ACR Meeting Abstracts

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  • Abstract Number: 1084 • ACR Convergence 2025

    Access to rheumatology care in patients with new diagnosis of polymyalgia rheumatica: analysis from a national inception cohort

    Sebastian E Sattui1, Orysya Soroka2, Manuel Carpio Tumba3, Emily Holladay4, Fenglong Xie5, Sarah Mackie6, Jeffrey Curtis7, Robyn Domsic3 and Iris Navarro-Millan8, 1Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 2Weill Cornell Medicine, New York, 3University of Pittsburgh, Pittsburgh, PA, 4University of Alabama at Birmingham, Edmond, OK, 5The University of Alabama at Birmingham, Birmingham, AL, 6University of Leeds, Leeds, United Kingdom, 7University of Alabama at Birmingham, Birmingham, AL, 8Weill Cornell Medicine, Hospital for Special Surgery, Poughkeepsie, NY

    Background/Purpose: Patients with polymyalgia rheumatica (PMR) are commonly diagnosed and cared for by non-rheumatology providers (i.e., primary care). Lack of access to specialty care can…
  • Abstract Number: 1121 • ACR Convergence 2025

    Latent Class Analysis Identifies Distinct Phenotypes of Multisystem Immune-Related Adverse Events Predictive of Survival After Immune Checkpoint Inhibitors

    Tao Ming Sim1, May Shuen Tang1, Qai Ven Yap2, Alvin Wong1, Yiqing Huang1 and Frank Sen Hee Tay1, 1National University Hospital, Singapore, Singapore, 2National University of Singapore, Singapore

    Background/Purpose: Use of immune checkpoint inhibitors (ICIs) can lead to a broad spectrum of immune-related adverse events (irAEs) affecting multiple organ systems. No clear pattern…
  • Abstract Number: 1005 • ACR Convergence 2025

    CD49a Contributes to Binding and Survival of Synovial Resident Memory T cells

    Yusuke Miyashita1, Yang Yang2, Madison Mangin3, Maryrose Hahn2 and Margaret Chang2, 1Boston Children's Hospital, Brookline, MA, 2Boston Children's Hospital, Boston, MA, 3Boston Children's Hospital, St Simons Island, GA

    Background/Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune disease featured with recurrent inflammation in the same joints, a characteristic termed joint-specific memory. We previously demonstrated…
  • Abstract Number: 1079 • ACR Convergence 2025

    Sociodemographic, Clinical, and Community-Level Deprivation Factors are Associated with Health-Related Quality of Life in Systemic Sclerosis

    Sarah Smith1, Paula Ramos2, Dulaney Wilson3, Diane Kamen4 and Richard Silver1, 1Medical University of South Carolina, Charleston, SC, 2Emory University School of Medicine, Atlanta, GA, 3Medical University of South Carolina, Charleston, 4Medical University of South Carolina, Johns Island, SC

    Background/Purpose: Systemic sclerosis (SSc) is a multisystem autoimmune disease with heterogeneous manifestations and significant impairment in health-related quality of life (HRQoL). SSc outcomes are shaped…
  • Abstract Number: 1106 • ACR Convergence 2025

    Faster Ellipsoid Zone Loss in Hydroxychloroquine Retinopathy with Tapering versus Discontinuation: A Longitudinal Optical Coherence Tomography Study from a Single Center in Taiwan

    Ko-Jen Li1, Ting-Wei Chang2, Tso-Ting Lai3, Jui-Hung Kao4, TING-YUAN LAN5, Tai-Ju Lee6, pei-Hsinq lai7, Shao-Yu Pai8, Chiehyu Shen9 and Song-Chou Hsieh10, 1National Taiwan University Hospital, Taipei, Taiwan, 2National Taiwan University Hospital Hsinchu Branch, Taichung, Taiwan, 3Naitional Taiwan University Hospital, Taipei, Taiwan (Republic of China), 4Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan, Taipei, Taiwan (Republic of China), 5National Taiwan University Hospital Hsinchu Branch, Hsinchu City, Taiwan, 6National Taiwan University Hospital Hsinchu Branch, Hsinchu City, Taiwan (Republic of China), 7Taipei City Hospital, Taichung, Taiwan, 8National Taiwan University Hospital, Taichung City, Taiwan (Republic of China), 9National Taiwan University Hospital, Taipei city, Taiwan, 10National Taiwan Unuversity Hospital, Taipei City, Taiwan (Republic of China)

    Background/Purpose: Hydroxychloroquine (HCQ) retinopathy is a progressive, vision-threatening retinal disease. While HCQ is typically discontinued after toxicity is detected, some patients undergo tapering due to…
  • Abstract Number: 1105 • ACR Convergence 2025

    Association between pre-existing rheumatoid arthritis and immune-related adverse events in patients with cancer receiving immune checkpoint inhibitors

    Kevin Sheng-Kai Ma1, You Wu2, Rachael Stovall2, Jean Liew3 and Namrata Singh4, 1Center for Global Health, Perelman School of Medicine, Philadelphia, PA, 2University of Washington, Seattle, WA, 3Boston University, Boston, MA, 4University of Washington, Bellevue, WA

