ACR Meeting Abstracts

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  • Abstract Number: 1371 • 2018 ACR/ARHP Annual Meeting

    Systemic Exposure of Triamcinolone Acetonide Following Bilateral Injection of Extended-Release Triamcinolone Acetonide and Standard Triamcinolone in Patients with Bilateral Knee Osteoarthritis

    Alan J. Kivitz1, Louis Kwong2, Tammi Shlotzhauer3, Joelle Lufkin4, Teresa Curto5 and Scott Kelley4, 1Altoona Center for Clinical Research, Duncansville, PA, 2Department of Orthopaedic Surgery, Harbor-UCLA Medical Center, Torrance, CA, 3Rochester Clinical Research, Inc., Rochester, NY, 4Flexion Therapeutics, Inc., Burlington, MA, 5Cytel Inc., Waltham, MA

    Background/Purpose: Current ACR guidelines recommend the use of IACS for short-term acute pain relief in patients (pts) with knee OA.1 Bilateral knee OA can occur…
  • Abstract Number: 1372 • 2018 ACR/ARHP Annual Meeting

    An Analysis of the Quality and Readability of Online Osteoarthritis Information with Historical Comparison

    Kieran Murray1, Tim Murray2, Anna O'Rourke3, Candice Low4 and Douglas J. Veale4, 1Rheumatology, Saint Vincent's University Hospital, Dublin 4, Ireland, 2Beaumont Hospital, Dublin, Ireland, 3Saint Vincent's University Hospital, Dublin 4, Ireland, 4Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, University College Dublin, Dublin, Ireland

    Background/Purpose: OA is the most common cause of disability in people >65 years old.Most patients in the USA use the internet for healthcare information. The…
  • Abstract Number: 1373 • 2018 ACR/ARHP Annual Meeting

    Predictive Probabilities Are Superior in Communicating the Clinical Relevance of Cartilage Thickness As an Imaging Biomarker of Knee Osteoarthritis Progression

    C. Kent Kwoh1,2, Erin L. Ashbeck1, Edward J. Bedrick3 and Felix Eckstein4,5, 1University of Arizona Arthritis Center, Tucson, AZ, 2Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, 3Department of Epidemiology and Biostatistics, University of Arizona, Tucson, AZ, 4Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria, 5Chondrometrics GmbH, Ainring, Germany

    Background/Purpose: Establishing a threshold of clinically important cartilage loss is of great interest for the design and interpretation of knee OA trials of structure-modifying treatments.…
  • Abstract Number: 1374 • 2018 ACR/ARHP Annual Meeting

    The Relationship between Loneliness and Osteoarthritis in US Adults from a Nationally Representative Survey

    Adeela Cheema1, Louise Hawkley2, Kristen Wroblewski3 and Kichul Ko4, 1Section of Geriatrics and Palliative Medicine, Department of Medicine, University of Chicago, Chicago, IL, 2NORC, University of Chicago, Chicago, IL, 3Department of Public Health Sciences, University of Chicago, Chicago, IL, 4Section of Rheumatology, Department of Medicine, University of Chicago, Chicago, IL

    Background/Purpose: Loneliness in adults is a growing phenomenon across the Western world. It is associated with increased mortality, depression, coronary heart disease and stroke. Moreover,…
  • Abstract Number: 1375 • 2018 ACR/ARHP Annual Meeting

    Comparative Safety of Flavocoxid (Limbrel) Versus Nsaids Among Osteoarthritis Patients

    Justin K Owensby1, Fenglong Xie1, Lang Chen1 and Jeffrey R. Curtis2, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama, Birmingham, AL

    Background/Purpose: Flavocoxid is a medical food formulated to assist in the management of patients with osteoarthritis (OA). Safety concerns based on case reports have been…
  • Abstract Number: 1376 • 2018 ACR/ARHP Annual Meeting

    The Omeract-Oarsi Core Set of Outcome Domains to Measure in Clinical Trials for People with Hip and/or Knee Osteoarthritis

