ACR Meeting Abstracts

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  • Abstract Number: 1311 • 2018 ACR/ARHP Annual Meeting

    A Multidisciplinary Cohort of Patients with Interstitial Pneumonia with Autoimmune Features

    Gabriel Schroeder1, April Barnado2, Narender Annapureddy3, Rosemarie Dudenhofer4, Leslie Crofford2 and Erin Wilfong5, 1Internal Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Division of Rheumatology and Immunology, Vanderbilt University Medical Center, Nashville, TN, 3Vanderbilt University Medical Center, Nashville, TN, 4Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, 5Division of Rheumatology and Immunology, Vanderbilt Unversity Medical Center, Nashville, TN

    Background/Purpose: Interstitial Lung Disease (ILD) remains a significant diagnostic and therapeutic challenge, especially for patients who do not meet criteria for a connective tissue disease…
  • Abstract Number: 1312 • 2018 ACR/ARHP Annual Meeting

    Interstitial Pneumonia with Autoimmune Features (IPAF)-Nsip: Hurdles to Reclassification of Overlapping Ilds

    Amaka Odonwodo1 and Aman Pande2, 1Internal Medicine, Cleveland Clinic, Cleveland, OH, 2Pulmonary Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, OH

    Background/Purpose: Interstitial lung disease (ILD) may occur in the presence of autoimmune elements without meeting criteria for a distinctive Connective Tissue Disease. The European Respiratory…
  • Abstract Number: 1313 • 2018 ACR/ARHP Annual Meeting

    Clinical Features and Timing of Studies in Interstitial Lung Disease with Autoimmune Disease Features: Do Autoantibody Panels Improve Diagnostic Yields and/or Increase Costs?

    Josephine Wright1, Dorota Odrobina2, Mary Beth Scholand1, Anne E. Tebo3 and Tracy M. Frech4, 1Internal Medicine, University of Utah, Salt Lake City, UT, 2Internal Medicine, Rheumatology, University of Utah, Salt Lake City, UT, 3Pathology, University of Utah, Salt Lake City, UT, 4Division of Rheumatology, University of Utah, Salt Lake City, UT

    Background/Purpose: The entity of interstitial lung disease with autoimmune disease features (ILD-AF) is increasingly gaining traction as condition that is best co-managed by pulmonologists and…
  • Abstract Number: 1314 • 2018 ACR/ARHP Annual Meeting

    Autoantibodies and Clinical Outcomes in Pulmonary Arterial Hypertension Associated with Connective Tissue Diseases

    Yuko Shirota1, Tomonori Ishii2, Tsuyoshi Shirai1, Hiroshi Fujii1 and Hideo Harigae1, 1Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan, 2Clinical Research, Innovation and Education Center, Tohoku University Hospital, Sendai, Japan

    Background/Purpose: Pulmonary arterial hypertension (PAH) associated with SSc (SSc-PAH) has a substantially worse prognosis as compared to other connective tissue diseases (CTD)-PAH. Although SSc-PAH are…
  • Abstract Number: 1315 • 2018 ACR/ARHP Annual Meeting

    Japanese Relapsing Polychondritis Patients with Airway Involvement Were Mutually Exclusive with Those with Ear Involvement in the Clinical Characteristics

    Jun Shimizu1 and Noboru Suzuki2, 1Department of Immunology and Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, 2Department of Immunology and medicine, St. Marianna University School of Medicine, Kawasaki-shi, 216-8511, Japan

    Background/Purpose: Relapsing polychondritis (RP) is a multisystem disorder of cartilaginous tissues. We previously found that, in a Japanese cohort study, RP patients with airway involvement…
  • Abstract Number: 1316 • 2018 ACR/ARHP Annual Meeting

    Respiratory Involvement in Relapsing Polychondritis – a Single Centre Study

    Catherine D Hughes1, Begona Lopez Garcia1, CheeKen Cheah1, Yih Jia Poh2, Shirish Sangle1 and David D'Cruz3, 1Louise Coote Lupus Unit, Guy's and St Thomas' Hospital, London, United Kingdom, 2Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore, Singapore, 3Louise Coote Lupus Unit, Guy's and St. Thomas' Hospital, London, United Kingdom

    Background/Purpose: Relapsing Polychondritis (RP) is a rare immune mediated inflammatory disorder that may result in destruction of cartilaginous tissues.  Diagnostic delay is common due to…
  • Abstract Number: 1317 • 2018 ACR/ARHP Annual Meeting

    Tracheomalacia in Coventry in UK

    Grace Pink1, Shirish Dubey2, Asad Ali1, Joanna Shakespeare3, Chris Taylor1 and Colin Gelder4, 1Respiratory medicine, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 2Rheumatology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 3Respiratory Physiology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 4University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom

    Background/Purpose: Tracheomalacia (TM) is pathological diffuse or segmental narrowing of the tracheal lumen, caused by softening of the supporting cartilage and reduction in stiffness of…
  • Abstract Number: 1318 • 2018 ACR/ARHP Annual Meeting

    Clinical Utility of Ultrasonography (US) in Diagnosing and Monitoring Disease Activity of Relapsing Polychondritis (RP) and Comparison of Cartilaginous US Findings between RP, Repeated Trauma and Healthy Subjects

    Satoshi Inotani1 and Yoshinori Taniguchi2, 1Endocrinology, Metabolism, Nephrology and Rheumatology, Kochi Medical School, Kochi, Japan, 2Endocrinology, Metabolism,Nephrology and Rheumatology, Kochi University, Kochi, Japan

    Background/Purpose: Relapsing polychondritis (RP) is a rare systemic inflammatory disorder, and the diagnosis and treatment evaluation are often difficult. Therefore, the discovery of more convenient…
  • Abstract Number: 1319 • 2018 ACR/ARHP Annual Meeting

