Perception of Functional Status in Adolescents with Lupus
Emily Masi¹, Kimberly Rapoza², Tamar Rubinstein³, Kathy Kenney-Riley⁴ and Joyce Hui-Yuen⁵, ¹Cohen Children's Medical Center, North New Hyde Park, NY, ²Mercy College, Dobbs Ferry, NY, ³Albert Einstein College of Medicine, White Plains, NY, ⁴Mercy University, Dobbs Ferry, NY, ⁵North Shore LIJ Health System, Great Neck, NY
Background/Purpose: Patient and provider discordance can negatively impact medication adherence and disease outcomes in pediatric lupus. Functional status is known to greatly affect perception of…
Abstract Number: 1024 • ACR Convergence 2025
Mortality In Progressive Pulmonary Fibrosis Associated to Autoimmune Diseases: NEREA Registry
Marta Ruiz-Valdepeñas Almansa¹, CLARA DE MIGUEL², DALIFER FREITES³, Cristina Vadillo Font⁴, Maria asuncion Nieto⁴, Olga Sanchez Pernaute⁵, fredeswinda Romero-Bueno⁶, Mª Jesus Rodriguez-Nieto⁷, Rosalia Laporta⁸, Hilda Godoy Tundidor⁹, Jesús Loarce¹⁰, Juan A Rigual¹¹ and lydia Abasolo Alcazar¹², ¹HOSPITAL CLINICO SAN CARLOS, Madrid, Spain, ²HOSPITAL CLINICO SAN CARLOS, Madrid, Madrid, Spain, ³Rheumatology Service, San Carlos Clinical Hospital, Madrid, Madrid, Spain, ⁴Hospital Clínico S Carlos, Madrid, Spain, ⁵Clinica Universidad de Navarra, Madrid, Madrid, Spain, ⁶University Hospital Fundación Jiménez Díaz"", Madrid, Spain, ⁷Fundacion Jimenez Diaz (IIS-HUFJD), Madrid, Spain, ⁸Hospital Puerta de Hierro Majadahonda, Madrid, Spain, ⁹Hospital Universitario puerta de hierro, Madrid, Spain, ¹⁰HOSPITAL RAMÓN Y CAJAL, MADRID, Madrid, Spain, ¹¹Hospital Ramón y Cajal, Madrid, Spain, ¹²IdISSC. HCSC, Madrid, Madrid, Spain
Background/Purpose: Autoimmune interstitial lung disease (ILD) may arise in various autoimmune rheumatic diseases (ARD). Some patients develop ILD with systemic symptoms and autoantibodies without fulfilling…
Abstract Number: 1283 • ACR Convergence 2025
Impact of Guideline Concordant Care of Renal Outcomes in Childhood-Onset Lupus Nephritis
Alisha Akinsete¹, Orysya Soroka², Mangala Rajan², Karen Onel³, Monika Safford² and Iris Navarro-Millan⁴, ¹Weill Cornell Medical Center, New York, NY, ²Weill Cornell Medicine, New York, ³HSS, New York, NY, ⁴Weill Cornell Medicine, Hospital for Special Surgery, Poughkeepsie, NY
Background/Purpose: End-stage renal disease (ESRD) is a serious complication of lupus nephritis (LN), yet the effect of guideline-concordant care on this outcome is unclear. Despite…
Abstract Number: 1194 • ACR Convergence 2025
Risk of Calcinosis with Proton Pump Inhibitor Use in Adult Dermatomyositis and Systemic Sclerosis
Antonia Valenzuela¹, Nicolás González², José Rojas³, Martin Fuentes³, Srijana Davuluri⁴, Brian Lee⁵, David Fiorentino⁶ and Lorinda Chung⁴, ¹Pontificia Universidad Catolica de Chile, Santiago, Chile, ²Pontificia Universidad Católica de Chile, Santiago de Chile, Chile, ³Pontificia Universidad Católica de Chile, Santiago de Chile, Chile, ⁴Stanford University, Stanford, CA, ⁵Stanford University, Stanford, ⁶Department of Dermatology, Stanford University Medical Center, Stanford, CA
