Abstracts Archive - Page 1054 of 2607 - ACR Meeting Abstracts

Abstract Number: 1708 • 2019 ACR/ARP Annual Meeting
Azathioprine and Glucocorticoid Combination Might Be a Good Treatment Option to Achieve Remission in Patients with IgG4-related Disease
Aydan Köken Avşar¹, Onay Gercik ², Gercek Can ³, Berrin Zengin ⁴, Sinem Burcu Kocaer ⁵, Atilla Okan Kılıç ⁶, Sadettin Uslu ⁷, Ali Karakaş ⁵, Merih Birlik ⁵, Servet Akar ⁸ and Fatos Onen ⁹, ¹Dokuz Eylul University School of Medicine, Rheumatology,, Türkiye, Izmir, Turkey, ²Izmir Katip Celebi University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, İzmir, Turkey, ³Dokuz Eylul University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Izmir, Izmir, Turkey, ⁴Dokuz Eylul University School of Medicine, Rheumatology,, Turkey,Izmir, Izmir, Turkey, ⁵Division of Rheumatology, Dokuz Eylül University School of Medicine, İzmir, Turkey, Turkey,Izmir, Izmir, Turkey, ⁶Dokuz Eylul University School of Medicine, Internal Medıcıne, Turkey,Izmir, Izmir, Turkey, ⁷Division of Rheumatology, Dokuz Eylül University School of Medicine, İzmir, Turkey, Izmir, Turkey, ⁸Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, İzmir, Turkey, ⁹Dokuz Eylul University School of Medicine, Division of Rheumatology, İzmir, Turkey
Background/Purpose: IgG4-related disease is a recently recognised inflammatory disease of unkown etiology, often seen in men over the age of 50 and may affect many…
Abstract Number: 1709 • 2019 ACR/ARP Annual Meeting
Juvenile-Onset IgG4-Related Disease: A Systematic Review
Eduardo Martin-Nares¹, Talia Díaz-Prieto ², Enrique Faugier-Fuentes ², Luis A. Aparicio Vera ² and Gabriela Hernandez-Molina ¹, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Department of Rheumatology, Hospital Infantil de México Federico Gómez, Mexico City, Mexico
Background/Purpose: IgG4-related disease (IgG4-RD) presenting in the pediatric age is rare. Natural history and outcomes are not well defined. The aim of this study was…
Abstract Number: 1710 • 2019 ACR/ARP Annual Meeting
Chemokine and Cytokine Tear Profile of Patients with IgG4-Related Disease
Eduardo Martin-Nares¹, Luis Llorente ¹, Guadalupe Lima ¹, Diego Hernández-Ramírez ¹, Isela Chan-Campos ¹, Vanessa Saavedra-González ¹ and Gabriela Hernandez-Molina ¹, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
Background/Purpose: The lacrimal gland is frequently involved in both IgG4-related disease (IgG4-RD) and Sjögren’s syndrome (SS) and presents with swelling and/or dry eye symptoms. Although…
Abstract Number: 1711 • 2019 ACR/ARP Annual Meeting
Distinctive Imaging Features Between IgG4-Related Ophthalmic Disease and Graves’ Orbitopathy: A Comparative Study
Eduardo Martin-Nares¹, Oziel Amaya-Piña ², Rosa Delia Delgado Hernández ² and Gabriela Hernandez-Molina ¹, ¹Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Department of Radiology and Molecular Medicine, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
Background/Purpose: IgG4-related ophthalmic disease (IgG4-ROD) may present as a cause of orbital myositis leading to proptosis and diplopia. This clinical scenario can be mistakenly diagnosed…
Abstract Number: 1712 • 2019 ACR/ARP Annual Meeting
Head and Neck Involvement of IgA Vasculitis: A Case-Control Study
Michel Villatoro-Villar¹, David Wetter ¹, Cynthia Crowson ², Kenneth Warrington ¹ and Matthew Koster ¹, ¹Mayo Clinic Rochester, Rochester, MN, ²Mayo Clinic Rochester, Rochester
Background/Purpose: IgA vasculitis (IgAV) is an immune-complex mediated, small-vessel vasculitis which predominantly involves the skin on the lower extremities. Head and neck involvement is rarely…
Abstract Number: 1713 • 2019 ACR/ARP Annual Meeting
Drug-induced IgA Vasculitis: Data from the French Pharmacovigilance Network and the WHO VigiBase
CAMILLE RASMUSSEN¹, MYLENE TISSEYRE ², JULIE GARON-CZMIL ², MARINA ATZENHOFFER ³, Loïc Guillevin ⁴, LAURENT CHOUCHANA ² and Benjamin Terrier ⁴, ¹Cochin Hospital, National Referral Center for Rare Systemic Autoimmune Diseases, PARIS, PARIS, France, ²PHARMACOVIGILANCE, COCHIN HOSPITAL, PARIS, PARIS, France, ³PHARMACOVIGILANCE CENTER LYON, FRANCE, LYON, France, ⁴National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France
Background/Purpose: IgA vasculitis (IgAV) is an immune complex small-vessel vasculitis, with IgA1-dominant immune deposits. Drug-induced IgAV were rarely reported in the literature, but no systematic…
Abstract Number: 1714 • 2019 ACR/ARP Annual Meeting
Can We Predict Early Relapses in Adult IgA Vasculitis?
