ACR Meeting Abstracts

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  • Abstract Number: 816 • 2018 ACR/ARHP Annual Meeting

    Development of Thoracic Aortic Aneurysms in Patients with Polymyalgia Rheumatica: Underdiagnosed Giant Cell Arteritis?

    Nicolas Martin Marin Zucaro1, Marina Scolnik2, Florencia Beatriz Mollerach3, Valeria Scaglioni2, Luciano Fernando Lo Giudice1, Jose Maximiliano Martinez P4, John Fredy Jaramillo Gallego1 and Enrique R Soriano5, 1Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Capital Federal, Argentina, 2Rheumatology Unit, Internal Medicine Service. Hospital Italiano Buenos Aires. Argentina, Buenos Aires, Argentina, 3Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 4Rheumatology, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 5Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, CABA, Argentina

    Background/Purpose: Polymyalgia Rheumatica (PMR) and Giant Cell Arteritis (GCA) are close-related entities. Imaging studies have suggested that subclinical inflammation of the large arteries is frequent…
  • Abstract Number: 817 • 2018 ACR/ARHP Annual Meeting

    Current Diagnostic Delays in Vasculitis and Factors Associated with Time to Diagnosis

    Antoine G. Sreih1, Dianne Shaw2, Kalen Young3, Cristina Burroughs4, Joyce Kullman5, Kirthi Machireddy6, Carol A. McAlear1, George Casey3 and Peter A. Merkel7, 1Division of Rheumatology, University of Pennsylvania; Perelman School of Medicine, Philadelphia, PA, 2University of North Carolina, Chapel Hill, NC, 3Vasculitis Foundation, Kansas city, MO, 4University of South Florida, Tampa, FL, 5Vasculitis, Vasculitis Foundation, Kansas City, MO, 6University of Pennsylvania; Perelman School of Medicine, Philadelphia, PA, 7Division of Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

       Background/Purpose: Despite recent advancements in the evaluation and management of vasculitis, patients with vasculitis continue to encounter diagnostic delays. These delays are often associated…
  • Abstract Number: 818 • 2018 ACR/ARHP Annual Meeting

    Visual Involvement in Giant Cell Arteritis: A Prospective Multi Center Study

    Faidra Laskou1, Tin Aung2, Dawn Gayford3, Siwalik Banerjee2, Cynthia S. Crowson4, Eric L. Matteson5 and Bhaskar Dasgupta6, 1Rheumatology, Southend University Hospital NHS Foundation Trust, Southend, UK, Southend-On-Sea, United Kingdom, 2Rheumatology, Southend University Hospital NHS Foundation Trust, Southend, UK, Southend-on-Sea, United Kingdom, 3Rheumatology, Southend University Hospital NHS Foundation Trust, Southend, UK, westcliff-on-Sea, United Kingdom, 4Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, 5Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, 6Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea, United Kingdom

    Background/Purpose: Under reporting of visual impairment attributable to GCA is likely; certificates of visual impairment do not include GCA as a category. Delayed presentation, recognition…
  • Abstract Number: 819 • 2018 ACR/ARHP Annual Meeting

    Use of Takayasu Arteritis Damage Score (TADS) to Measure Damage in Takayasu Arteritis

    Sivakumar Mambakkam Rajappa1 and Krishnamurthy Venkataraman2, 1Rheumatology and Immunology, GLB Hospitals, Chennai, India, 2Rheumatology, Apollo Speciality Hospitals, Chennai, India

    Background/Purpose: Takayasu Arteritis (TA) in India frequently present with complications, indicating the need for a specific damage index to capture the accumulation of disease-related scars…
  • Abstract Number: 820 • 2018 ACR/ARHP Annual Meeting

    Incidence And Seasonal Variation Of Biopsy-Proven Giant Cell Arteritis – Revisited: A 20-Year Population-Based Study From Sweden

    Pavlos Stamatis1, Carl Turesson2, Jan-Åke Nilsson2 and Aladdin Mohammad3, 1Clinical Sciences, Rheumatology Lund, Lund University, Lund, Sweden, 2Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 3Rheumatology, Department of Clinical Sciences, Lund, Lund University, Lund, Sweden

    Background/Purpose: To investigate the incidence rate and seasonal variation of biopsy-proven giant cell arteritis (GCA) in a well-defined population in southern Sweden. Methods: The study…
  • Abstract Number: 821 • 2018 ACR/ARHP Annual Meeting

    Comparison of Aortitis Vs Non-Inflammatory Aortic Aneurysms Among Patients Who Undergo Open Aortic Aneurysm Repair

    Laarni Quimson1, Bryan Rea2 and Rennie L. Rhee3, 1Internal Medicine, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Rheumatology, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Comparison of Aortitis vs Non-Inflammatory Aortic Aneurysms Among Patients Who Undergo Open Aortic Aneurysm RepairBackground/Purpose: Distinguishing aortitis-induced aneurysms from more common non-inflammatory aortic aneurysms is…
  • Abstract Number: 822 • 2018 ACR/ARHP Annual Meeting

