Abstracts Archive - Page 1062 of 2425 - ACR Meeting Abstracts

Abstract Number: 861 • 2018 ACR/ARHP Annual Meeting
Critical Appraisal Self-Efficacy and Learning Behavior in Rheumatology Trainees
Juliet Aizer¹, Michael D. Tiongson², Julie Schell³, Jessica R. Berman¹, Stephen A. Paget¹ and Lisa A. Mandl¹, ¹Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ²Hospital for Special Surgery, New York, NY, ³The University of Texas at Austin, Austin, TX
Background/Purpose: Critical appraisal self-efficacy, defined as confidence in one’s ability to appraise the clinical literature, may impact trainees’ ability to optimally use and incorporate literature…
Abstract Number: 862 • 2018 ACR/ARHP Annual Meeting
Addressing the Pediatric Rheumatology Workforce Shortage: Results from the American College of Rheumatology Annual Pediatric Residents Program
Sangeeta Sule¹, Jay Mehta², Nicole Bitencourt³, Ashley Cooper⁴, Jennifer Cooper⁵, Catherine Figueroa⁶, Linda Hiraki⁷, Natasha M. Ruth⁸, Marinka Twilt⁹, Julie Marie Anderson¹⁰ and Stacy P. Ardoin¹¹, ¹Pediatrics, Johns Hopkins University, Baltimore, MD, ²Rheumatology, Children’s Hospital of Philadelphia, Philadelphia, PA, ³Division of Rheumatic Diseases, UT Southwestern Medical Center, Dallas, TX, ⁴Pediatric Rheumatology, University of Missouri-Kansas City/Children's Mercy Hospital, Kansas City, MO, ⁵Pediatric Rheumatology, Univ. of California San Francisco, San Francisco, CA, ⁶Univ. of Iowa, Iowa City, IA, ⁷Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁸Rheumatology, Medical University of South Carolina, Charleston, SC, ⁹Pediatrics, University of Calgary, Calgary, AB, Canada, ¹⁰Administration & Governance, American College of Rheumatology, Atlanta, GA, ¹¹The Ohio State University Wexner Medical Center, Columbus, OH
Background/Purpose: The recent ACR Workforce Survey has projected that the current workforce shortage in pediatric rheumatology will worsen in the coming decades. Contributing to this…
Abstract Number: 863 • 2018 ACR/ARHP Annual Meeting
Combining Cardiac Magnetic Resonance and Right Heart Catheterization to Evaluate Right Ventricular Function for the Prognosis Prediction in Patients with Connective Tissue Diseases and Pulmonary Hypertension
Nobuya Abe¹, Masaru Kato², Hiroyuki Nakamura², Atsushi Noguchi², Yuichiro Fujieda², Kenji Oku², Toshiyuki Bohgaki², Olga Amengual², Shinsuke Yasuda² and Tatsuya Atsumi², ¹Department of Rheumatology, Endocrinology and Nephrology, Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ²Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan
Background/Purpose: Pulmonary arterial hypertension associated with connective tissue diseases (CTD-PAH), particularly PAH associated with systemic sclerosis (SSc-PAH), has a poor prognosis compared with other PAH.…
Abstract Number: 864 • 2018 ACR/ARHP Annual Meeting
The Diagnostic Utility of the Relation between MRI Bone Marrow Edema and Other Types of MRI Lesions in the Sacroiliac Joints in Axial Spondyloarthritis
Sengül Seven¹, Pernille Hededal², Mikkel Østergaard³, Lone Morsel-Carlsen⁴, Inge Juul Sørensen⁵, Birthe Bonde⁶, Gorm Thamborg⁷, Oliver Hendricks⁸, Niklas Rye Jørgensen⁹ and Susanne J Pedersen¹⁰, ¹Copenhagen Center for Arthritis Research, Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Glostrup., 2600 Glostrup, Denmark, ²Dept. of Radiology, Rigshospitalet, University of Copenhagen, Glostrup., Glostrup, Denmark, ³Copenhagen Center for Arthritis Research, Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Glostrup., Glostrup, Denmark, ⁴Department of Radiology, Bispebjerg-Frederiksberg Hospital, Copenhagen, Copenhagen, Denmark, ⁵Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Glostrup, Glostrup, Denmark, ⁶Birthe Bonde Clinic of Physiotherapy, Copenhagen, Denmark, ⁷Copenhagen Center for Arthritis Research, Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark, ⁸King Christian 10th Hospital for Rheumatic Diseases, University of Southern Denmark, Institute of Regional Health Research, Graasten, Denmark, ⁹Dept. of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Glostrup, Glostrup, Denmark, ¹⁰Copenhagen Center for Arthritis Research, Dept. of Rheumatology, Rigshospitalet, University of Copenhagen, Glostrup, Glostrup, Denmark