    Familial Mediterranean Fever Related Damage Assessed By Auto-Inflammatory Disease Damage Index (ADDI) and Associated Factors with Damage

    Abdurrahman Tufan1, Berkan Armagan2, Erdal Bodakci3, Timucin Kasifoglu4, Hasan Satis5, Nuh Atas1, Alper Sari2, Hakan Babaoglu1, Gozde Yardımcı2, Reyhan Salman1, Levent Kilic2, Nazife Sule Yasar Bilge3 and Mehmet Akif Ozturk1, 1Internal Medicine-Rheumatology, Gazi University Faculty of Medicine, Ankara, Turkey, 2Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 3Rheumatology, Eskisehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey, 4Department of Internal Medicine, Division of Rheumatology, Eskisehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey, 5Rheumatology, Gazi University, Faculty of Medicine, Ankara, Turkey

    Background/Purpose: Familial Mediterranean Fever (FMF) is the most frequent auto-inflammatory disease caused by MEFV gene mutations. Although FMF is characterized by intermittent inflammatory attacks some…
  • Abstract Number: 1320 • 2018 ACR/ARHP Annual Meeting

    Activity Tracker Bracelets Captures Familial Mediterranean Fever Attacks and Their Impact on Daily Physical Activities

    Hakan Babaoglu, Ozkan Varan, Nuh Atas, Hasan Satis, Reyhan Salman, Mehmet Akif Ozturk, Berna Goker, Seminur Haznedaroglu and Abdurrahman Tufan, Internal Medicine-Rheumatology, Gazi University Faculty of Medicine, Ankara, Turkey

    Activity Tracker bracelets captures Familial Mediterranean Fever attacks and their impact on daily physical activities Background/Purpose: Familial Mediterranean fever (FMF) is a recessively inherited systemic…
  • Abstract Number: 1321 • 2018 ACR/ARHP Annual Meeting

    Clinical and Genetic Analysis of the Patients Mimicking Familial Mediterranean Fever

    Dai Kishida1, Yasuhiro Shimojima2 and Yoshiki Sekijima1, 1Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan, 2Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan

    Clinical and genetic analysis of the patients mimicking familial Mediterranean feverBackground/Purpose: Familial Mediterranean fever (FMF) is an auto-inflammatory disease characterized by recurrent episodes of fever…
  • Abstract Number: 1322 • 2018 ACR/ARHP Annual Meeting

    Comparison of Serum Hepcidin and Calprotectin Levels in Patients with Familial Mediterranean Fever (FMF) and Healthy Subjects

    Gökmen ASAN1, Mehmet Emin DERİN2, Halef Okan DOĞAN3, Meliha BAYRAM4, Mehtap ŞAHİN3 and Ali Şahin5, 1İnternal medicine, Cumhuriyet University Medical Faculty, sivas, Turkey, 2Rheumatology-internal medicine, Cumhuriyet University Medical Faculty, sivas, Turkey, 3Biochemistry, Cumhuriyet University Medical Faculty, sivas, Turkey, 4internal medicine, Cumhuriyet University Medical Faculty, sivas, Turkey, 5Department of Rheumatology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey

    Background/Purpose: Familial Mediterranean fever (FMF) is an autoinflammatory disease which has self-limiting inflammatory attacks placing in polyserositis. Hepcidin is a protein in peptide structure and…
  • Abstract Number: 1323 • 2018 ACR/ARHP Annual Meeting

    Evaluation of Prolidase and HIF-1α Levels in Patients with Familial Mediterranean Fever (FMF)

    Meliha BAYRAM1, Mehmet Emin DERİN2, Halef Okan DOĞAN3, Gökmen ASAN4, Mehtap ŞAHİN3 and Ali Şahin5, 1internal medicine, Cumhuriyet University Medical Faculty, sivas, Turkey, 2Rheumatology-internal medicine, Cumhuriyet University Medical Faculty, sivas, Turkey, 3Biochemistry, Cumhuriyet University Medical Faculty, sivas, Turkey, 4İnternal medicine, Cumhuriyet University Medical Faculty, sivas, Turkey, 5Department of Rheumatology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey

    Background/Purpose: Familial Mediterranean Fever(FMF) is an autoinflammatory disease characterized by recurrent fever attacks, sterile peritonitis, pleural inflammation, arthritis and / or  erysipelas like rash. Prolidase…
  • Abstract Number: 1324 • 2018 ACR/ARHP Annual Meeting

    Anakinra Treatment in Refractory Cases of Adult-Onset Still Disease: Case Series

    Serdal Ugurlu1, Berna Yurttas1, Gul Guzelant1, Bilgesu Ergezen2 and Huri Ozdogan3, 1Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 2Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 3Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose: Despite methotrexate and steroid treatment, in cases of Adult-onset Still’s disease (AOSD) it is usually difficult to maintain clinic stability. In refractory cases, Anakinra…
  • Abstract Number: 1325 • 2018 ACR/ARHP Annual Meeting

    Canakinumab Treatment in Adult-Onset Still’s Disease: Case Series

    Serdal Ugurlu1, Gul Guzelant1, Berna Yurttas1, Bilgesu Ergezen1, Ediz Dalkiliç2, Timucin Kasifoglu3, Burcu Yagız4 and Huri Ozdogan1, 1Istanbul University, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 2Department of Internal Medicine, Division of Rheumatology, Uludağ University Faculty of Medicine, Bursa, Turkey, 3Department of Internal Medicine, Division of Rheumatology, Eskisehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey, 4Uludag University, Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Bursa, Turkey

    Background/Purpose: In Adult-onset Still’s disease (AOSD), cases refractory to typical DMARDs, Canakinumab (an anti-IL-1ß monoclonal antibody) has been reported to be effective in a limited…
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