Abstracts Archive - Page 1060 of 2607 - ACR Meeting Abstracts

Abstract Number: 1798 • 2019 ACR/ARP Annual Meeting
Time to Bridge the Gap in Rheumatology Education: Interactive Team Based Learning Is Most Effective in Increasing Internal Medicine Residents’ Knowledge
Alysia Kwiatkowski¹, Najia Shakoor ¹, Augustine Manadan ¹, Michael Grant ¹, Joel A. Block ¹ and Sonali Khandelwal ¹, ¹Rush University Medical Center, Chicago, IL
Background/Purpose: Medical education curricula have evolved to more interactive approaches. Fully interactive, team-based learning (TBL) is a flipped classroom model that has been well studied…
Abstract Number: 1799 • 2019 ACR/ARP Annual Meeting
Wellness and Resiliency Among Recent Rheumatology Fellowship Graduates: A Qualitative Study
Priyanka Iyer¹ and Bharat Kumar ², ¹University of Iowa Hospitals and Clinics, Iowa City, IA, ²University of Iowa Hospital and Clinics, Iowa City, IA
Background/Purpose: The recent ACR workforce projections suggest that there will be a significant shortage of rheumatologists by 2030. Retirement of senior physicians, an increase in…
Abstract Number: 1800 • 2019 ACR/ARP Annual Meeting
Safety and Humoral Immunogenicity to Herpes Zoster Vaccine in Patients with Rheumatoid Arthritis (interim Analysis)
Ori Elkayam¹, Itzhak Rosner ², Devy Zisman ³, Merav Lidar ⁴, Reuven Mader ⁵, Amir Bieber ⁵, Alexandra Balbir-Gurman ⁶, Mirit Amit ⁷, Smadar Gertel ⁸ and Victoria Furer ⁹, ¹Rheumatology Department, Tel Aviv Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Israel., Tel Aviv, Israel, ²Bnei Tzion, Haifa, Israel, ³Carmel Hospital and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel, Haifa, Israel, ⁴Sheba Medical Center, Ramat Gan, Israel, ⁵Ha emek medical center, Afula, Israel, ⁶Rambam Medical Center, Haifa, Israel, ⁷Shamir medical center, Zerifin, Israel, ⁸Tel Aviv medical center, Tel Aviv, Israel, ⁹Sourasky Medical Center, Tel-Aviv, Israel
Background/Purpose: To evaluate the safety and humoral immunogenicity of a live attenuated herpes zoster (HZ) vaccine in patients with rheumatoid arthritis (RA) compared with healthy…
Abstract Number: 1801 • 2019 ACR/ARP Annual Meeting
Comparison of Infection-Related Hospitalization Risk and Cost in TNFi-Experienced Medicare Beneficiaries with Rheumatoid Arthritis Treated with Abatacept or Other Targeted Disease-Modifying Anti-Rheumatic Drugs
Vardhaman Patel¹, Zulkarnain Pulungan ², Anne Shah ², Mahesh Kambhampati ², Francis Lobo ³ and Allison Petrilla ², ¹Bristol-Myers Squibb, New York City, NY, ²Avalere, washington, DC, ³Bristol-Myers Squibb Company, Princeton, NJ
Background/Purpose: The risk and cost of infection-related hospitalizations in tumor necrosis factor inhibitors (TNFi)-experienced patients with rheumatoid arthritis (RA) receiving subsequent targeted disease-modifying antirheumatic drug…
Abstract Number: 1802 • 2019 ACR/ARP Annual Meeting
Utility of Repeat Latent Tuberculosis Testing in Patients Taking Biologics