    Toby O Smith1, Gillian Hawker2, David J. Hunter3, Lyn March4, Beverly Shea5, Robin Christensen6, Francis Guillemin7, Caroline Terwee8, Paula Williamson9, Ewa M. Roos10, Richard Loeser11, Thomas J. Schnitzer12, Margreet Kloppenburg13, Tuhina Neogi14, Christoph Ladel15, Ulrike Kaiser16, Ali Mobasheri17, Nigel K Arden1, Marc C. Hochberg18, Alan Tennant19, Maarten de Wit20, Peter Tugwell21 and Philip G. Conaghan22, 1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2University of Toronto, Toronto, ON, Canada, 3University of Sydney, Sydney, Australia, 4Department of Rheumatology, Northern Clinical School, Institute of Bone and Joint Research, Kolling Institute, University of Sydney & Department of Rheumatology, Royal North Shore Hospital, St Leonards, Sydney, Australia, 5Bruyere Research Institute, Ottawa, ON, Canada, 6Department of Rheumatology, Musculoskeletal Statistics Unit: The Parker Institute, Bispebjerg and Frederiksberg Hospital, & Department of Rheumatology, Odense University Hospital, Copenhagen, Denmark, 7University of Lorraine, Nancy, France, Nancy, France, 8Dep of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 9University of Liverpool, Liverpool, United Kingdom, 10Inst Sports and Biomechanics, University of Southern Denmark, Odense, Denmark, 11Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 12Northwestern University, Chicago, IL, 13Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands, 14Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 15Merck KGaA, Darmstadt, Germany, 16Universitätsklinikum Carl Gustav Carus Dresden, Dresden, Germany, 17Rheumatology, School of Veterinary Medicine, University of Surrey, Guildford, United Kingdom, 18University of Maryland School of Medicine, Baltimore, MD, 19Swiss Paraplegic Research, Nottwil, Switzerland, 20EULAR standing committee of PARE, Zurich, Switzerland, 21Center For Global Health, Institute of Population Hlth, Ottawa, ON, Canada, 22Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds, United Kingdom, Leeds, United Kingdom

    Background/Purpose: It has been over 20 years since the OMERACT core outcome set (COS) to measure in clinical trials with people who have hip and/or…
  • Abstract Number: 1377 • 2018 ACR/ARHP Annual Meeting

    Knee Osteoarthritis Symptom Duration Is Associated with Conditioned Pain Modulation and Vibration Perception Threshold Impairment

    Kharma C. Foucher1, Samuel Chmell2 and Carol Courtney3, 1Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, 2Orthopedic Surgery, University of Illinois at Chicago, Chicago, IL, 3Physical Therapy, University of Illinois at Chicago, Chicago, IL

    Background/Purpose: Impaired descending pain inhibition has been observed in people with knee OA and may be associated with development of chronic pain as well as…
  • Abstract Number: 1378 • 2018 ACR/ARHP Annual Meeting

    Validation of a Spanish Version of the Functional Index for Hand Osteoarthritis (FIHOA)

    Belén Barrios1, Julia Sosa2, Silvia Beatriz Papasidero3, María Alejandra Medina4, Diana Silvia Klajn5, José Ángel Caracciolo4, Julieta Giantinoto6, Florencia Pelagagge6 and María Gabriela Battaglia6, 1Rheumatology section, Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, 2Rheumatology Section, Hospital General de Agudos Dr. Enrique Tornú, Argentina, CABA, Argentina, 3Rheumatology Section, Hospital General de Agudos Dr. Enrique Tornú, Argentina, Buenos Aires, Argentina, 4Rheumatology Section, Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina, 5Rheumatology Section, Hospital General de Agudos Dr. Enrique Tornú, CABA, Argentina, 6Occupational Therapy Department, Hospital General de Agudos Dr. Enrique Tornú, Buenos Aires, Argentina

    Background/Purpose: Hand Osteoarthritis (HOA) is a highly prevalent disease with important impact on the patient´s daily activity performance and quality of life. Dreiser et al.…
  • Abstract Number: 1379 • 2018 ACR/ARHP Annual Meeting