    Immuno-Inflammatory Markers and MR-Angiographic Imaging to Detect Disease Activity in Takayasu Arteritis

    Andrea D. Gloor1, Daniel Yerly2, Jennifer L. Cullmann3, Sabine Adler1 and Peter M. Villiger1, 1Department of Rheumatology, Immunology and Allergology, Inselspital, University Hospital of Bern, Bern, Switzerland, 2Department of Biomedical Research, University of Bern, Bern, Switzerland, 3Institute of Diagnostic, Interventional and Pediatric Radiology, Inselspital, University Hospital of Bern, Bern, Switzerland

    Background/Purpose: There is an unmet need for tools to quantify local disease activity in TAK.Methods: Sera of 21 TAK patients, aged between 18 and 56…
  • Abstract Number: 823 • 2018 ACR/ARHP Annual Meeting

    Survival of Biopsy Proven Giant Cell Arteritis in Northern Italy: Correlation with Clinical, Laboratory and Histopathological Findings

    Luigi Boiardi1, Pierluigi Macchioni2, Francesco Muratore3, Mariagrazia Catanoso2, Alberto Cavazza4, Pamela Mancuso5, Luca Cimino6, Giovanna Restuccia7 and Carlo Salvarani8, 1Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, 2Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, 3Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio Emilia, Italy, 4Pathology Unit, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, 5Interinstitutional Epidemiology Unit, Azienda USL di Reggio Emilia (Local Health Authority) and Azienda Ospedaliera IRCCS di Reggio Emilia,, Reggio Emilia, Italy, 6Ophthalmology Unit, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, 7Rheumatology Unitn, Arcispedale S Maria Nuova, IRCCS, 42100, Italy, 8Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio-Emilia, Italy

    Background/Purpose: To correlate survival with clinical, laboratory and histopathological findings in a population based cohort of patients with biopsy-proven giant cell arteritis (GCA) living in…
  • Abstract Number: 824 • 2018 ACR/ARHP Annual Meeting

    Comparing Childhood- Versus Adult-Onset Polyarteritis Nodosa

    Michele Iudici1, Pierre Quartier2, Christian Pagnoux3, Etienne Merlin4, Christian Agard5, Achille Aouba6, Pascal Roblot7, Pascal Cohen1, Benjamin Terrier1, Luc Mouthon1, Loïc Guillevin1 and Xavier Puéchal1, 1National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 2AP-HP, Institut des Maladies Génétiques (IMAGINE), and Université Paris-Descartes, Necker-Enfants Malades Hospital, Paris, France, 3Division of Rheumatology, Division of Rheumatology, Mount Sinai Hospital, Toronto, ON, Canada, 4CHU, Clermont-Ferrand, France, 5Nantes Hôtel Dieu, Nantes, France, 6Caen, Caen, France, 7CHU, Poitiers, France

    Background/Purpose: To investigate differences between childhood (cPAN)- and adult-onset polyarteritis nodosa (aPAN) patients. Methods: cPAN patients’ clinical findings at onset and outcomes were compared to…
  • Abstract Number: 825 • 2018 ACR/ARHP Annual Meeting

    Assessment of Damage and Prognosis in Patients with Adult IgA Vasculitis: Retrospective Multicentered Cohort Study

    Ummugulsum Gazel1, Ahmet Omma2, Alper Sari3, Dondu Uskudar Cansu4, Ayten Yazici5, Ayse Cefle5, Cemal Bes6, Omer Karadag7, Haner Direskeneli8 and Fatma Alibaz-Oner1, 1Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, 2Rheumatology, Ankara Numune Education and Research Hospital, Ankara, Turkey, 3Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 4Rheumatology, Osmangazi University, School of Medicine, Eskısehir, Turkey, 5Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey, 6Department of Rheumatology, Health Sciences University Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey, 7Rheumatology, Hacettepe University, Faculty of Medicine, Ankara, Turkey, 8Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: IgA Vasculitis is a leukocytoclastic vasculitis involving small vessels with depositions of immune complexes containing IgA. IgA Vasculitis is a predominantly pediatric vasculitis. There…
  • Abstract Number: 826 • 2018 ACR/ARHP Annual Meeting

    Does Anti-Glomerular Basement (anti-GBM) Antibody Positivity Correlate with Relapse in Patients with Anti-GBM Disease?

