Abstracts Archive - Page 1049 of 2425 - ACR Meeting Abstracts

Abstract Number: 666 • 2018 ACR/ARHP Annual Meeting
Inflammation on MRI of the Sacroiliac Joints Is Highly Associated with Structural Damage in Axial Spondyloarthritis Patients in Clinical Practice: Data from the ASAS and DESIR Cohorts
Alexandre Sepriano¹, Sofia Ramiro^1,2, Robert B.M. Landewé^3,4, Maxime Dougados⁵, Désirée van der Heijde⁶ and Martin Rudwaleit⁷, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Zuyderland Medical Center, Heerlen & Leiden University Medical Center, Leiden, Netherlands, ³Zuyderland Medical Center, Heerlen, Netherlands, ⁴Amsterdam Rheumatology & Immunology Center, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁵Department of Rheumatology, Paris Descartes University and Cochin Hospital, Paris, France, ⁶Leiden University Medical Centre, Leiden, Netherlands, ⁷Internal Medicine and Rheumatology, Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany
Background/Purpose: The effect of MRI-detected inflammation on the development of radiographic damage at the sacroiliac joints (SIJ) level in patients (pts) with axial SpA (axSpA)…
Abstract Number: 667 • 2018 ACR/ARHP Annual Meeting
Assessment of Radiographic Sacroiliitis on Antero-Posterior Lumbar Radiographs As Compared to Conventional Pelvic Radiographs in Patients with Axial Spondyloarthritis
Valeria Rios Rodriguez¹, Maria Llop Vilaltella¹, Mikhail Protopopov¹, Joachim Sieper², Hildrun Haibel¹, Martin Rudwaleit³ and Denis Poddubnyy⁴, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²University Clinic Benjamin Franklin, Berlin, Germany, ³Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Bielefeld, Germany, ⁴Charité Universitätsmeidzin Berlin, Berlin, Germany
Background/Purpose: EULAR guidelines consider conventional radiograph of sacroiliac joints (SIJs) as the first recommended imaging method in case of suspected axial spondyloarthritis (axSpA). However, it…
Abstract Number: 668 • 2018 ACR/ARHP Annual Meeting
Progression of Unilateral Grade 2 Sacroiliitis in a Psoriatic Arthritis Cohort
Joy Feld¹, Justine Y. Ye², Vinod Chandran², Robert D Inman³, Nigil Haroon⁴, Richard J. Cook⁵ and Dafna D Gladman⁶, ¹Toronto Psoriatic Arthritis Research Program, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ⁴Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, Toronto, ON, Canada, ⁵Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, ⁶Department of Medicine, Toronto Psoriatic Arthritis Research Program, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Axial psoriatic arthritis (axPsA) lacks a universally accepted definition. Initial studies required ≥ unilateral grade 2 sacroiliitis (Uni2SI) but recent studies have required the…
Abstract Number: 669 • 2018 ACR/ARHP Annual Meeting
High Prevalence of Axial Spondyloarthritis in Patients with Acute Anterior Uveitis and Chronic Back Pain – Preliminary Results of a Prospective Observational Study
Rianne van Bentum¹, Frank Verbraak², Sanne Wolf³, Stevie Tan³ and Irene van der Horst-Bruinsma⁴, ¹Rheumatology, VU University Medical Center, Amsterdam, the Netherlands, Amsterdam, Netherlands, ²Ophthalmology, VU University Medical Center, Amsterdam, Netherlands, ³Ophthalmology, VU University Medical Center, Amsterdam, the Netherlands, Amsterdam, Netherlands, ⁴Rheumatology, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Acute anterior uveitis (AAU) can be associated with axial spondyloarthritis (axSpA). Previous studies even described undetected axSpA in 40% of the patients with noninfectious…
Abstract Number: 670 • 2018 ACR/ARHP Annual Meeting
Low Rate of Spinal Radiographic Progression over 2 Years in Ankylosing Spondylitis Patients Treated with Secukinumab: A Historical Cohort Comparison
Jürgen Braun¹, Hildrun Haibel², Manouk de Hooge³, Robert B.M. Landewé⁴, Martin Rudwaleit⁵, Todd Fox⁶, Aimee Readie⁷, Hanno Richards⁶, Brian Porter⁸, Ruvie Martin⁷, Denis Poddubnyy⁹, Joachim Sieper¹⁰ and Désirée van der Heijde¹¹, ¹Rheumazentrum Ruhrgebiet, Herne, Germany, ²Charité Universitätmedizin Berlin, Berlin, Germany, ³Leiden University Medical Center, Leiden, Netherlands, ⁴Maastricht Univ Medical Center, Maastricht, Netherlands, ⁵Internal Medicine and Rheumatology, Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany, ⁶Novartis Pharma AG, Basel, Switzerland, ⁷Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁸Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA, East Hanover, NJ, ⁹Charité Universitätsmedizin Berlin, Berlin, Germany, ¹⁰Charité Universitätsmeidzin Berlin, Berlin, Germany, ¹¹Leiden University Medical Centre, Leiden, Netherlands
