ACR Meeting Abstracts

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  • Abstract Number: 1386 • 2018 ACR/ARHP Annual Meeting

    Golimumab Improves Work Productivity and Activity As Well As Quality of Life in Patients with Rheumatoid Arthritis (RA), Psoriasis Arthritis (PsA) and Axial Spondyloarthritis (axSpA): Interim Results from a Non-Interventional Study in Austria (Go Active)

    Christian Dejaco1, Thomas Mueller2, Omid Zamani, MD3, Ulrike Kurtz, MD4, Stefan Egger, MD5, Johannes Resch Passini, MD6, Anna Totzauer, MD7, Wolfgang Eisterer8, Babak Yazdani-Biuki, MD, Univ.Doc.9, Thomas Schwingenschloegl, MD10, Peter Peichl, MD. Univ.Doc. Msc11, Angelika Kraus12, Gerhard Naerr, PhD13 and Verena Rickert, MD. MBA14, 1Rheumatology and Immunology, Medical University Graz, Graz, Austria, 2Private Office Dr. Thomas Mueller, Graz, Austria, 3Rheuma Zentrum Favoriten, Vienna, Austria, 4Rheuma Praxis Dr. Kurtz, Gleisdorf, Austria, 5Ordination Gesundheitsquadrat, Vienna, Austria, 6Rheumatology Department, Rheuma-Zentrum Wien-Oberlaa GmbH, Vienna, Austria, 7Private Office Dr. Anna Totzauer, Gmuend, Austria, 8Department of Hematology and Internal Oncology, KLINIKUM- KLAGENFURT am WÖRTHERSEE, Klagenfurt, Austria, 9Dr. Schrenk & Dr. Yazdani-Biuki OG - Gruppenpraxis, Fuerstenfeld, Austria, 10Private Office Dr. Thomas Schwingenschloegl, Wiener Neudorf, Austria, 11Private Office Prim. Univ. Doz. Dr. Peter Peichl, MSc, Vienna, Austria, 12Private Office, Private Office Angelika Kraus, Melk, Austria, 13Medical Affairs, Merck Sharp & Dohme GmbH, Vienna, Austria, 14Medical Affairs, Merck Sharp&Dohme GmbH, Vienna, Austria

    Background/Purpose: Golimumab has shown clinical efficacy and tolerability within its clinical trial program. No systematic outcome data regarding patient‐reported outcomes and health economic parameters reflecting…
  • Abstract Number: 1387 • 2018 ACR/ARHP Annual Meeting

    Fatigue in Patients with Rheumatoid Arthritis As Compared to Different Groups of Cancer Patients

    Jens Gert Kuipers1, Michael Koller2, Ulrich Rueffer3, Florian Zeman2, Karolina Mueller4 and Joachim Weis5, 1Clinic for Internal Rheumatology, Red Cross Hospital Bremen, Bremen, Germany, 2Center of Clinical Studies, University Hospital Regensburg, Regensburg, Germany, 3German Fatigue Society, Cologne, Germany, 4Center for Clinical Studies, University Hospital Regensburg, Regensburg, Germany, 5University Clinic Centre Freiburg, Freiburg, Germany

    Background/Purpose: Fatigue is a common symptom in patients with rheumatoid arthritis (RA) as well as patients with cancer. Fatigue considerably reduces the quality of life…
  • Abstract Number: 1388 • 2018 ACR/ARHP Annual Meeting

    Characteristics and Symptom Severity in 21,101 Patients Reporting Systemic Lupus Erythematous in the Patientslikeme Online Health Community

    Elisabeth Nyman1, Edward R. Hammond2, Timothy Vaughan3, Barnabas Desta2, Xia Wang2, Volkan Barut4 and Cathy Emmas5, 1Advanced Analytics Centre, AstraZeneca, Gothenburg, Sweden, 2AstraZeneca, Gaithersburg, MD, 3PatientsLikeMe, Boston, MA, 4Global Medical Affairs, AstraZeneca, Cambridge, United Kingdom, 5Patient Centricity, AstraZeneca, Cambridge, United Kingdom