Background/Purpose: Calcinosis is a painful, debilitating manifestation in connective tissue diseases. Recent findings suggest a link between proton pump inhibitor (PPI) use and calcinosis in…
Abstract Number: 1127 • ACR Convergence 2025
The Pathogenetic Role of Calcium Pyrophosphate and Basic Calcium Phosphate Crystals in Osteoarthritis: Associations with Synovial Fluid Cytokines and Clinical Indices
Francesca Oliviero¹, Chiara Baggio², Amelia Damasco², Federico Zorzi³, Mariagrazia Lorenzin², Giacomo Cozzi² and Roberta Ramonda⁴, ¹Rheumatology Unit, Department od Medicine - DIMED, University of Padova, Padova, Veneto, Italy, ²Rheumatology Unit, Department of Medicine - DIMED, University of Padova, Padova, Veneto, Italy, ³Center for Analysis and Certification Services (CEASC), University of Padova, Padova, Veneto, Italy, ⁴Rheumatology Unit-DIMED-University of Padova ITALY, Padova, Padua, Italy
Background/Purpose: Calcium pyrophosphate (CPP) and basic calcium phosphate (BCP) crystals are frequent features of synovial fluid (SF) in patients with osteoarthritis (OA). Although these crystals…
Abstract Number: 1287 • ACR Convergence 2025
A clear pattern of clinical presentation in juvenile systemic scleroderma is associated with interstitial lung disease
Ivan Foeldvari¹, Kathryn Torok², Ozgur Kasapcopur³, Amra Adrovic⁴, Flavio Sztajnbok⁵, Maria Teresa Terreri⁶, Ana Sakamoto⁷, Jordi Anton⁸, Raju Khubchandani⁹, Sindhu Johnson¹⁰, Gülcan Özomay Baykal¹¹, Brian Feldman¹², Dieneke Schonenberg-Meinema¹³, Sujata Sawhney¹⁴, Vanessa Smith¹⁵, Eslam Al-Abadi¹⁶, Simone Appenzeller¹⁷, Stefanie Hajek¹⁸, Maria Katsicas¹⁹, Mikhail Kostik²⁰, Suzanne Li²¹, Hana Malcova²², Anjali Patwardhan²³, Walter Alberto Sifuentes-Giraldo²⁴, Natalia Vasquez-Canizares²⁵, Tadej Avcin²⁶, Patricia Costa Reis²⁷, Siri Opsahl Hetlevik²⁸, Mahesh Janarthanan²⁹, Edoardo Marrani³⁰, Clare Pain³¹, Maria Jose Santos³², Valda Stanevica³³, Sima Abu Alsaoud³⁴, Ekaterina Alexeeva³⁵, Cristina Battagliotti³⁶, Lillemor Berntson³⁷, blanca e r bica³⁸, Jürgen Brunner³⁹, Despina Eleftheriou⁴⁰, Liora Harel⁴¹, Tilmann Kallinich⁴², Dragana Lazarevic⁴³, Kirsten Minden⁴⁴, Dana Nemcova⁴⁵, Susan Nielsen⁴⁶, Farzana Nuruzzaman⁴⁷, Mihaela Sparchez⁴⁸, Yosef Uziel⁴⁹ and Nicola Helmus⁵⁰, ¹Hamburger Zentrum für Kinder- und Jugendrheumatologie, Hamburg, Germany, ²University of Pittsburgh, Pittsburgh, PA, ³Istanbul University-Cerrahpasa, Cerrahpasa Medical School, istanbul, Turkey, ⁴Istanbul University-Cerrahpasa, Cerrahpasa Medical School, Turkey, Turkey, ⁵UFRJ/UERJ, SAO PAULO, Brazil, ⁶UNIFESP, São Paulo, São Paulo, Brazil, ⁷Federal University of São Paulo (UNIFESP), São Paulo, São Paulo, Brazil, ⁸Hospital Sant Joan de Düu. Universitat de Barcelona, Esplugues de Llobregat (Barcelona), Spain, ⁹Jaslok Hospital and Research Center, Mumbai, India, ¹⁰Division of Rheumatology, Department of Medicine, Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western and Mount Sinai Hospitals; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada, ¹¹Umraniye