    Appraisal of the Educational Needs in Patients with Osteoarthritis Using the Educational Needs Assessment Tool Questionnaire

    Adriana Garcia Coello1, Oscar Rillo2, Alejandro Brigante Jr.3, Maritza Quintero4, Yessica Ponce5, Rolando Espinoza6, Silvia Beatriz Papasidero7, Gonzalo Rodriguez8, Julia Sosa9, María Paula Kohan9, Dora Pereira10, Dafne Capelusnik11, Lucy Heredia12, Carlos Pineda13, Margarita González de Urizar14, Ana María Sapag Durán15, Cesar Rossi16, Pedro Santos-Moreno17, Vicente Juarez18, Jorge Esquivel-Valerio19, Vianna Khoury20, Blanca Herrera Velasco21 and Renee Souto16, 1Rheumatology Section, Hospital General de agudos Dr Ignacio Pirovano, Buenos Aires, Argentina, 2Hospital General de Agudos Dr Ignacio Pirovano, Argentina, Buenos Aires, Argentina, 3Sociedad Argentina de Reumatologia, Buenos Aires, Argentina, 4Rheumatology Section, Instituto Autónomo Hospital Universitario de Los Andes, Universidad de Los Andes, Venezuela, Mérida, Venezuela, 5Rheumatology Section, Hospital Genaral de agudos Dr Ignacio Pirovano, Argentina, Buenos Aires, Argentina, 6Rheumatology Section, Instituto Nacional de Rehabilitación, Luis Guillermo Ibarra Ibarra, Mexico, Mexico, Mexico, 7Rheumatology Section, Hospital General de Agudos Dr. Enrique Tornú, Argentina, Buenos Aires, Argentina, 8Hospital General de Agudos Dr Cosme Argerich, Argentina, Buenos Aires, Argentina, 9Rheumatology Section, Hospital General de Agudos Dr. Enrique Tornú, Argentina, CABA, Argentina, 10Rheumatology Section, Hospital Dr. Ricardo Gutiérrez, Argentina, Buenos Aires, Argentina, 11Reumatology, Instituto de Rehabilitación Psicofísica, Argentina, CABA, Argentina, 12Hospital de Tercer Nivel Obrero Nº2 de la Caja Nacional de Salud, Bolivia, Cochabamba, Bolivia (Plurinational State of), 13Instituto Nacional de Rehabilitation, Mexico, Mexico, Mexico, 14Rheumatology, Hospital San Ramón, Paraguay, Ciudad del Este, Paraguay, 15Rheumatology, Hospital Universitario Japonés, Bolivia, Santa Cruz, Bolivia (Plurinational State of), 16Rheumatology Section, Cátedra de Reumatología de la Facultad de Medicina de la Universidad de la Republica, Uruguay, Montevideo, Uruguay, 17Biomab, Center for Arthritis, Bogota, Colombia, Bogota, Colombia, 18Rheumatology Section, Hospital Señor del Milagro de Salta, Argentina, Salta, Argentina, 19Rheumatology, University Hospital “Dr. José Eleuterio González”, UANL, Mexico, Monterrey, Mexico, 20Rheumatology Section, Hospital Regional Universitario Presidente Estrella Ureña, República Dominicana, Santiago, Dominican Republic, 21Rheumatology, Centro Médico de Reumatología; Sucre, Bolivia, Sucre, Bolivia (Plurinational State of)

    Background/Purpose: The SpENAT, a Spanish version of the Educational Needs Assessment Tool (ENAT), is a self-completed questionnaire that assesses educational needs (ENs) in ostheoathritis (OA)…
  • Abstract Number: 1380 • 2018 ACR/ARHP Annual Meeting

    Complications Following Total Hip Arthroplasty in Inflammatory Versus Osteoarthritis

    Shawn Richardson1, William Schairer2, Cynthia Kahlenberg1, Thomas P. Sculco3, Peter K. Sculco3, Linda A. Russell4, Susan M. Goodman1 and Mark P. Figgie5, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, new york, NY, 3Orthopaedic Surgery, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 4Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 5Surgery, Hospital for Special Surgery, New York, NY