Background/Purpose: MRI detected bone marrow edema (BME) plays a central role in the ASAS (Assessment of Spondyloarthritis International Society) classification criteria for axial spondyloarthritis (axSpA).…
Abstract Number: 865 • 2018 ACR/ARHP Annual Meeting
Structural and Microstructural Intraarticular Bone Changes at the Metacarpal Heads in Patients with Psoriatic Arthritis Compared to Controls: A HR-pQCT Study
Dongze Wu¹, James F Griffith², Steven H.M. Lam¹, Jiang Yue¹, Priscilla Wong¹, Lin Shi³, Edmund Li¹, Isaac T. Cheng¹, Tena K. Li¹, Tracy Y. Zhu⁴, Vivian W. Hung⁴, Ling Qin⁵ and Lai-Shan Tam⁶, ¹Department of Medicine & Therapeutics, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, Hong Kong, China, ²Department of Imaging and Interventional Radiology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, ³Research Centre for Medical Image Computing, Department of Imaging and Interventional Radiology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, ⁴Bone Quality and Health Centre of the Department of Orthopedics & Traumatology, The Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China, ⁵Bone Quality and Health Centre of the Department of Orthopedics & Traumatology, The Chinese University of Hong Kong, Hong Kong, Hong Kong, ⁶Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Background/Purpose: Metacarpal head directly exposed to intra-articular inflammatory milieu, therefore may lead to abnormal bone remodeling (bone loss and new bone formation). The aims of…
Abstract Number: 866 • 2018 ACR/ARHP Annual Meeting
Patterns of Monosodium Urate Deposition on Dual-Energy CT in Gout Patients on Urate-Lowering Therapy
Chio Yokose¹, Yuqing Zhang², Nicola Dalbeth³, Jie Wei¹, Savvas Nicolaou⁴, Scott Baumgartner⁵, Jia Hu⁶, Maple Fung⁵ and Hyon K. Choi¹, ¹Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, ²Department of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, ³University of Auckland, Auckland, New Zealand, ⁴Radiology, University of British Columbia, Vancouver, BC, Canada, ⁵Formerly Ardea Biosciences, San Diego, CA, ⁶Heron Therapeutics, San Diego, CA
Background/Purpose: Gout is typically characterized as an acute monoarthritis involving the joints of the foot. However, polyarticular involvement develops, especially in advanced disease. Patterns of…
Abstract Number: 867 • 2018 ACR/ARHP Annual Meeting
An MRI Guided Treat-to-Target Strategy in Rheumatoid Arthritis Patients in Clinical Remission Improved MRI Inflammation but Not Damage Progression – Results from the Imagine-RA Randomized Controlled Trial
Signe Møller-Bisgaard¹, Kim Hørslev-Petersen², Bo Jannik Ejbjerg³, Daniel Glinatsi⁴, Merete Lund Hetland¹, Lykke Ørnbjerg¹, Jakob M. Møller⁵, Mikael Boesen⁶, Robin Christensen⁷, Kristian Stengaard-Pedersen⁸, Ole Rintek Madsen⁹, Bente Jensen¹⁰, Jan Alexander Villadsen¹¹, Ellen-Margrethe Hauge⁸, Philip Bennett¹², Oliver Hendricks², Karsten Asmussen¹³, Marcin Ryszard Kowalski¹⁴, Hanne Lindegaard¹⁵, Sabrina Mai Nielsen⁷, Henning Bliddal¹⁶, Niels Steen Krogh¹⁷, Torkell Ellingsen¹⁵, Agente Nielsen¹⁸, Lone Balding¹⁹, Anne Grethe Jurik²⁰, Henrik S Thomsen¹⁹ and Mikkel Østergaard²¹, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ²King Christian 10th Hospital for Rheumatic Diseases, University of Southern Denmark, Institute of Regional Health Research, Graasten, Denmark, ³Department of Rheumatology, Zealand University Hospital, Køge, Denmark, ⁴Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark, ⁵Dept. of Radiology, Copenhagen University Hospitals, Herlev