    Nicole Droz1, Alexis Katz2, John Sedor3 and Rula A Hajj-Ali1,4, 1Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, 2Cleveland Clinic Foundation, Cleveland, OH, 3Nephrology, Cleveland Clinic Foundation, Cleveland, OH, 4Rheumatic and Immunologic Disease, Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Anti-GBM disease is characterized by rapidly progressive glomerular nephritis with or without pulmonary hemorrhage.  It is usually monophasic in nature and disease severity correlates…
  • Abstract Number: 827 • 2018 ACR/ARHP Annual Meeting

    Rituximab Therapy for Systemic Rheumatoid Vasculitis: Indications, Outcomes and Adverse Events

    Caitrin Coffey1, Michael Richter1, Cynthia S. Crowson2, Matthew J. Koster3, Kenneth J. Warrington4 and Ashima Makol3, 1Internal Medicine, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN, 4Rheumatology, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN

    Background/Purpose: Rheumatoid vasculitis (RV) is a rare systemic inflammatory process affecting small to medium sized blood vessels in patients with rheumatoid arthritis (RA). RV confers…
  • Abstract Number: 828 • 2018 ACR/ARHP Annual Meeting

    Medium and Small-Sized Vessel Involvement in Hypereosinophilic Syndrome

    Julien Rohmer1, Matthieu Groh2, Maxime Samson3, Jonathan London4, Marie JACHIET5, Diane Rouzaud6, Antoinette Perlat7, Romain Paule8, Felipe SUAREZ9, Jean-Emmanuel Kahn10, Loïc Guillevin11 and Benjamin Terrier12, 1National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, Internal medicine, France, Paris, France, 2Internal Medicine, Foch, Suresnes, France, 3Dijon University Hospital, Dijon, France, 4Service de Médecine Interne, Hôpital Cochin, Centre de référence national pour les maladies systémiques autoimmunes rares d’Ile de France, DHU Authors, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France, Paris, France, 5Dermatology department, St Louis Hospital, Paris, France, 6Université Paris-Diderot, Paris, France, 7Internal medicine, CHU de Rennes, Rennes, France, 8Department of Internal Medicine, Department of Internal Medicine, Cochin University Hospital, Paris, France, 9Hematology Department, Necker Hospital, Paris, France, 10Service de Médecine Interne, Centre de Référence des Syndromes Hyperéosinophiliques-CEREO, Hôpital Foch, Université Versailles–Saint-Quentin-en-Yvelines, Suresnes, France, 11Medecine Interne, Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 12National Referral Center for Rare Systemic Autoimmune Diseases, Paris Cochin, France, Paris, France

    Background/Purpose: Primary systemic vasculitis, especially eosinophilic granulomatosis with polyangiitis and polyarteritis nodosa, can be associated with blood and tissue eosinophilia. Conversely, eosinophilia in the context…
  • Abstract Number: 829 • 2018 ACR/ARHP Annual Meeting

    DNA Damage and Repair in Patients with Cryoglobulinemic Vasculitis Treated with Direct Anti-HCV Drugs

    Mohamed Tharwat Hegazy1, Walaa Allam2, Mohamed A Hussein1, Naguib Zoheir3, Luca Quartuccio4, Patrice Cacoub5, Wahid Doss6, Mona I. Ellawindi7, Mary Fawzy1, Loïc Guillevin8, Ahmed El Ray9, Maissa El Said El Raziky10,11, Magdy El Serafy6, Sherif El Khamisy2,12 and Gaafar Ragab1, 1Internal Medicine Department, Rheumatology and Clinical Immunology Unit, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, 2Center for Genomics, Zewail City of Science and Technology, Giza, Egypt, Giza, Egypt, 3Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, 4Rheumatology Clinic, Academic Hospital S. M. della Misericordia, Medical Area Department, University of Udine, Italy, Udine, Italy, 5Internal Medicine Department, University Hospital “Pitié-Salpêtrière”, “Pierre et Marie Curie Paris VI” University, Paris, France, Paris, France, 6Tropical Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, 7Community Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, 8Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France, 9Theodor Bilharz Research Institute, Cairo, Egypt, Cairo, Egypt, 10Fatimid Cairo hospital, Cairo, Egypt, Cairo, Egypt, 11Tropical Medicine Department, Faculty of Medicine, Cairo University, Cairo, Egypt, cairo, Egypt, 12Krebs Institute, University of Sheffield, Sheffield, S10 2TN, UK, Sheffield, United Kingdom

    DNA Damage and Repair in Patients with Cryoglobulinemic Vasculitis Treated with Direct Anti-HCV Drugs Background/Purpose: Direct Acting Antiviral (DAA) agents were shown to be effective…
  • Abstract Number: 830 • 2018 ACR/ARHP Annual Meeting

    Primary Central Nervous System Vasculitis with Tumor-like Presentation

    Carlo Salvarani1, Robert D. Brown Jr.2, Teresa J. H. Christianson3, Caterina Giannini4, John Huston III5 and Gene G. Hunder6, 1Azienda USL-IRCCS di Reggio Emilia e Università di Modena e Reggio Emilia, Reggio Emilia, Italy, 2Department of Neurology, Mayo Clinic, Rochester, MN, 3Division of Biomedical Statistics & Informatics, Mayo Clinic, Rochester, MN, 4Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, 5Mayo Clinic, Rochester, MN, 6Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose: The aim of this study was to determine the frequency of ML in a large cohort of patients with PCNSV and compare the presenting…
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