    Background/Purpose: THA is commonly performed in patients with a history of inflammatory arthritis. These patients are likely at higher risk of complications, from both the…
  • Abstract Number: 1381 • 2018 ACR/ARHP Annual Meeting

    Association of Omeract Core Domains of Pain and Function with Patient Satisfaction after Total Joint Replacement

    Susan M. Goodman1, Bella Y. Mehta2, Lisa A. Mandl3, Jackie Szymonifka1, Mark P. Figgie4, Iris Navarro-Millán5, Mathias Bostrom6, Michael L. Parks7, Alexander McLawhorn8, Stephen Lyman7 and Jasvinder A. Singh9, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery/Weill Cornell Medicine/Mailman School of Public Health, New York, NY, 3Rheumatology, Hospital for Special Surgery, New York, NY, 4Surgery, Hospital for Special Surgery, New York, NY, 5Weill Cornell Medicine, New York, NY, 6Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, 7Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 8Hospital for Special Surgey, New York, NY, 9Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Up to 20% of Total Joint Replacement (TJR) patients are dissatisfied, but this is difficult to study as it is challenging to pool data…
  • Abstract Number: 1382 • 2018 ACR/ARHP Annual Meeting

    Evaluating Results of an Interferon-γ Release Assay in Patients with Autoimmune Skin Disease on Hydroxychloroquine

    Rebecca Gaffney1 and Victoria P. Werth2, 1Dermatology, University of Pennsylvania, Philadelphia, PA, 2Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: QuantiFERON-TB Gold is commercial interferon-γ release assay used to screen patients for tuberculosis before starting or while on immunosuppressive therapies. Clinical studies on efficacy…
  • Abstract Number: 1383 • 2018 ACR/ARHP Annual Meeting

    Examining Cutaneous Disease Activity As an Outcome Measure for Clinical Trials in Dermatomyositis

    Rebecca Gaffney1, Meera Tarazi2, Rui Feng3, David Pearson4 and Victoria P. Werth5, 1Dermatology, University of Pennsylvania, Philadelphia, PA, 2Department of Dermatology, University of Pennsylvania, Philadelphia, PA, 3Biostatistics, Epidemiology and Informatics, University of Pennsylvania, Philadelphia, PA, 4Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, 5Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: The FDA encourages clearance of skin findings as a primary outcome of clinical trials for inflammatory skin conditions. However, some DM patients retain signs…
  • Abstract Number: 1384 • 2018 ACR/ARHP Annual Meeting

    Health-Related Quality of Life in Patients with Ankylosing Spondylitis in the United States

    W. Benjamin Nowell1, Regan Reynolds1, Kelly Gavigan1, Shilpa Venkatachalam1, Marie de la Cruz2, Emuella Flood2, Ethan Schwartz2, Beverly Romero2, Yujin Park3 and Alexis Ogdie4, 1Global Healthy Living Foundation, Upper Nyack, NY, 2ICON, Gaithersburg, MD, 3Novartis Pharmaceuticals Corporation, East Hanover, NJ, 4Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Ankylosing spondylitis (AS) is a chronic, systemic, inflammatory disease that affects primarily the sacroiliac joints and spine and can cause irreversible damage. Measuring disease…
  • Abstract Number: 1385 • 2018 ACR/ARHP Annual Meeting

    Subjective Well-Being Among Rheumatoid Arthritis Patients

    Goichi Kageyama1,2, Akira Onishi3, Yo Ueda3, Kengo Akashi3, Sho Sendo3, Jun Saegusa3 and Akio Morinobu2, 1Department of Rheumatology, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan, 2Department of Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan, 3Rheumatology and Clinical Immunology, Kobe University Graduate School of Medicine, Kobe, Japan

    Background/Purpose: Subjective well-being (SWB) is a psychological construct that is synonymous with happiness. Many variables including age, sex, income, employment, and marital status are related…
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