    Background/Purpose: Immune checkpoint inhibitors (ICIs), widely used to treat a variety of cancers, are associated with immune-related adverse events (irAEs) that are increasingly encountered in…
  • Abstract Number: 1130 • ACR Convergence 2025

    Novel Anti-Obesity Medications and Serum Urate Change Among Patients with Gout and Baseline Hyperuricemia

    Kiara Tan1, Jiaqi Wang1, Saiajay Chigurupati2, Gregory Challener3, Natalie McCormick1, Sharan Rai4, Florence Porterfield5, Chika Anekwe1, Dong Wook Kim6, Fatima Stanford7, Caroline Apovian8, Hyon K. Choi9 and Chio Yokose10, 1Massachusetts General Hospital, Boston, 2Massachusetts General Hospital, Boston, MA, 3Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, 4Massachusetts General Hospital/Harvard Medical School, Boston, MA, 5Division of Endocrinology, Massachusetts General Hospital, Boston, 6Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital, Boston, 7Neuroendocrine Unit, Pediatric Endocrinology, Massachusetts General Hospital, Boston, 8Brigham and Women's Hospital, Boston, 9MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, 10Massachusetts General Hospital, Waltham, MA

    Background/Purpose: Obesity affects >50% of individuals with gout and is the most important modifiable risk factor for gout. Thus, novel anti-obesity medications (AOM, e.g., semaglutide…
  • Abstract Number: 1052 • ACR Convergence 2025

    “Prednisone… A Necessary Evil…” Developing an Evidence-Based Benefits vs. Harms Shared Decision-Making Tool (PRED-SAFE) to Support Decisions Around Chronic Prednisone Use

    Isabella Hartel1, Jay Patel1, Justin Levinson1, Sancia Ferguson2, Carmen Campbell1, Amannda Weber3, Shelby Gomez4, David Gazeley5, Ali Duarte-Garcia6, Jennifer Barton7 and Shivani Garg8, 1University of Wisconsin, School of Medicine and Public Health, Madison, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Madison, Madison, WI, 3University of Wisconsin (UW), UW Health, Madison, WI, 4University of Wisconsin, School of Pharmacy, Madison, WI, 5Medical College of Wisconsin, Milwaukee, WI, 6Mayo Clinic, Rochester, MN, 7VA Portland Health Care System/OHSU, Portland, OR, 8University of Madison, School of Medicine and Public Health, Madison, WI

    Background/Purpose: Guidelines recommend limiting chronic prednisone use ( >5 mg/d for >3-6 mos.) given higher risks of fractures, infections, and damage. Yet, patients struggle to…
  • Abstract Number: 1071 • ACR Convergence 2025

    Depression and Mental Health Service Gaps in Autoimmune Disease: Insights from a Simulated BRFSS Dataset

    Malay Rathod1, Shivani Modi2, Veera Durga Vaishnavi Kurra3, Karan Yagnik4 and Doantrnag Du4, 1Monmouth Medical Center, Ewing, NJ, 2Jefferson Einstein Montgomery Hospital, Ewign, NJ, 3University of Oklahoma Health Sciences Center, Oklahoma City, OK, 4Monmouth Medical Center, Long Branch, NJ

    Background/Purpose: Autoimmune diseases are complex conditions that may predispose individuals to an increased mental health burden, including depression. The immune system leads to inflammation in…
  • Abstract Number: 1081 • ACR Convergence 2025

    Insurance, Gender, and COVID-19’s Effects on Health Inequity in Rheumatoid Arthritis: A 12-Year Long Population Assessment

    Ramsha Riaz1, Lifang Zhang2, Andrea Berger2, Hema Srinivasan2, Lisa Schroeder3 and Jonida Cote4, 1Geisinger Medical Center, Danville, PA, 2Geisinger Health System, Danville, PA, 3Geisinger, Danville, PA, 4Geisinger Health System, Wilkes-Barre, PA

    Background/Purpose: Recognizing health care disparities in Rheumatoid Arthritis is crucial to improving outcomes. This study analyzes factors contributing to RA care inequities.Methods: We examined RA…
  • Abstract Number: 1100 • ACR Convergence 2025

    Associations Between Pre-Existing Autoimmunity and CAR T Cell Therapy Toxicity for Cancer Treatment: A Nationwide Retrospective Cohort Study

    Gregory Challener1, Chen Wang2, David Gritsch2, Ilana Usiskin3, Zandra E. Walton1, Minna Kohler4, Hyon K. Choi5 and Jeffrey Sparks6, 1Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, 2Harvard T.H. Chan School of Public Health, Boston, 3Division of Rheumatology, Inflammation, and Immunity, Department of Medicine, Brigham and Women's Hospital, Boston, 4Massachusetts General Hospital, Harvard Medical School, Boston, MA, 5MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, 6Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Chimeric antigen receptor (CAR) T cell therapy is being investigated to treat individuals with autoimmune diseases. Data regarding the safety of CAR T cell…
  • Abstract Number: 1114 • ACR Convergence 2025