Training and Research Hospital, Istanbul, Turkey, ¹²The Hospital for Sick Children, Toronto, ON, Canada, ¹³Emma Children’s Hospital, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands, ¹⁴Sir Ganga Ram Hospital, Sector ³⁷ noida, Uttar Pradesh, India, ¹⁵Ghent University Hospital, Gent, Belgium, ¹⁶Birmingham Women’s and Children’s Hospital NHSFT, Birmingham, United Kingdom, ¹⁷Unicamp, Campinas, São Paulo, Brazil, ¹⁸Deutsches Zentrum für Kinder- und Jugendrheumatologie, Garmisch-Partenkirchen, Germany, ¹⁹Hospital Garrahan, Buenos Aires, Argentina, ²⁰Saint-Petersburg State Pediatric Medical University, Saint Petersburg, Russia, ²¹Joseph M. Sanzari Children's Hospital and Hackensack Meridian School of Medicine, Hackensack, NJ, ²²Motol University Hospital, Prague, Czech Republic, ²³University of Missouri-Columbia, Columbia, MO, ²⁴Hospital Universitario Ramón y Cajal, Madrid, Spain, ²⁵Children’s Hospital at Montefiore, Bronx, NY, ²⁶University Children's Hospital University Medical Center Ljubljana, Ljubljana, Slovenia, ²⁷Hospital de Santa Maria, Lisbon, Portugal, ²⁸Oslo University Hospital, Oslo, Norway, ²⁹SRI RAMACHANDRA INSTITUTE OF HIGHER EDUCATION AND RESEARCH, Chennai, Tamil Nadu, India, ³⁰Meyer Children Hospital IRCCS, Firenze, Italy, ³¹Alder Hey NHS Trust, Liverpool, United Kingdom, ³²Hospital Garcia de Orta, Almada, Lisboa, Portugal, ³³Childrens Clinical University Hospital, Zemgales priekšpilseta, Riga, Latvia, ³⁴Caritas baby Hospital, Jerusalem, Palestine, ³⁵National Medical Research Center for Children’s Health Federal State Autonomous Institution of the Russian Federation Ministry of Health and I.M. Sechenov First Moscow State Medical University (Sechenovskiy University), Moscow, Russia, ³⁶Hospital de Niños Dr Orlando Alassia, Santa Fe, Argentina, ³⁷Dept. of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden, ³⁸UNIVERSIDADE FEDERAL DO RIO DE JANEIRO, Rio de Janeiro, Brazil, ³⁹Medical University Innsbruck; Department of Pediatrics, Pediatric Rheumatology, Innsbruck, Austria, ⁴⁰Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom, ⁴¹Schneider Children's Medical center, Nettnja, Israel, ⁴²Charite University Medicine Berlin, Berlin, Germany, ⁴³Dept of Pediatric Rheumatology and Immunology Clinical Center Nis, Faculty of Medicine, University of Niš, Nis, Serbia, ⁴⁴German Rheumatism Research Center, Berlin, Germany, ⁴⁵Charles University, Prague, Czech Republic, ⁴⁶Rigshospitalet, Copenhagen, Denmark, ⁴⁷Stony Brook Children's Hospital, Stony Brook, NY, ⁴⁸Emergency Clinical Hospital for Children, Cluj-Napoca, Romania, ⁴⁹Pediatric Rheumatology Unit, Meir Medical Center, Kfar Saba, Sackler School of Medicine, Tel Aviv University, Kfar Saba, Israel, ⁵⁰Hamburg Centre for Pediatric and Adolescence Rheumatology, Hamburg, Germany
Background/Purpose: Juvenile systemic sclerosis(jSSc) is an orphan disease with a prevalence of 3 in 1 000 000 children. In adult systemic sclerosis is interstitial lung…

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