    Background/Purpose: Online health communities and research networks such as PatientsLikeMe (PLM) provide important insight into understanding chronic diseases, including systemic lupus erythematous (SLE). We aimed…
  • Abstract Number: 1389 • 2018 ACR/ARHP Annual Meeting

    Depression and the Patient Reported Outcomes Measurement Information System in Systemic Lupus Erythematosus

    Brett Dietz1, Patricia Katz1, Maria Dall'Era2, Louise Murphy3, Cristina Lanata1, Laura Trupin1 and Jinoos Yazdany2, 1University of California San Francisco, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA, 3Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA

    Background/Purpose: Health-related quality of life (HRQoL) is reduced in SLE. Depression is a possible contributor to reduced HRQoL. The relationship between major depression and HRQoL…
  • Abstract Number: 1390 • 2018 ACR/ARHP Annual Meeting

    Impact of Psoriatic Arthritis from the Patient’s Perspective in the Context of the Psoriatic Arthritis Impact of Disease (PsAID) Questionnaire: An Online Global Survey

    Laura C. Coates1, Ana-Maria Orbai2, Valderilio F Azevedo3, Joseph C Cappelleri4, Jade Moser5, Ralph Lippe6, Irwin Lim7, Lihi Eder8, Pascal Richette9, Meng-Yu Weng10, Rubén Queiro11 and Lara Fallon12, 1University of Oxford, Oxford, United Kingdom, 2Johns Hopkins University School of Medicine, Baltimore, MD, 3Universidade Federal do Paraná, Curitiba, Brazil, 4Pfizer Inc, Groton, CT, 5The Harris Poll, Rochester, NY, 6Pfizer Pharma GmbH, Berlin, Germany, 7BJC Health, Sydney, Australia, 8Women’s College Research Institute, University of Toronto, Toronto, ON, Canada, 9Lariboisière Hospital, Lariboisière, University of Paris 7, Paris, France, 10Department of Internal Medicine, Division of Allergy, Immunology and Rheumatology, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan, 11Rheumatology Division, HUCA, Oviedo, Spain, 12Pfizer Canada, Montreal, QC, Canada

    Background/Purpose: Psoriatic arthritis (PsA) is a complex disease with high impact on quality of life (QoL). The PsA core domain set1 includes pain, patient (pt)…
  • Abstract Number: 1391 • 2018 ACR/ARHP Annual Meeting

    Patient-Acceptable Symptom State in Psoriatic Arthritis: Prevalence and Associated Factors in Real Clinical Practice

    Rubén Queiro1, Juan Cañete2, Carlos Alberto Montilla-Morales3 and Miguel A. Abad4, 1Rheumatology Division, HUCA, Oviedo, Spain, 2Rheumatology Service, Hospital Clínic de Barcelona, Barcelona, Spain, 3Hospital Clínico Universitario de Salamanca. Spain, Salamanca, Spain, 4FEA Reumatología, Hospital Virgen del Puerto, Cáceres, Spain

    Background/Purpose: Treatment goals in psoriatic arthritis (PsA) are remission or low disease activity. We know little about whether these objectives correlate well with a patient-acceptable…
  • Abstract Number: 1392 • 2018 ACR/ARHP Annual Meeting

    Decreased Injection Site Pain Associated with New Etanercept Formulation in Patients with Rheumatoid Arthritis or Psoriatic Arthritis

    Stanley Cohen1, Ahmed Samad2, Elaine Karis2, Bradley S. Stolshek2, Mona Trivedi2, Hao Zhang2, Girish A. Aras2, Greg Kricorian2 and James Chung2, 1Metroplex Clinical Research Center, Dallas, TX, 2Amgen Inc., Thousand Oaks, CA

    Background/Purpose: Injection site pain (ISP) is a component of the patient experience with injectable drugs. A new formulation of etanercept was developed to reduce ISP.…
  • Abstract Number: 1393 • 2018 ACR/ARHP Annual Meeting

    Fatigue in Men and Women with Psoriatic Arthritis: An International Qualitative Study