Urmi Khanna¹, Ariana Ellis ², AbdulAziz Galadari ³, Jeffery Hu ⁴, Josh Gallop ⁵, M. Elaine Husni ⁶ and Anthony Fernandez ⁷, ¹Department of Dermatology , Cleveland Clinic, Cleveland, OH, ²Northeast Ohio Medical University, Cleveland, OH, ³Cleveland Clinic, Abu Dhabi, Cleveland, ⁴Case Western Reserve University, Cleveland, ⁵Cleveland Clinic Lerner College of Medicine, Cleveland, OH, ⁶Department of Rheumatologic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ⁷Department of Dermatology and Pathology, Cleveland Clinic, Cleveland, OH
Background/Purpose: Guidelines for repeat Latent Tuberculosis Infection (LTBI) testing while on biologics are not clearly defined. The American College of Rheumatology recommends repeat LTBI screening…
Abstract Number: 1803 • 2019 ACR/ARP Annual Meeting
Performance of the RABBIT Infection Score in a Prospective Multicenter Cohort of Rheumatoid Arthritis Patients from Argentina
Rodrigo Garcia Salinas¹, Maria Alicia Lazaro ², Santiago Scarafia ³, Alejandra Cusa ², Nieves Capozzi ⁴, Luciana Casalla ⁴, Lucia Zarate ⁴, Maria de la Vega ⁵, Maria Correa ⁶, Gustavo Casado ⁷, Silvia Papasidero ⁸, Oscar Rillo ⁹, Nevil Alejandro Muñoz ¹⁰, Mariana Benegas ¹¹, Karin Kirmayr ¹², Maria Paula Girard Bosch ¹³, Maria Victoria Martire ¹⁴ and Ramiro Gomez ¹⁵, ¹Hospital Italiano de La Plata, La plata, Buenos Aires, Argentina, ²IARI, Buenos Aires, ³Hospital Municipal "San Cayetano", Buenos Aires, Buenos Aires, Argentina, ⁴Hospital Posadas, Buenos Aires, ⁵CEIM Investigaciones Medicas, Buenos Aires, Argentina, ⁶Consultorios Reumatológicos Pampa, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ⁷Hospital Militar Central, Buenos Aires, ⁸Hospital General de Agudos Dr. E. Tornú, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ⁹Hospital Pirovano, Buenos Aires, ¹⁰Hospital Ramos Mejia, Buenos Aires, ¹¹Sanatorio Mendez, Buenos Aires, ¹²Hospital Zonal Bariloche, Bariloche, ¹³Instituto Médico Platense, La Plata, ¹⁴Hospital San Martín. Instituto Médico Platense, La Plata, ¹⁵Hospital de Clínicas José de San Martín, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
Background/Purpose: The biologics therapies in rheumatoid arthritis (RA) implies a well-known risk of infection. It is of utterly importance to count with predictive models to…
Abstract Number: 1804 • 2019 ACR/ARP Annual Meeting
Safety of the Zoster Vaccine Recombinant, Adjuvanted in Rheumatoid Arthritis and Other Systemic Rheumatic Disease Patients: A Single Center’s Experience with 400 Patients
Emma Stevens¹, Michael Weinblatt ¹, Elena Massarotti ², Frances Griffin ¹, Srinivas Emani ¹ and Sonali Desai ³, ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, ³Brigham and Women's Hospital Assistant Professor of Medicine, Harvard Medical S, Boston, MA
Background/Purpose: Patients with rheumatoid arthritis (RA) and other systemic diseases (SD) are at an increased risk of developing Herpes Zoster (HZ) due to either the…
Abstract Number: 1805 • 2019 ACR/ARP Annual Meeting
Perioperative Anti-rheumatic Medications Are Not Associated with 30-day Odds of Infection in Rheumatoid Arthritis Patients Undergoing Surgery: A Retrospective Cohort Study
Marianne Kerski¹, Peter Boersma ², Eric Miller ³, Ashley Brenner ⁴, Genevieve Melton ⁵ and Anna Shmagel ⁶, ¹University of Minnesota Medical School, Minneapolis, MN, ²University of Minnesota School of Public Health, Minneapolis, ³University of Minnesota, Woodbury, MN, ⁴University of Minnesota Best Practices Integrated Informatics Core (BPIC), Minneapolis, MN, ⁵University of Minnesota Department of Surgery, Minneapolis, MN, ⁶University of Minnesota, Minneapolis, MN