    Multi-omics Integration Analysis of the Cross-scale Mechanism of MTX-induced T2DM Risk and the Precise Intervention Strategy of Leonurine

    Mei-Feng Shi1, Fang-Shu Zou1, Xiao-Na Ma1, Wei Feng1, Yi-Fang Zhang2, Chang-Song Lin1, Min-Ying Liu2 and Qiang Xu1, 1Guangzhou University of Traditional Chinese Medicine, Guangzhou, China (People's Republic), 2The First Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China (People's Republic)

    Background/Purpose: Methotrexate (MTX) is a first-line treatment for autoimmune diseases, including rheumatoid arthritis (RA). Its potential risk of inducing type 2 diabetes mellitus (T2DM) remains…
  • Abstract Number: 1136 • ACR Convergence 2025

    The Impact of Iron Overload and HFE Genetic Mutations on Joint Disease in Haemochromatosis: Data from the Haemochromatosis Arthropathy Inception Cohorts

    Bayram Farisogullari1, Pedro Machado2, Stephanie Finzel3, Graeme Carroll4, Geraldine mcCarthy5, John Stack6, Simone Parisi7, Graca Porto8, richette pascal9, Gyorgy Nagy10, Marton Weidl10, Ann Rosenthal11, Pascal Guggenbuhl12, Katarzyna Banaszkiewicz13, Barbara Butzeck14, Howard Don15, Svenja Engelhardt16, Jeremy Shearman17, David Mitchell18, Jane Barker19, Valerie Brueton19, Philip Coathup19, Jacquie Dowsett19, Marie Duncan19, Tracey Dunleavy19, Ian Fish19, Allin Hoggarth19, Mark McKinnon19, James Minter19, Tim Osborne19, Marguerite Smith19, Christine Wright19 and Patrick Kiely20, 1University College London, London, 2Department of Rheumatology, University College London, and Department of Rheumatology, Northwick Park Hospital, London North West University Healthcare NHS Trust, Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, 3Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, 4Fiona Stanley Hospital, Perth, Western Australia, Australia, 5Mater Misericordiae University Hospital, Dublin, Ireland, 6Mater Misericordiae University Hospital, Dublin, Dublin, Ireland, 7Ospedaliera Universitaria Città della Salute e della Scienza di Torino, Turin, Italy, 8Centro Hospitalar Universitário de Santo António, Unidade Local de Saúde de Santo António, Porto, Portugal, 9Rheumatology Department, Lariboisiere Hospital, Paris, Ile-de-France, France, 10Buda Hospital of the Hospitaller Order of Saint John of God, Budapest, Hungary, 11Department of Medicine, Division of Rheumatology, Medical College of Wisconsin, Wisconsin, 12Rennes University Hospital, Rennes, France, 13University Clinical Center in Gdańsk, Smoluchowskiego 17 Street, 80-952 Gdańsk, Poland., Gdańsk, Poland, 14European Federation of Associations of Patients with Haemochromatosis,, Croissy-sur-Seine, France, 15Haemochromatosis International, Barnstaple, United Kingdom, 16University of Freiburg, Freiburg im Breisgau, Germany, 17South Warwickshire University Foundation Trust and Warwick Medical School,, Warwick, United Kingdom, 18Clongriffin Medical Centre, Dublin, Ireland, 19c/o St George's University Hospitals NHS Trust, London, United Kingdom, 20St George's University Hospitals NHS Foundation Trust, London, United Kingdom

    Background/Purpose: A EULAR task force developed classification criteria (CC) for Haemochromatosis Arthropathy (HA) using a cohort of people with the C282Y homozygous mutation and arthropathy…
  • Abstract Number: 1067 • ACR Convergence 2025

    Investigating Barriers to Care through Childhood Opportunity, Social Vulnerability, Area Deprivation, and Distance to Care in Pediatric Localized Scleroderma

    Karen Lin1, Yuhan Ma1, Simrat Morris2 and Kristina Ciaglia3, 1Scottish Rite for Children, Dallas, TX, 2UT Southwestern Medical Center and Scottish Rite for Children, Dallas, TX, 3UT Southwestern, Children's Medical Center, and Scottish Rite for Children, Dallas, TX

    Background/Purpose: Delays in diagnosis and treatment of pediatric localized scleroderma (LS) are common due to the under-recognition at initial presentation. While previous studies on pediatric…
  • Abstract Number: 1015 • ACR Convergence 2025

    Refining Administrative Algorithms For Accurate Identification of Patients with Systemic Sclerosis In Trinetx Research Network

    Gulsen Ozen1, Michael O'Rorke2, Paul Romitti2 and Robyn Domsic3, 1University of Iowa, Carver College of Medicine, Division of Immunology, Coralville, IA, 2University of Iowa College of Public Health, Department of Epidemiology, Iowa City, IA, 3University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Large data-driven medical research is invaluable in answering questions about epidemiology, genetics, therapeutics, and outcomes of rare diseases. Systemic sclerosis (SSc) is rare yet…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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