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  • Abstract Number: 2279 • 2019 ACR/ARP Annual Meeting

    Pregnancy in Rheumatoid Arthritis: Continue, Reduce or Stop TNF Inhibitors? A Prospective Observational Study

    Isabell Haase1, Susanna Spaethling-Mestekemper 2, Ralph Brinks 1, Matthias Schneider 3 and Rebecca Fischer-Betz 3, 1Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 2Rheumapraxis, Munich, Germany, 3Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany

    Background/Purpose: Women with active Rheumatoid Arthritis (RA) are more prone to relapses and complications during pregnancy. The potential risks of disease activation and treatment during…
  • Abstract Number: 2280 • 2019 ACR/ARP Annual Meeting

    Reproductive Health Intention Screening in Women with Systemic Rheumatic Diseases: Low Uptake and Gender-Specific Provider Patterns Following a Standardized Intervention

    Katherine Pryor1, Bill Albert 2, Susan Ritter 3, Laura Tarter 3, Jonathan Coblyn 3, Bonnie Bermas 4, Caryn Dutton 3, Lydia Pace 3, Elizabeth Janiak 3 and Candace Feldman 5, 1Brigham and Women's Hospital, Brookline, 2Power to Decide, Washington, DC, 3Brigham and Women's Hospital, Boston, 4UT Southwestern, Dallas, 5Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Reproductive health intention screening is critical in women with systemic rheumatic diseases, as both disease activity and medication use can impact pregnancy outcomes. However,…
  • Abstract Number: 2281 • 2019 ACR/ARP Annual Meeting

    The Vasculitis Pregnancy Registry (V-PREG): Information from the First 3 Years

    Jon Golenbiewski1, Kalen Young 2, Cristina Burroughs 3, Joyce Kullman 2, Peter Merkel 4 and Megan Clowse 5, 1Duke University Medical Center, Durham, NC, 2Vasculitis Foundation, Kansas City, MO, 3University of South Florida, Tampa, FL, 4University of Pennsylvania, Philadelphia, PA, 5Duke University, Durham

    Background/Purpose: As outcomes for patients with vasculitis improve and treatments become less ovarian-toxic, more women with these diseases will become pregnant. How best to manage…
  • Abstract Number: 2282 • 2019 ACR/ARP Annual Meeting

    Reproductive Counseling Documentation Practices for Women Receiving Teratogenic Medications in an Academic Rheumatology Clinic Serving a Medicaid/Medicare Patient Population

    Kimberly Showalter1, Melanie Smith 2, Jonathan Cheah 2, Nilasha Ghosh 2, Elena Gkrouzman 2, Sarah Lieber 2, Sebastian Sattui 2, Noa Schwartz 2, Monica Schwartzman 2, Jessica Berman 2, Lisa Sammaritano 2 and Anne Bass 3, 1Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York, 3Hospital for Special Surgery/Weill Cornell Medicine, New York, NY

    Background/Purpose: Women of reproductive age with rheumatic diseases are often prescribed teratogenic medications; thus, reproductive counseling is important. A prior study demonstrated improvement in counseling…
  • Abstract Number: 2283 • 2019 ACR/ARP Annual Meeting

    Improving Lactation Knowledge Among Providers Caring for Rheumatology Patients

    Brooke Mills1 and Bonnie Bermas 1, 1UT Southwestern Medical Center, Dallas, TX

    Background/Purpose: While the benefits of breastfeeding for both the mother and her infant are well established, available resources regarding medication compatibility with lactation are limited. …
  • Abstract Number: 2284 • 2019 ACR/ARP Annual Meeting

    The Titer of Anti-Double Stranded DNA Antibody Could Affect the Apgar Score of Newborns, Which Is Considered as the Predictive Clinical Index for Neurological or Physical Development

    Hiromi Shimada1, Risa Wakiya 2, Mai Mahmoud Fahmy Mansour 2, Shusaku Nakashima 2, Mikiya Kato 2, Taichi Miyagi 2, Tomohiro Kameda 2 and Hiroaki Dobashi 1, 1Kagawa University, Kagawa, Japan, 2Kagawa University, Kagawa

    Background/Purpose: Recently, the progression of treatment strategy enabled many systemic lupus erythematosus (SLE) women to become mothers. On the other hand, some reports have revealed…
  • Abstract Number: 2285 • 2019 ACR/ARP Annual Meeting