Background/Purpose: Secukinumab, a fully human monoclonal antibody that neutralizes IL-17A, improved signs and symptoms of ankylosing spondylitis (AS) in patients (pts) in the MEASURE 1…
Abstract Number: 671 • 2018 ACR/ARHP Annual Meeting
Validation of the Rexspa (Reductive X-Ray Score for Psoriatic Arthritis) in an Argentinean Cohort of Patients with Psoriatic Arthritis
Carolina Ayelen Isnardi¹, Emilce E Schneeberger², Fernando Dal Pra³, E. Scheines^1,4, Andrea Lujan Coronel Ale⁵, Marina Natalia Fornaro⁶, Osvaldo Luis Cerda⁵ and Gustavo Citera⁵, ¹Reumatology, Instituto de Rehabilitación Psicofísica, CABA, Argentina, ²Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ³Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁴Rheumatology, Hospital Manuel Rocca, Buenos Aires, Argentina, ⁵Rheumatology Section, Instituto de Rehabilitación Psicofísica, CABA, Argentina, ⁶Section of Rheumatology, Instituto de Rehabilitación Psicofísica, buenos aires, Argentina
Background/Purpose: There are many scores available to measure radiographic joint damage in patients with PsA, but most of them were developed for RA and then…
Abstract Number: 672 • 2018 ACR/ARHP Annual Meeting
Activation of NLRP3 Inflammasomes in Peripheral Blood Mononuclear Cells of Patients with Ankylosing Spondylitis
Seong-Kyu Kim¹ and Jung-Yoon Choe², ¹Rheumatology, Daegu Catholic University School of Medicine, Daegu, Korea, Republic of (South), ²Department of Internal Medicine, Catholic university of Daegu School of Medicine, Daegu, Korea, Republic of (South)
Background/Purpose: NLRP3 inflammasome is a molecular platform triggering activation of inflammatory cytokines including interleukin-1b (IL-1b). This study aimed to assess the expression of NLRP3 inflammasome…
Abstract Number: 673 • 2018 ACR/ARHP Annual Meeting
Chronic Back Pain (CBP) in First Degree Relatives (FDRs) of Patient with Ankylosing Spondylitis (AS): Comparison with the US Population, HLA-B27 Frequency and Persistence of Symptoms over Time
John D. Reveille¹, MinJae Lee², Laura A. Diekman³, Michael Ward⁴, Lianne S. Gensler⁵, Amirali Tahanan², Mohammad H. Rahbar⁶ and Michael Weisman⁷, ¹McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, ²Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, University of Texas-McGovern Medical School, Houston, TX, ³Rheumatology, McGovern Medical School at the University of Texas Health Science Center at Houston, USA, Houston, TX, ⁴National Institutes of Health, Bethesda, MD, USA, Bethesda, MD, ⁵University of California San Francisco, San Francisco, CA, ⁶Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, McGovern Medical School at the University of Texas Health Science Center at Houston, USA, Houston, TX, ⁷Harbor UCLA Medical Center, Los Angeles, CA
Background/Purpose: We examined first degree relatives (FDRs) of patients with ankylosing spondylitis (AS) patients with chronic inflammatory back pain (CIBP), non-inflammatory CBP (NICBP) and no…
Abstract Number: 674 • 2018 ACR/ARHP Annual Meeting
Defining the Therapeutic Target in Psoriatic Arthritis: MDA Versus Dapsa
Andrea Lujan Coronel Ale¹, Osvaldo Luis Cerda¹, Marina Natalia Fornaro², Carolina Ayelen Isnardi³, Emilce E Schneeberger⁴ and Gustavo Citera¹, ¹Rheumatology Section, Instituto de Rehabilitación Psicofísica, CABA, Argentina, ²Section of Rheumatology, Instituto de Rehabilitación Psicofísica, buenos aires, Argentina, ³Reumatology, Instituto de Rehabilitación Psicofísica, CABA, Argentina, ⁴Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina
Background/Purpose: T2T guidelines for psoriatic arthritis (PsA) propose using DAPSA or MDA to define the therapeutic target, but with differences in preference among experts. Objective:…
Abstract Number: 675 • 2018 ACR/ARHP Annual Meeting
Quantitative Ultrasound of the Calcaneus Has a Role to Play in Detecting Low Bone Mineral Density in Axial Spondyloarthropathy Patients
Gillian Fitzgerald^1,2, Tochukwu Anachebe³, Ronan Mullan⁴, David Kane⁵, Kevin McCarroll⁶ and Finbar O' Shea², ¹School of Medicine, Trinity College Dublin, Dublin 2, Ireland, ²Rheumatology, St. James's Hospital, Dublin 8, Ireland, ³Department of Rheumatology, St. James's Hospital, Dublin 8, Ireland, ⁴Department of Rheumatology,, Tallaght Hospital, Dublin, Ireland, ⁵Department of Rheumatology, Tallaght Hospital, Dublin 24, Ireland, ⁶Department of Medicine for the Elderly, St. James's Hospital, Dublin 8, Ireland