    Ana-Maria Orbai1, Suzanne Grieb2, Lilian van Tuyl3, Penelope Palominos4, Ying Ying Leung5, Karen Schipper6, Willemina Campbell7, Jessica Walsh8, Katherine Clegg Smith9, Laure Gossec10, Tania Gudu11, Premarani Sinnathurai12, Lyn March13, Soumya M. Reddy14, Xin Xiao Hui15, Clifton O. Bingham III16, Ricardo M. Xavier17 and Maarten de Wit18, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins Bayview Medical Center, Center for Child and Community Health Research, Baltimore, MD, 3Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands, 4Rheumatology, Hospital de Clinicas de Porto Alegre, Santa Cecilia, Brazil, 5North District Hospital, Hong Kong, China, 6VU University, Amsterdam, Netherlands, 7Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, 8University of Utah School of Medicine, Salt Lake City, UT, USA, Salt Lake City, UT, 9Health, Behavior and Society, Johns Hopkins University Bloomberg School of Public Health, Batimore, MD, 10Sorbonne Universités, Paris, France, 11University of Medicine Carol Davila Bucuresti, Romania, Bucuresti, Romania, 12Rheumatology, University of Sydney, Sydney, Australia, 13Department of Rheumatology, Northern Clinical School, Institute of Bone and Joint Research, Kolling Institute, University of Sydney & Department of Rheumatology, Royal North Shore Hospital, St Leonards, Sydney, Australia, 14Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 15Rheumatology, Singapore General Hospital, Singapore, Singapore, 16Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 17Universidade Federal do Rio Grande do Sul Porto Alegre, Rio Grande do Sul, Brazil, 18EULAR standing committee of PARE, Zurich, Switzerland

    Background/Purpose: Fatigue is prevalent and important to people with psoriatic arthritis (PsA)1.  Women with PsA have worse symptom and life impact scores than men, including…
  • Abstract Number: 1394 • 2018 ACR/ARHP Annual Meeting

    Development and Pilot of a Patient Satisfaction Scale in Rheumatology

    Antonia Valenzuela1, Khushboo Sheth2, Stanford Shoor2, Philip L. Ritter2 and Kate Lorig3, 1Immunology and Rheumatology, Stanford University, Palo Alto, CA, 2Immunology & Rheumatology, Stanford University, Palo Alto, CA, 3Stanford University, Palo Alto, CA

    Background/Purpose: Patient satisfaction has been studied as a performance improvement measure in clinical practice among patients with a variety of diseases, but to date there…
  • Abstract Number: 1395 • 2018 ACR/ARHP Annual Meeting

    Could the Shortening of the Electronic Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) Questionnaire Improve Its Metric Properties?

    Maud Wieczorek1, Christine Rotonda1, Jonathan Epstein1,2, Francis Guillemin1,2 and Anne-Christine Rat1,3, 1Université de Lorraine, EA4360, APEMAC, Nancy, France, 2Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, 3Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France

    Background/Purpose: The aim of this study was to assess the validity of a short version of the electronic OAKHQOL questionnaire in a combined analysis with…
  • Abstract Number: 1396 • 2018 ACR/ARHP Annual Meeting

    Factors Associated with Specific Quality of Life Evolution in SLE Patients: A French Prospective Longitudinal Multicenter Study

