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  • Abstract Number: 1233 • ACR Convergence 2025

    Synovial Joint Transcriptomic Differences in Individuals with Knee Osteoarthritis and Neuropathic Pain Symptomology

    Joseph Lesnak1, Michael Zuscik2, Michael Dayton2, Craig Hogan2, Prabil Kaini2, Andrew Clauw3, Jennifer Seifert4, Michael Clay5, Theodore Price1 and Larry Moreland6, 1University of Texas at Dallas, Dallas, 2University of Colorado School of Medicine, Aurora, 3Univ of Colorado, Aurora, CO, 4University of Colorado and Oklahoma Medical Research Foundation, Aurora, CO, 5University of Colorado, Aurora, CO, 6University of Colorado, Denver, CO

    Background/Purpose: Osteoarthritis (OA) is a painful disease of the synovial joint and is the most common form of arthritis with a large global burden. A…
  • Abstract Number: 1250 • ACR Convergence 2025

    Patient Perceptions of the National Tele-Rheumatology Program: A Mixed Methods Study

    Alicia Hamblin1, Catherine Nasrallah2, Cherish Wilson3, Bernard Ng4 and gabriela Schmajuk5, 1UCSF, San Francisco, CA, 2University of California San Francisco (UCSF), San Francisco, CA, 3UCSF / SFVA, San Francisco, CA, 4Lexington VA, University of Washington, Seattle, 5University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, CA

    Background/Purpose: The national shortage of rheumatology clinicians disproportionately affects over 2.7 million rural Veterans with already limited access to healthcare. To address this gap, the…
  • Abstract Number: 1000 • ACR Convergence 2025

    A Deep-Learning Based Approach Uncovers Novel Mediators of Micro-RNA Restraint of Type-2 Immunity

    Shaan Sekhon1, Robin Kageyama2, Neil Sprenkle3, Hannah Happ2, Eric Wigton2, Heather Pua3 and Mark Ansel2, 1University of California, San Francisco, Berkeley, 2University of California, San Francisco, San Francisco, 3Vanderbilt University, Nashville

    Background/Purpose: MicroRNAs, such as miR-24 and miR-27, co-expressed within the Mirc11 and Mirc22 clusters, orchestrate a regulatory network critical to Th2 cell differentiation and cytokine…
  • Abstract Number: 1236 • ACR Convergence 2025

    Vestibulocortical Stimulation via Caloric Irrigation in Nociplastic Disease: Therapeutic Effects on Pain, Autonomic Functioning & Quality of Life Measures

    Michael Kaplan1, Alexandra Canori2, Rebecca Howard2, Talia Torkian3, Rebecca Pietro1, Gabriela Santiago-Pichardo1, Daniel Clauw4, David Putrino2, Yousaf Ali1, Laura Tabacof2 and Trung Ngo5, 1Division of Rheumatology, Mount Sinai Hospital, New York, 2Department of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, 3Division of Rheumatology, Icahn School of Medicine at Mount sinai, New York, 4Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, 5RECOVER Injury Research Centre, The University of Queensland and Surgical, Treatment & Rehabilitation Service (STARS), Queensland, Australia

    Background/Purpose: Fibromyalgia (FM) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are prototypical nociplastic disorders marked by centralized pain & fatigue, respectively. Nociplastic symptoms — such as…
  • Abstract Number: 1157 • ACR Convergence 2025

    Safety and Tolerability of a Recombinant Zoster Vaccine in Patients with Inflammatory Rheumatic Musculoskeletal Diseases: A Prospective Longitudinal Study over 12 Months

    Ella Steiner1, Ioana Andreica2, Stefanie Reale3, Gianna Chierego4, Philipp Köhler5, Sonja Zapke4, Benjamin Wilde6, David Kiefer7, Philipp Sewerin2, Hilal Kavruk5, Dimitra Karagkiozidou5, Panagiotis Ermeidis5, Barbara Guminski5, Andreas Kribben6, Jürgen Braun8, Xenofon Baraliakos9 and Uta Kiltz9, 1Rheumazentrum Ruhrgebiet Herne, Herne, Nordrhein-Westfalen, Germany, 2Rheumazentrum Ruhrgebiet Herne; Ruhr-Universität Bochum, Germany, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Nordrhein-Westfalen, Germany, 4Rheumazentrum Ruhrgebiet, Herne, Germany, 5Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 6University Hospital, Nephrology, Essen, Essen, Germany, 7Private practice of rheumatology, Hattingen, Germany, 8Ruhr-University, Bochum, Germany; and Rheumatologische Versorgungszentrum (RVZ) Steglitz, Berlin, Germany, 9Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany

    Background/Purpose: Herpes zoster (HZ) is common among older adults, with a lifetime risk of 25%. The risk is particularly increased in individuals with immunosuppression such…
  • Abstract Number: 1134 • ACR Convergence 2025

    Efficacy and Safety of Anakinra for Acute Calcium Pyrophosphate Deposition Disease Flare: A Systematic Review and Meta-Analysis

    Pannathorn Nakaphan1, Somkiat Phutinart2, Patavee Pajareya2, Priabprat Jansem3, Nattanicha Chaisrimaneepan4, Pim Jetanalin5 and Noppachai Siranart2, 1Department of Internal Medicine, Weiss Memorial Hospital, Chicago, IL, 2Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand, 3Department of Psychiatry, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand, 4Department of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, 5Department of Medicine, Division of Rheumatology, University of Illinois College of Medicine, Chicago, IL

    Background/Purpose: Calcium Pyrophosphate Deposition Disease (CPPD) is a common inflammatory arthritis among older adults. Comorbidities often limit conventional treatment of acute CPPD flare. Anakinra, an…
  • Abstract Number: 1137 • ACR Convergence 2025

    Increased Risk of Cardiovascular Events and Mortality Related to Diffuse Idiopathic Skeletal Hyperostosis (DISH): A Systematic Review and Meta-Analysis

    Pitchaporn Yingchoncharoen1, Nattanicha Chaisrimaneepan2, Miriam Paz3, Chanokporn Puchongmart1, Ben thiravetyan1, Panat Yanpiset1 and Jerapas Thongpiya4, 1Texas Tech Health Sciences Center, Lubbock, TX, 2Department of Medicine, Texas Tech University Health Sciences Center, Lubbock, TX, 3Texas Tech University Health Sciences Center, Lubbock, 4Texas Tech University Health Sciences Center at Lubbock Program, Lubbock, TX

    Background/Purpose: Diffuse Idiopathic Skeletal Hyperostosis (DISH) is characterized by ossification and calcification of the entheses with prevalence increasing with age. It has been reported to…
  • Abstract Number: 1243 • ACR Convergence 2025

    Broad Cytokine Dysregulation in Fibromyalgia Patients: A Pilot Immune Profiling Study

    Robert Katz1 and Alexandra Katz Small2, 1Rush University Medical Center, Chicago, IL, 2Rheumatology Associates, CHICAGO, IL

    Background/Purpose: Fibromyalgia is a chronic pain syndrome characterized by widespread musculoskeletal pain, fatigue, cognitive disturbances, and poor sleep. Despite accumulating evidence of immune involvement, a…
  • Abstract Number: 1010 • ACR Convergence 2025

    Confounding by Indication in Observational Studies Investigating Glucocorticoid-Associated Adverse Events in Patients with Rheumatoid Arthritis: A Systematic Literature Review

    Andriko Palmowski1, Anne Elisabeth Beenken2, Anne Pankow2, Judith Oldenkott2, Henriette Käding2, Edgar Wiebe3, Zhivana Boyadzhieva4, Eric L Matteson5, Ioanna Minopoulou6, Thorben Witte2, David Simon7, Arnd Kleyer6 and FRANK BUTTGEREIT8, 1Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 2Charité, Berlin, Germany, 3Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, Berlin, Berlin, Germany, 4Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Berlin, Germany, 5Mayo Clinic College of Medicine and Science, Rochester, MN, 6Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, Berlin, Germany, 7Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, Berlin, Germany, 8Charité University Medicine Berlin, Berlin, Berlin, Germany

    Background/Purpose: Observational studies investigating glucocorticoids (GCs) and related adverse events (AEs) in patients with rheumatoid arthritis (RA) can suffer from bias by indication if confounders…
  • Abstract Number: 1245 • ACR Convergence 2025

    Efficacy And Safety of Low-dose Naltrexone In Fibromyalgia: An Updated Systematic Review And Meta-Analysis of Randomized Controlled Trials (RCTs)

    Rubab Rizwan, Sehneet Grewal, Sri Varsha Banda and Mohammad Hazique, Nuvance Health, poughkeepsie, NY

    Background/Purpose: Fibromyalgia is a chronic condition marked by widespread pain that can significantly reduce a patient’s quality of life. While low-dose naltrexone (LDN) has emerged…
  • Abstract Number: 1144 • ACR Convergence 2025

    A quantitative study of renal medulla echogenicity in 250 Vietnames gout patients shows correlation with poor renal function