and Gentofte, Copenhagen, Denmark, ⁶Department of Radiology, Bispebjerg-Frederiksberg Hospital, Copenhagen, Copenhagen, Denmark, ⁷Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg, Denmark, ⁸Department of Rheumatology, Aarhus University Hospital, Department of Clinical Medicine, Aarhus, Denmark, ⁹Department of Rheumatology, Copenhagen University Hospital, Herlev and Gentofte, Hellerup, Denmark, ¹⁰Department of Rheumatology, Frederiksberg Hospital, Copenhagen, Denmark, Copenhagen, Denmark, ¹¹Department of Rheumatology, Silkeborg Hospital, Silkeborg, Denmark, ¹²Department of Rheumatology, Copenhagen University Hospital, Herlev and Gentofte, Copenhagen, Denmark, ¹³Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ¹⁴Department of Rheumatology, Sygehus Vendsyssel, Hjørring, Hjørring, Denmark, ¹⁵Department of Rheumatology, Odense University Hospital, Odense, Denmark, ¹⁶The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ¹⁷The DANBIO Registry, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, ¹⁸Department of Radiology, Silkeborg Hospital, Silkeborg, Denmark, ¹⁹Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark, ²⁰Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ²¹Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup Copenhagen Center for Arthritis Research, Copenhagen, Denmark
Background/Purpose: Magnetic Resonance Imaging (MRI) bone marrow edema (BME)/osteitis and MRI synovitis have been identified as predictors of structural damage progression in rheumatoid arthritis RA1,2.…
Abstract Number: 868 • 2018 ACR/ARHP Annual Meeting
International Multi-Reader Validation of the Outcome Measures in Rheumatology Hip MRI Scoring System (OMERACT HIMRISS) for Bone Marrow Lesions in Osteoarthritis
Jacob L. Jaremko¹, Robert G. Lambert², Susanne J Pedersen³, Ulrich Weber⁴, Duncan Lindsay⁵, Zeid Al-Ani⁵, Marcus Pianta⁶, Stephanie Wichuk⁷, Kieran Steer⁸, Joel Paschke⁹ and Walter P. Maksymowych¹⁰, ¹Radiology, University of Alberta, Edmonton, Canada, Edmonton, AB, Canada, ²Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ³Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark, ⁴University of Southern Denmark, Odense, Denmark, ⁵Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ⁶Rheumatology, St. Vincent's Hospital, Melbourne, Australia, ⁷Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ⁸Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ⁹CaRE Arthritis, Edmonton, Canada, Edmonton, AB, Canada, ¹⁰CaRE Arthritis, Edmonton, AB, Canada
Background/Purpose: Bone marrow lesion (BML) in hip osteoarthritis (OA) may be a determinant of prognosis and a target for emerging anti-inflammatory therapies. We developed the…
Abstract Number: 869 • 2018 ACR/ARHP Annual Meeting
Failure to Reach Serum Urate Target Is Associated with Elevated Mortality in Gout
Fernando Perez-Ruiz^1,2,3, Pascal Richette^4,5, Austin Stack⁶, Ravichandra Karra Gurunath⁷, MARIA JESUS GARCIA DE YEBENES Y PROUS⁸ and Loreto Carmona⁹, ¹Rheumatology Division, Hospital Universitario Cruces, Baracaldo, Spain, ²University of the Basque Country (UPV/EHU), Bilbao, Spain, ³BioCruces Health Research Institute, Barakaldo, Spain, ⁴Lariboisière Hospital, Lariboisière, University of Paris 7, Paris, France, ⁵Rheumatology, Université Paris Diderot, Paris, France, ⁶Nephrology, University Hospital Limerick & Health Research Institute,University of Limerick, Limerick, Ireland, ⁷Grünenthal GmbH, Aachen, Germany, ⁸Institute for Musculoskeletal Health, Madrid, Spain, ⁹Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain
Background/Purpose: Gout is associated with an increased risk of cardiovascular events and death. It has been shown that both overall and risk of death are…
Abstract Number: 870 • 2018 ACR/ARHP Annual Meeting
Patient-Reported Burden of Gout in 2017 from the United States