    Hervé Devilliers1, Marie Corneloup2, Francois Maurier3, Denis Wahl4,5, Geraldine Muller6, Olivier Aumaître7, Pascal Sève8, Gilles Blaison9, Jean-Loup Pennaforte10, Thierry Martin11, Nadine Magy12, Sabine Berthier13, Laurent Arnaud14, Abderrahmane Bourredjem15 and Zahir Amoura16, 1Service de Médecine Interne et Maladies Systémiques, CHU de Dijon, Dijon, France, 2Clinical epidemiology, Clinical investigation center, INSERM CIC-EC 1432, Dijon University Hospital, 21000 Dijon, France, 3Médecine interne, Hôpitaux Privés de Metz, Metz, France, 4CHU de Nancy, Vascular Medicine Division and Regional Competence Center For Rare Vascular And Systemic Autoimmune Diseases, Nancy, F-54000, France; Inserm, UMR_S 1116, Nancy, F-54000, France; Université de Lorraine, Nancy, F-54000, France, Nancy, France, 5CHU de Nancy, Vascular Medicine Division and Regional Competence Centre For Rare Vascular And Systemic Autoimmune Diseases; and UMR_S U1116 Research Unit, Nancy, France, 6Department of Internal Medicine and Systemic Diseases, Hôpital François Mitterrand, CHU de Dijon, Dijon, France, 7CHU Pitié-Salpêtrière - Department of Internal Medicine 2. Referal center for SLE/APS, Paris, France, 8Internal medicine, Internal medicine department, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France, 9Internal medicine departement, Colmar Hospital, Colmar, France, 10Internal Medicine, Internal medicine departement, CHU de Reims, Reims, France, 11Cnrs UPR9021, Department of Clinical Immunology and Internal Medicine, Strasbourg University Hospital, IBMC CNRS UPR9021, Strasbourg, France, 12Internal Medecine, CHRU Besançon, Besancon, France, 13Department of Internal Medicine and Clinical Immunology, Dijon University Hospital, Dijon, France, 14Department of Medicine, Rheumatology Unit, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 15Clinical investigation center, INSERM CIC-EC 1432, Dijon University Hospital, Dijon, France, 16Université Pierre et Marie Curie, Paris, France

    Background/Purpose: To analyze variables associated with evolution of disease-specific health related quality of life (HRQoL) in systemic lupus erythematosus (SLE) patients. Methods: We conducted a…
  • Abstract Number: 1397 • 2018 ACR/ARHP Annual Meeting

    Item Responses to Disease-Specific Quality of Life Questionnaires in the 18 Months Following a Flare in SLE: An Item Response Theory Analysis of a French Prospective Longitudinal Multicenter Study

    Marie Corneloup1, Francois Maurier2, Denis Wahl3, Geraldine Muller4, Olivier Aumaître5, Pascal Sève6, Gilles Blaison7, Jean-Loup Pennaforte8, Thierry Martin9, Nadine Magy10, Sabine Berthier11, Laurent Arnaud12, Abderrahmane Bourredjem13, Zahir Amoura14 and Hervé Devilliers15, 1Clinical epidemiology, Clinical investigation center, INSERM CIC-EC 1432, Dijon University Hospital, 21000 Dijon, France, 2Médecine interne, Hôpitaux Privés de Metz, Metz, France, 3CHU de Nancy, Vascular Medicine Division and Regional Competence Centre For Rare Vascular And Systemic Autoimmune Diseases; and UMR_S U1116 Research Unit, Nancy, France, 4Department of Internal Medicine and Systemic Diseases, Hôpital François Mitterrand, CHU de Dijon, Dijon, France, 5Division of internal Medicine, Centre Hospitalier Universitaire, Hôpital Gabriel Montpied, Clermont–Ferrand, Clermont–Ferrand, France, 6Internal medicine, Internal medicine department, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France, 7Internal medicine departement, Colmar Hospital, Colmar, France, 8Internal Medicine, Internal medicine departement, CHU de Reims, Reims, France, 9Internal medicine and clinical immunology departement, Strasbourg University Hospital, Strasbourg, France, 10Internal Medecine, CHRU Besançon, Besancon, France, 11Department of Internal Medicine and Clinical Immunology, Dijon University Hospital, Dijon, France, 12Department of Rheumatology, Hôpitaux Universitaires de Strasbourg; INSERM UMR-S 1109, Strasbourg, France, 13Clinical investigation center, INSERM CIC-EC 1432, Dijon University Hospital, Dijon, France, 14Department of Internal Medicine, National referral center for systemic lupus erythematosus and anti-phospholipid syndrome, Pitie-Salpetriere University Hospital, Paris, France, 15Service de Médecine Interne et Maladies Systémiques, CHU de Dijon, Dijon, France