    Thomas Bardin1, Quang Nguyen2, anouk Walter-Petrich3, Khoi Minh Tran2, Duong Ba Pham2, Quang Huy Nguyen4, Chuc Van Tran2, Day Phuoc Huynh2, Minh Do5, Emmanuel Letavernier6, richette pascal7, Matthieu Resche-Rigon3 and Jean-Michel Correas8, 1Lariboisiere Hospital, Department of Rheumatology, Paris, France, 2Vien Gut Medical centre, Ho Chi Minh City, Vietnam, 3UMR U1342 ECSTRA team INERM, Université Paris Cité, Paris, France, 4Vien Gut Medicfal Centre, Ho Chi Minh City, 5University of Medicine and Pharmacy at Ho Chi Min City, Ho Chi Minh City, Vietnam, 6Sorbonne Université and INSERM, UMR S 1155, Hôpital Tenon, Paris, France, 7Rheumatology Department, Lariboisiere Hospital, Paris, Ile-de-France, France, 8Department of Radiology, NeckerUniversity Hospital, Paris, France

    Background/Purpose: We previously described the frequent occurrence of an hyperechogenic pattern of the renal medulla following crystal deposition in untreated Vietnamese patients with severe tophaceous…
  • Abstract Number: 1252 • ACR Convergence 2025

    Can LLMs Categorize Patient Priorities Like Humans? Comparing AI and Human Coders in Arthritis Nominal Group Discussions

    Melissa Mannion1, Bryce Thornton1, Bella Mehta2, Ronan O'Beirne1, Emily Smitherman1, Livie Timmerman3, Shilpa Venkatachalam4, Jeffrey Curtis1 and John Osborne1, 1University of Alabama at Birmingham, Birmingham, AL, 2Hospital for Special Surgery, Weill Cornell Medicine, Jersey City, NJ, 3University of Alabama at Birmingham, Gardendale, AL, 4Global Healthy Living Foundation, New York, NY

    Background/Purpose: Identifying informational needs of individuals with inflammatory arthritis is critical to enhancing communication and supporting shared decision making between patients, caregivers, and providers. However,…
  • Abstract Number: 1017 • ACR Convergence 2025

    Effectiveness of Recombinant Zoster Vaccine in Reducing Herpes Zoster Incidence and All-Cause Mortality Among Rheumatoid Arthritis Patients: A Retrospective Cohort Study of 21,046 Individuals from TriNetX U.S. Collaborative Network

    James Wei1, Shiow-Ing Wang2 and Ying-Li Lin2, 1Chung Shan Medical University Hospital, Taichung, Taichung, Taiwan (Republic of China), 2Chung Shan Medical University Hospital; China Medical University, Taichung, Taiwan (Republic of China)

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk of developing herpes zoster (HZ). This study aimed to assess the effectiveness of recombinant zoster…
  • Abstract Number: 1251 • ACR Convergence 2025

    Steroids and Me (Sam): engaging and educating steroid-treated patients via patient advocacy partnerships and internet search channels.

    Michelle Petri1, Martha Stone2, John Stone3, meredith Marinaro4, Matt Wilkinson5, Walter Lentfert6, Camille Kotton7, Jeffrey Gelfand8, Jane McDowell9 and Tricha Shivas10, 1Johns Hopkins University School of Medicine, Timonium, MD, 2Steritas, LLC, Concord, MA, 3Massachusetts General Hospital , Harvard Medical School, Concord, MA, 4Novartis, Hartford, CT, 5UpThereEverywhere, London, United Kingdom, 6UpThereEverywhere, Charlotte, NC, 7Harvard Medical School, Boston, MA, 8UCSF Department of Neurology, Mill Valley, CA, 9Queens University Belfast, Belfast, United Kingdom, 10Foundation for Sarcoidosis Research, Chicago, IL

    Background/Purpose: We report on two years of engagement with Sam, a patient-facing program to optimize the use of glucocorticoids and discontinue them when possible. We…
  • Abstract Number: 1267 • ACR Convergence 2025

    Patient Reported Outcomes Predict Subsequent Treatment Intensification Among Rheumatoid Arthritis Patients: Longitudinal PRO Measurement Using a Mobile Health App

    Leah Santacroce1, Misti Paudel2 and Daniel Solomon3, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Division of Rheumatology, Inflammation, and Immunity, Boston, MA, 3Brigham and Women's Hospital, Newton, MA

    Background/Purpose: Patient Reported Outcomes (PROs) collected via a mobile health application (App) can provide valuable insight into the health of patients with Rheumatoid Arthritis (RA).…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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