Background/Purpose: Perioperative management of anti-rheumatic drugs in rheumatoid arthritis (RA) patients undergoing surgery remains controversial. Previous studies produced conflicting results, and data on non-orthopedic surgeries…
Abstract Number: 1806 • 2019 ACR/ARP Annual Meeting
Inflammatory Arthritis Induced by Immune Checkpoint Inhibitor Therapy: A Distinct Clinical Entity and Immunologic Phenotype
Uma Thanarajasingam¹, Xingxing Zhu ¹, Xian Zhou ¹, Jane Jaquith ¹, Yanfeng Li ¹ and Hu Zeng ¹, ¹Mayo Clinic, Rochester, MN
Background/Purpose: Immune checkpoint inhibitors (ICIs) are being used in the treatment of a variety of malignancies. ICIs target cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), programmed cell-death…
Abstract Number: 1807 • 2019 ACR/ARP Annual Meeting
Teprotumumab, a Novel Biologic for Active Thyroid Eye Disease
George J. Kahaly ¹, Saba Sile ², Elizabeth H.Z. Thompson ², Thomas Vescio ³, Renee Perdok ³, Jeffrey W. Sherman³, Terry J. Smith ⁴ and Raymond S. Douglas ⁵, ¹Johannes Gutenberg University Medical Center, Mainz, Germany, ²Horizon Therapeutics plc, Brisbane, CA, ³Horizon Therapeutics plc, Lake Forest, IL, ⁴University of Michigan Kellogg Eye Center, Ann Arbor, MI, ⁵Cedars Sinai Medical Center, Los Angeles, CA
Background/Purpose: Thyroid eye disease (TED) is a debilitating autoimmune disorder characterized by inflammation and exophthalmia along with significantly altered appearance and vision changes. TED is…
Abstract Number: 1808 • 2019 ACR/ARP Annual Meeting
Immune Checkpoint Inhibitor-Induced Inflammatory Arthritis Persists After Immunotherapy Cessation
Tawnie Braaten¹, Julie Brahmer ¹, Patrick Forde ¹, Dung Le ¹, Evan Lipson ¹, Jarushka Naidoo ¹, Megan Schollenberger ¹, Lei Zheng ¹, Michelle Jones ¹, Ami Shah ², Clifton Bingham ³ and Laura Cappelli ³, ¹Johns Hopkins, Baltimore, MD, ²Johns Hopkins Hospital, Baltimore, MD, ³Johns Hopkins University, Baltimore, MD
Background/Purpose: The use of immune checkpoint inhibitor (ICI) therapy for malignancy is growing. Various autoimmune and inflammatory syndromes, known as immune-related adverse events (irAEs) have…
Abstract Number: 1809 • 2019 ACR/ARP Annual Meeting
A Quarter of Patients Treated with Checkpoint Inhibitors Develop Immune-Related Adverse Events: A University Center Experience
Celine Zhou ¹, Whitney Elg-Salsman¹, Sonam Kiwalkar ², Nishad Sathe ¹, Marcia Friedman ¹ and Atul Deodhar ², ¹Oregon Health and Science University, Portland, OR, ²Oregon Health & Science University, Portland, OR
Background/Purpose: Immune checkpoint inhibitors (ICIs) are increasingly becoming the mainstay of management of advanced malignancies, but can result in immune related adverse events (irAEs) affecting…
Abstract Number: 1810 • 2019 ACR/ARP Annual Meeting
Rheumatic Toxicities Associated with Immune Checkpoint Inhibitors: An Observational, Retrospective, Pharmacovigilance Study