    Background/Purpose: To explore, at an item-level, the effect of disease activity (DA) on disease specific health related quality of life (HRQoL) factors in systemic lupus…
  • Abstract Number: 1398 • 2018 ACR/ARHP Annual Meeting

    Inflammatory Arthritis DMARD Adverse Effects Are Pervasive and Can Greatly Impact Quality of Life and Work and Social Roles: Initial Results from the Omeract Safety Working Group

    Kathleen M. Andersen1, Ayano Kelly2, Anne Lyddiatt3, Clifton O. Bingham III4, Vivian P. Bykerk5, Marita Cross6, Adena Batterman7, Joan Westreich8, Lyn March9, Michelle Jones10, Beverly Shea11, Peter Tugwell12, Peter Brooks13, Lee S. Simon14, Robin Christensen15 and Susan J. Bartlett16, 1Department of Family Medicine, McGill University, Montreal, QC, Canada, 2Centre for Kidney Research, The Children's Hospital at Westmead, Sydney, Australia, 3Musculoskeletal Group, Cochrane Collaboration, Hamilton, ON, Canada, 4Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 5Deptartment of Rheumatology, Hospital for Special Surgery, New York, NY, 6Institute of Bone and Joint Research–Kolling Institute, University of Sydney, Sydney, Australia, 7Social Work Programs, Hospital for Special Surgery, New York, NY, 8Department of Social Work Programs, Hospital for Special Surgery, New York, NY, 9Department of Rheumatology, Northern Clinical School, Institute of Bone and Joint Research, Kolling Institute, University of Sydney & Department of Rheumatology, Royal North Shore Hospital, St Leonards, Sydney, Australia, 10Johns Hopkins University School of Medicine, Baltimore, MD, 11University of Ottawa, Ottawa, ON, Canada, 12Center For Global Health, Institute of Population Hlth, Ottawa, ON, Canada, 13The University of Melbourne, Victoria, Australia, 14SDG LLC Consulting, West Newton, MA, 15Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg, Denmark, 16Department of Medicine, Division of ClinEpi, Rheumatology, Respirology, McGill University, Montreal, QC, Canada

    Background/Purpose: There is suboptimal reporting of adverse events (AE) in trials. The OMERACT Safety Working Group is developing a patient-centered AE collection and reporting approach…
  • Abstract Number: 1399 • 2018 ACR/ARHP Annual Meeting

    Assessing a Conceptual Framework of Quality of Life in a Cutaneous Lupus Erythematosus Population

    Motolani E. Ogunsanya1, Andrew Hudson2, Rebecca Vasquez3 and Benjamin F. Chong3, 1College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2Texas Tech University Health Sciences Center, Lubbock, TX, 3Dermatology, University of Texas Southwestern Medical Center, Dallas, TX

    Background/Purpose: In order to better discern medication efficacy for CLE, a better understanding of CLE’s impact on quality of life (QoL) in individuals with CLE…
  • Abstract Number: 1400 • 2018 ACR/ARHP Annual Meeting

    Effects of Childhood-Onset SLE on Academic Achievements and Employment in Adult Life

    Noortje Groot1, Marc Bijl2, Radboud J. E. M. Dolhain3, Els J. Zirkzee4, Ruth D.E. Fritsch-Stork5, Y.K. Onno Teng6, Karina de Leeuw7, Irene E.M. Bultink8 and Sylvia S.M. Kamphuis9, 1Paediatric Rheumatology, Erasmus Medical Centre - Sophia Children's Hospital, Rotterdam, Netherlands, 2Internal Medicine and Rheumatology, Martini Hospital, Groningen, Netherlands, 3Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, 4Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, 5Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 6Department of Nephrology, Leiden University Medical Center, Leiden, the Netherlands, Leiden, Netherlands, 7Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, 8Rheumatology, Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, 9Pediatric Rheumatology, Sophia Children's Hospital – Erasmus University Medical Center, Rotterdam, Netherlands

    Background/Purpose: To investigate the effects of cSLE on education, vocation and employment in a large cohort of adults with cSLE. Methods: Patients were seen by…
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