Jaka Ostrovrsnik¹, Ziga Rotar ¹, Matija Tomsic ¹ and Alojzija Hocevar ¹, ¹Department of Rheumatology, University Medical Center Ljubljana, Slovenia, Ljubljana, Slovenia
Background/Purpose: In adults, IgA vasculitis (IgAV) frequently takes a severe course in the acute phase of the disease. Data on long term outcomes is limited.…
Abstract Number: 1715 • 2019 ACR/ARP Annual Meeting
Predictors of Gastrointestinal and Renal Involvement in Adult IgA Vasculitis
Alojzija Hocevar¹, Ziga Rotar ² and Matija Tomšič ³, ¹Department of Rheumatology, University Medical Center Ljubljana, Slovenia, LJUBLJANA, Slovenia, ²UMC LJUBLJANA, DPT. OF RHEUMATOLOGY, LJUBLJANA, Slovenia, ³Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, LJUBLJANA, Slovenia
Background/Purpose: IgA vasculitis (IgAV) is a common vasculitis of adult population, yet the disease in adults is still poorly defined. The aim of our study…
Abstract Number: 1716 • 2019 ACR/ARP Annual Meeting
Poor-Prognosis Factors of Systemic Vasculitides with Gastrointestinal Involvement: Data from a Large Retrospective Study
Segolene Gendreau¹, Benjamin Thoreau ², François Maurier ³, Tiphaine Goulenok ¹, Laure Frumholtz ¹, Arsène Mékinian ⁴, Saskia Oro ⁵, Charlotte Bernigaud ⁵, Alexandra Audemard ¹, Maxime Samson ⁶, Antoine Gaillet ¹, Romain Sonneville ¹, Jean-Benoit Arlet ¹, Adrien Mirouse ¹, Jean-Emmanuel Kahn ⁷, Aurélie Hummel ¹, Thomas Pires ⁸, Wendy Jourde ⁸, Eric Hachulla ⁹, Pierre-Louis Carron ¹⁰, Cécile-Audrey Durel ¹¹, Francoise Sarrot-Reynauld ¹², Nathalie Tieulie ¹³, Elisabeth Diot ¹⁴, Christian Agard ¹⁵, Guillaume Armengol ¹⁶, Alice Berezne ¹⁷, Christophe Deligny ¹⁸, Fleur Cohen ¹, Stanislas Faguer ¹⁹, Guillaume Le Guenno ²⁰, Mohamed Hamidou ¹⁵, Loïc Guillevin ²¹ and Benjamin Terrier ²¹, ¹APHP, Paris, France, ²CHU Tours, Tours, France, ³Service de Médecine Interne, Hôpital Belle Isle, Metz, Metz, France, ⁴Hôpital Saint-Antoine, APHP, Paris, Paris, France, ⁵APHP, Creteil, France, ⁶Service de Médecine Interne et Immunologie Clinique, CHU Dijon Bourgogne, Hôpital François Mitterrand, Dijon ; Université Bourgogne-Franche Comté, INSERM, EFS BFC, UMR1098, F-21000 Dijon, Dijon, France, ⁷APHP, Boulogne Billancourt, France, ⁸CHU Bordeaux, Bordeaux, France, ⁹CHU Lille, Lille, France, ¹⁰Grenoble, Grenoble, France, ¹¹Department of Internal Medicine, Hôpital Edouard Herriot, Lyon, France, Lyon, France, ¹²CHU Grenoble, Grenoble, France, ¹³University Hospital of Nice, Nice, France, ¹⁴APHP, Tours, France, ¹⁵CHU Nantes, Nantes, France, ¹⁶CHU Rouen, Rouen, France, ¹⁷CH Annecy Genevois, Annecy, France, ¹⁸CHU Martinique, Fort de France, France, ¹⁹CHU Toulouse, Toulouse, France, ²⁰CHU Clermont Ferrand, Clermont Ferrand, France, ²¹National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France
Background/Purpose: Gastrointestinal (GI) involvement was described as a poor-prognosis factor of systemic necrotizing vasculitides. However, the prognostic impact of GI involvement may vary according to…
Abstract Number: 1717 • 2019 ACR/ARP Annual Meeting
Identifying Patterns of Histopathologic Presentation in CNS Vasculitis
Chan Mi Lee¹, Richard Prayson ², Marcia Leon Rabanal ³, Leonard Calabrese ³ and Rula Hajj-ali ³, ¹Cleveland Clinic Lerner College of Medicine of Case Western Reserve University/Cleveland Clinic, Cleveland, OH, ²Anatomic Pathology/Cleveland Clinic, Cleveland, OH, ³Rheumatologic and Immunologic Disease/Cleveland Clinic, Cleveland, OH
Background/Purpose: Primary central nervous system vasculitis (CNS-V) is vasculitis confined to the brain, spinal cord and meninges. It is a rare condition with unknown pathogenesis.…