Céline Anquetil¹, Olivier Benveniste ¹, Javid ‎ Moslehi ², Douglas Johnson ², Bénédicte lebrun-vignes ¹, Olivier Lambotte ³, Joe-Elie Selam ⁴, Jean-Philippe Spano ⁵ and Yves Allenbach ¹, ¹Sorbonne Université, Paris, France, ²Vanderbilt, Nashville, ³APHP Médecine Interne/Immunologie Clinique, Hôpital Bicêtre, Paris, France. Université Paris Sud 11 – INSERM U1184 - CEA, Immunology of Viral Infections and Autoimmune Diseases, IDMIT Department, IBFJ, Fontenay-aux-Roses & Le Kremlin-Bicêtre, France., Paris, France, ⁴Sorbonne université, Paris, ⁵Sorbonne Université, Paris, French Guiana
Background/Purpose: Monoclonal antibodies targeting co-inhibitory immune checkpoints (PD-1/PDL1 axis or CTLA-4) showed unprecedented clinical activity in several types of cancer by restoring antitumor immune responses.…
Abstract Number: 1811 • 2019 ACR/ARP Annual Meeting
Commonly Used Drugs in Rheumatology May Alter Anti-Tumoral Response to Immune Checkpoint Inhibitors
Marie Kostine¹, Eleonora Mauric ², Thomas Barnetche ³, Léa Rouxel ³, Caroline Dutriaux ⁴, Léa Dousset ⁴, Sorilla Prey ⁴, Marie Beylot-Barry ⁴, Julien Seneschal ⁵, Rémi Veillon ⁶, Vergnenegre Charlotte ⁶, Amaury Daste ⁷, Domblides Charlotte ⁷, Baptiste Sionneau ⁷, Marine Gross-Goupil ⁷, Alain Ravaud ⁷, Edouard Forcade ⁸, Bernard Bannwarth ³, Nadia Mehsen-Cetre ³, Marie-Elise Truchetet ⁹, Christophe Richez ¹⁰ and Thierry Schaeverbeke ³, ¹Department of Rheumatology, Bordeaux, France, ²FHU ACRONIM, Bordeaux University Hospital, Bordeaux, France, ³FHU ACRONIM, Department of Rheumatology, Centre Hospitalier Universitaire, Bordeaux, France, Bordeaux, France, ⁴FHU ACRONIM, Department of Dermatology, Centre Hospitalier Universitaire, Bordeaux, France, Bordeaux, France, ⁵department of dermatology, centre hospitalier universitaire de Bordeaux, BORDEAUX, France, ⁶Department of Pneumology, Centre Hospitalier Universitaire, Bordeaux, France, Bordeaux, France, ⁷Department of Oncology, Centre Hospitalier Universitaire, Bordeaux, France, Bordeaux, France, ⁸Department of Hematology, Centre Hospitalier Universitaire, Bordeaux, France, Bordeaux, France, ⁹FHU ACRONIM, Department of Rheumatology, Centre Hospitalier Universitaire, Bordeaux, France. Bordeaux University, CNRS 5164, 33000 Bordeaux, France, Bordeaux, France, ¹⁰Pellegrin Hospital, University Hospital of Bordeaux, Bordeaux, France
Background/Purpose: Immune checkpoint inhibitors (ICIs) are revolutionizing the treatment of some advanced cancers. Gut microbiota has emerged as an important component of anti-tumoral response and…
Abstract Number: 1812 • 2019 ACR/ARP Annual Meeting
Delineating Early Response Trajectories to Biologics in Polyarticular Course Juvenile Idiopathic Arthritis
Lily SH Lim¹, Armend Lokku ², Sarah Ringold ³ and Eleanor M. Pullenayegum ⁴, ¹University of Manitoba, Winnipeg, MB, Canada, ²University of Toronto, TOronto, ON, Canada, ³Seattle Children's, Seattle, ⁴Child Health Evaluative Sciences, The Hospital for Sick Children, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
Background/Purpose: Most biologic trials in juvenile idiopathic arthritis (JIA) treat all participants with the biologic under study for 12 to 16 weeks before randomizing responders…

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