Background/Purpose: Axial spondyloarthropathy (axSpA) patients have an increased risk of developing osteoporosis compared to matched controls. Dual energy x-ray absorptiometry (DXA) is the technique of…
Abstract Number: 676 • 2018 ACR/ARHP Annual Meeting
A Novel Role for the Psoriatic Arthritis Impact of Disease Questionnaire
Kishor Johnson¹, Justine Y. Ye², Vinod Chandran² and Dafna D Gladman², ¹Western University, London, ON, Canada, ²Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Psoriatic arthritis (PsA) is an inflammatory arthritis that occurs in about 30% of patients with Psoriasis (Ps). Recently, a new Patient Reported Outcome Measure…
Abstract Number: 677 • 2018 ACR/ARHP Annual Meeting
Structural Damage Characteristics of Patients with Ankylosing Spondylitis in China
Weiping Kong¹, Caroline Jefferies², Thomas Learch³, Jinrui Cui⁴, Xiaowei Gan¹, Nan Zhang¹, Yingze Zhang¹, Jianming Wang¹, Qingwen Tao¹, Xiaoping Yan¹, Michael Weisman⁵ and Mariko Ishimori⁶, ¹China-Japan Friendship Hospital, Beijing, China, ²Division of Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ³Radiology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁴Cedars-Sinai Medical Center, Los Angeles, CA, ⁵Harbor UCLA Medical Center, Los Angeles, CA, ⁶Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA
Background/Purpose: Structural damage is a major cause of poor outcomes in patients with ankylosing spondylitis (AS). In China, structural damage characteristics of AS are rarely…
Abstract Number: 678 • 2018 ACR/ARHP Annual Meeting
Ultrasonographic Evaluation of Achilles Tendon in Early Axial Spondyloarthropathy: Is There Any Difference between Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthropathy?
Shahla Vahidfar¹, Ismihan Sunar², Sebnem Ataman³, Gürkan Yılmaz⁴, Javid M. AZARABADI⁵ and Ayşe Bölükbaşı¹, ¹Physical Medicine and Rehabilitation, Ankara University Faculty of Medicine, Ankara, Turkey, ²Department of Physical Medicine and Rehabilitation, Division of Rheumatology,, Ankara University, Faculty of Medicine, Ankara, Turkey, ³Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Ankara University Faculty of Medicine, Ankara, Turkey, ⁴Physical Medicine and Rehabilitation, Rheumatology Division, Ankara University Faculty of Medicine, Ankara, Turkey, ⁵ORTHOPEDICS AND TRAUMATOLOGY, Başkent University Faculty of Medicine, Ankara, Turkey
Background/Purpose: Along with emergence of the term of ‘non-radiographic axial SpA’ (nr-AxSpA), studies comparing AS and nr-AxSpA in terms of genetic, epidemiologic, and clinical issues…
Abstract Number: 679 • 2018 ACR/ARHP Annual Meeting
Ultrasonographic Research of the Relationship between Nail Disorders and Peripheral Arthritis or Enthesitis in Patients with Psoriasis and Psoriatic Arthritis
Tadashi Okano¹, Kentaro Inui², Koji Mandai³, Yutaro Yamada⁴, Tatsuya Koike⁵ and Hiroaki Nakamura², ¹Orthopedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ²Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ³Orthopaedic surgery, Osaka City University Graduate School of Medicine, Osaka, Japan, ⁴Orthopedic surgery, Yodogawa Christian Hospital, Osaka, Japan, ⁵Center for Senile Degenerative Disorders, Osaka City University Graduate School of Medicine, Osaka, Japan
Background/Purpose: Although skin lesion is the most typical findings in patients with psoriasis (PsO), nail psoriasis is also one of the important clinical manifestation. Moreover,…
Abstract Number: 680 • 2018 ACR/ARHP Annual Meeting
Unmet Needs in the Treatment of Ankylosing Spondylitis. a Long-Term Observational Study from a Single University Center
Eleftherios Pelechas¹, Evripidis Kaltsonoudis², Paraskevi V. Voulgari³ and Alexandros Drosos⁴, ¹Rheumatology Clinic, Department οf Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece, Fellow in Rheumatology, Ioannina, Greece, ²Rheumatology Clinic, Department of Internal Medicine, Rheumatologist, Ioannina, Greece, ³Rheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, 45110, Professor of Rheumatology, Ioannina, Greece, ⁴Rheumatology Clinic, Department of Internal Medicine, Medical School University of Ioannina, Ioannina, Greece, Professor of Medicine/Rheumatology, Ioannina, Greece
Background/Purpose: Despite the progress in the treatment of ankylosing spondylitis (AS), a significant number of patients does not achieve low disease activity (LDA). The aim…

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