Abstract Number: 1718 • 2019 ACR/ARP Annual Meeting
Geographic Disparities in Mortality Rates of Vasculitis in the United States: 1999 to 2017
Alicia Rodriguez-Pla¹, ¹University of Arizona/Banner Health Medical Center, Tucson, AZ
Background/Purpose: Earlier diagnosis and less toxic immunosuppressive therapies have improved the survival of patients with vasculitis. Current data on mortality rates of vasculitis are limited.…
Abstract Number: 1719 • 2019 ACR/ARP Annual Meeting
Clinical Phenotypes in Relapsing Polychondritis in a Prospective Cohort
Marcela Ferrada¹, Kaitlin Quinn ², Wendy Goodspeed ³, Jeffrey KIm ⁴, Clint Allen ⁴, Arlene Sirajuddin ⁵, Marcus Chen ⁵, K Bates Gribbons ⁶, Joel S. Rosenblum ⁷, Casey A. Rimland ⁸, James Katz ¹ and Peter C. Grayson ⁹, ¹NIAMS, Bethesda, MD, ²Georgetown University Hospital/National Institutes of Health, Washington, DC, ³NIAMS, Bethesda, ⁴NIDCD, Bethesda, ⁵NHLBI, Bethesda, ⁶National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁷National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, Bethesda, MD, ⁸National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, Chapel Hill, NC, ⁹National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: Relapsing polychondritis (RP) is a systemic inflammatory disease that can be fatal. The main clinical feature that typically leads to diagnosis is ear inflammation,…
Abstract Number: 1720 • 2019 ACR/ARP Annual Meeting
Pentoxifylline Gel for Oral Ulcers in Patients with Behçet’s Syndrome
Gulen Hatemi¹, Berna Yurttas ², Zekayi Kutlubay ³, Tim Cote ⁴, Semsi Burak Derkunt ⁴, Yusuf Yazici ⁵ and Hasan Yazici ⁶, ¹Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Behcet's Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ²Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University- Cerrahpasa, Behçet's Disease Research Center, Istanbul, Turkey, Istanbul, ³Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Dermatology, Istanbul University – Cerrahpasa, Behçet’s Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ⁴Silk Road Therapeutics, Washington, DC, USA, Washington, WA, ⁵New York University School of Medicine, New York, NY, USA, New York, NY, ⁶Academic Hospital, Istanbul, Turkey, Istanbul, Turkey
Background/Purpose: Oral ulcers, the hallmark lesion of Behçet’s syndrome (BS) can be disabling and impair eating, drinking and speaking. Despite recent advances in systemic medications…
Abstract Number: 1721 • 2019 ACR/ARP Annual Meeting
Adult Primary Central Nervous System Vasculitis Treatment and Course: A Long-term Follow-up Study
Carlo Salvarani¹, Robert D Brown ², Teresa JH Christianson ², John Huston III ², Caterina Giannini ² and Gene G Hunder ², ¹Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, ²Mayo Clinic, Rochester
Background/Purpose: To evaluate long-term treatment and outcomes of a large cohort of patients with primary central nervous system vasculitis (PCNSV)Methods: The study cohort consisted of…
Abstract Number: 1722 • 2019 ACR/ARP Annual Meeting
Mixed Cryoglobulin Immune Complex Proteomics: Analysis by Mass Spectroscopy
Peter Gorevic¹, Frank Eng ², Andrea Branch ³, Ahmed Elshamy ⁴, Erin Doyle ² and Thomas Schiano ², ¹Mount Sinai Hospital, New York, ²Mount Sinai Medical Center, New York, ³Mount Sinai Medical School, New York, ⁴California Northstate University, Sacramento
Background/Purpose: BACKGROUND. Mixed Cryoglobulins (MCs) are cold precipitable Rheumatoid Factors (RFs) that provide a biomarker for immune complex formation, particularly associated with chronic Hepatitis C…

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