    Higher Than Expected Rates of Adverse Pregnancy Outcomes in Patients with Systemic Lupus Erythematosus from Three Tertiary Care Centers

    Ashley Blaske1, Amanda Eudy 2, Katie Kirchoff 3, Jim Oates 4, Megan Clowse 2 and April Barnado 1, 1Vanderbilt University Medical Center, Nashville, TN, 2Duke University, Durham, 3Medical University of South Carolina, Charleston, SC, 4Division of Rheumatology & Immunology/Medical University of South Carolina, Charleston, SC

    Background/Purpose: Prospective cohort studies of pregnancies managed by experts demonstrate that up to 30% of systemic lupus erythematosus (SLE) pregnancies result in preterm birth. We…
  • Abstract Number: 2286 • 2019 ACR/ARP Annual Meeting

    Mobile Responsive App – Useful Additional Tool for Data Collection in the German Pregnancy Register Rhekiss?

    Jutta Richter1, Christina Bungartz 2, Anja Weiß 3, Rebecca Fischer-Betz 4, Angela Zink 5, Matthias Schneider 1 and Anja Strangfeld 3, 1Department and Hiller Research Unit of Rheumatology, Heinrich-Heine University Duesseldorf, Duesseldorf, Nordrhein-Westfalen, Germany, 2German Rheumatism Research Center (DRFZ), Berlin, Berlin, Germany, 3German Rheumatism Research Center (DRFZ), Berlin, Germany, 4Policlinic for Rheumatology & Hiller Research Centre for Rheumatology, Heinrich-Heine-University Duesseldorf, Düsseldorf, Germany, 5German Rheumatism Research Centre and Charité University medicine, Berlin, Germany

    Background/Purpose: The German pregnancy register Rhekiss is designed as a nationwide, web-based longitudinal observational register established in 2015. The register follows women with inflammatory rheumatic…
  • Abstract Number: 2287 • 2019 ACR/ARP Annual Meeting

    Combined First-Trimester Serum BAFF and sFlt-1 Levels as an Early Biomarker of Spontaneous Abortion

    Hindi Stohl 1, Ning Yu 2 and William Stohl2, 1Harbor-UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, 2University of Southern California Keck School of Medicine, Los Angeles, CA

    Background/Purpose: Immunologic, angiogenic, and anti-angiogenic factors have been associated with spontaneous abortion (SAB), yet early identification of those pregnant women who ultimately undergo SAB remains…
  • Abstract Number: 2288 • 2019 ACR/ARP Annual Meeting

    Pregnancy Outcomes in Women Exposed to Golimumab

    Suzan Esslinger1, Susan Gabriel 2, Marijo Otero-Lobato 3, Michael Clark 4, Pamela Sheridan 4 and Anja Geldhof 5, 1Janssen Biologics BV, Leiden, Netherlands, 2Janssen Rearch & Development, LLC, Horsham, PA, 3Janssen Biologics BV, Leiden, Zuid-Holland, Netherlands, 4Janssen Research & Development, LLC, Horsham, PA, 5Janssen Research & Development, LLC, Leiden, Netherlands

    Background/Purpose: Rheumatologic disorders and inflammatory bowel disease can affect women of childbearing potential. Golimumab (GLM) is approved for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, non-radiographic…
  • Abstract Number: 2289 • 2019 ACR/ARP Annual Meeting

    Progesterone Decreases Gut Permeability Through Upregulating Occludin Expression in Primary Human Gut Tissues and Caco-2 Cells

    Zejun Zhou 1, Gary Gilkeson 2, Diane Kamen 3, Jim Oates 4 and Wei Jiang4, 1Medical University of South Carolina, Charleston, SC, 2Division of Rheumatology & Immunology/Ralph H. Johnson VA Medical Center/Medical University of South Carolina, Charleston, SC, 3Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA., Charleston, SC, 4Medical University of South Carolina, Charleston

    Background/Purpose: Progesterone plays a protective role in preventing inflammation and preterm delivery during pregnancy. However, the mechanism involved is unknown. Microbial product translocation from a…
  • Abstract Number: 2290 • 2019 ACR/ARP Annual Meeting