Puja P. Khanna¹, Douglas C.A. Taylor², An-Chen Fu² and Robert Morlock³, ¹University of Michigan, Ann Arbor, MI, ²Ironwood Pharmaceuticals, Inc., Cambridge, MA, ³YourCareChoice, Ann Arbor, MI
Background/Purpose: Gout is reported to impact 3.9% of the US adult population (Zhu. Arthritis Rheum 2011;63:3136-41). Treatment encompasses controlling acute attacks (flares) and, dependent on…
Abstract Number: 871 • 2018 ACR/ARHP Annual Meeting
Estimates of Diet Quality Explain Less Variability in Serum Urate Levels Than Genetic Factors
Tanya J. Major¹, Ruth Topless¹, Nicola Dalbeth² and Tony R. Merriman¹, ¹University of Otago, Dunedin, New Zealand, ²University of Auckland, Auckland, New Zealand
Background/Purpose: Hyperuricaemia (elevated serum urate) is a central risk factor for gout, an acute inflammatory form of arthritis. The balance between the hepatic production of…
Abstract Number: 872 • 2018 ACR/ARHP Annual Meeting
Is the Serum Uric Acid Therapeutic Target Protective of Chronic Kidney Disease, Cardiovascular Disease, and Mortality for Patients with Gout? a Longitudinal Study
Douglas C.A. Taylor¹, Dena Jaffe², Moshe Hoshen³, Galit Shefer³, Asaf Bachrach³, Becca Feldman³, An-Chen Fu¹ and Hyon K. Choi⁴, ¹Ironwood Pharmaceuticals, Inc., Cambridge, MA, ²Kantar Health, Tel Aviv, Israel, ³Clalit Research Institute, Tel Aviv, Israel, ⁴Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA
Background/Purpose: Many studies have found that serum uric acid (sUA) levels are associated with the incidence of chronic kidney disease (CKD), cardiovascular disease (CVD), and…
Abstract Number: 873 • 2018 ACR/ARHP Annual Meeting
General Safety of Febuxostat and Allopurinol in a Cardiovascular Outcomes Study in Patients with Gout
Kenneth Saag¹, Michael A. Becker², William B. White³, Andrew Whelton⁴, Jeffrey Borer⁵, Philip Gorelick⁶, Barbara Hunt⁷, Majin Castillo⁷ and Lhanoo Gunawardhana⁷, ¹University of Alabama at Birmingham, Birmingham, AL, ²University of Chicago Pritzker School of Medicine, Chicago, IL, ³Cardiology, University of Connecticut School of Medicine, Farmington, CT, ⁴Johns Hopkins University School of Medicine, Hunt Valley, MD, ⁵State University of New York Downstate Medical Center, Brooklyn, NY, ⁶Michigan State University College of Human Medicine, Grand Rapids, MI, ⁷Takeda Pharmaceuticals International, Deerfield, IL
Background/Purpose: The cardiovascular (CV) safety study CARES has the longest study duration of any randomized controlled trial in patients (pts) with gout and CV disease.…
Abstract Number: 874 • 2018 ACR/ARHP Annual Meeting
Preventing a Large Majority of Incident Gout Cases By Modifying Key Risk Factors: Findings from a Prospective Cohort of 44,629 Men over 26 Years
Sharan K. Rai^1,2, Na Lu³, Chio Yokose⁴ and Hyon K. Choi^3,4, ¹Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, ²Graduate School of Arts and Sciences, Harvard University, Cambridge, MA, ³Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, MA, ⁴Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA
Background/Purpose: Many modifiable risk factors have been found to be independently associated with the risk of developing gout, including dietary factors (e.g., intakes of red…
Abstract Number: 875 • 2018 ACR/ARHP Annual Meeting
Anti-Calreticulin Antibody – a Novel Antibody in Patients with Idiopathic Inflammatory Myopathies and Its Association with Malignancy
He Chen^1,2, Guochun Wang³ and Xin Lu⁴, ¹Department of Rheumatology, China-Japan Friendship Hospital, Beijing, China, ²Graduate School of Peking Union Medical College, Beijing, China, ³China-Japan Friendship Hospital, Beijing, China, ⁴Rheumatology, China-Japan Friendship Hospital, Beijing, China
Background/Purpose: To investigate the occurrence of anti-calreticulin antibodies (anti-CRT Abs) and evaluate its association with malignancy in patients with idiopathic inflammatory myopathies (IIM). Methods: In…

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