    A Multicentre Study of 244 Pregnancies in Women with Undifferentiated Connective Tissue Disease: Foetal/Perinatal and Maternal Outcomes and Disease Evolution Towards a Definite Connective Tissue Disease

    Massimo Radin1, Karen Schreiber 2, Irene Cecchi 1, Alessandra Bortoluzzi 3, Francesca Crisafulli 4, Cristiano M. De Freitas 5, Beatrice Bacco 1, Elena Rubini 1, Silvia Grazietta Foddai 1, Melissa Padovan 3, Silvia Gallo Cassarino 1, Franco Franceschini 6, Danieli Andrade 7, Chiara Benedetto 8, Marcello Govoni 9, Tiziana Bertero 1, Luca Marozio 1, Dario Roccatello 1, Laura Andreoli 4 and Savino Sciascia 10, 1University of Turin, Turin, Italy, 2Department of Rheumatology, Copenhagen University Hospital, Copenhagen, Denmark, 3University of Ferrara, Ferrara, Italy, 4University of Brescia, Brescia, Italy, 5Universidade de Sao Paolo, San Paolo, Brazil, 6Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy, Brescia, Italy, 7Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, Brazil, 8University of Turin, Turin, Piemonte, Italy, 9University of Ferrara, Rheumatology Unit, Ferrara, Italy, 10Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Torino, Italy

    Background/Purpose: Undifferentiated connective tissue disease(UCTD) represents a common autoimmune condition in clinical practice, however, therapeutic strategies and follow-up are mostly based on clinician expertise. Little…
  • Abstract Number: 2291 • 2019 ACR/ARP Annual Meeting

    Optimal Hydroxychloroquine Drug Levels in Pregnant Women with Systemic Lupus Erythematosus

    Stephen Balevic1, Michael Cohen-wolkowiez 2, Amanda Eudy 3, Mara Becker 4, Laura Schanberg 5 and Megan Clowse 3, 1Duke University, Hillsborough, NC, 2Duke University, Durham, NC, 3Duke University, Durham, 4Duke Children's Hospital, Durham, NC, 5Duke University Medical Center, Durham, NC

    Background/Purpose: Pregnancies in women with systemic lupus erythematosus (SLE) often result in preterm birth. Active disease during pregnancy significantly increases the risks for these poor…
  • Abstract Number: 2292 • 2019 ACR/ARP Annual Meeting

    Disease Flares of Rheumatoid Arthritis During Pregnancy: What Is the Impact of Stopping bDMARDs at the Beginning of Pregnancy?

    Maria Chiara Gerardi1, Laura Andreoli 1, Antía García-Fernández 2, Chiara Bazzani 3, MATTEO FILIPPINI 3, MICAELA FREDI 1, ROBERTO GORLA 3, Maria Grazia Lazzaroni 4, Cecilia Nalli 3, MARCO TAGLIETTI 5, SONIA ZATTI 6, ANDREA LOJACONO 6, Franco Franceschini 1 and Angela Tincani 1, 1Rheumatology and Clinical Immunology, Spedali Civili and Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy, Brescia, Italy, 2Ramon y Cajal University Hospital, Madrid, Spain, Madrid, Madrid, Spain, 3Rheumatology and Clinical Immunology, Spedali Civili, Brescia, Italy, Brescia, Italy, 4Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy., Brescia, Italy, 5[email protected], Brescia, Italy, 6Obstetrics and Gynaecology, Spedali Civili and University of Brescia, Brescia, Italy, Brescia, Italy

    Background/Purpose: During pregnancy, patients with rheumatoid arthritis (RA) can experience flares that might influence pregnancy outcomes. We aimed at assessing disease course during pregnancy and…
  • Abstract Number: 2293 • 2019 ACR/ARP Annual Meeting

    Pregnancy in Patients with Systemic Lupus Erythematosus After Cyclophosphamide Therapy

    Mitali Sen1, Anu Kurl 1, Tejal Vashi 2 and Arezou Khosroshahi 1, 1Emory University, Atlanta, GA, 2Emory University School of Medicine, Atlanta, GA

    Background/Purpose: Systemic lupus erythematosus (SLE) predominantly affects females of reproductive age. Cyclophosphamide, an alkylating agent, labelled category D for pregnancy, is used for induction in…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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