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  • Abstract Number: 1468 • 2019 ACR/ARP Annual Meeting

    Effects of Resistive Exercise on Fatigue and Disease Activity in Women with Primary Sjogren’s Syndrome

    Luciana Paula Dardin 1, Fernanda Gazoni 1, Ana Beatriz Garcia 1, Paulo Alexandre Minali 2 and Virginia Fernandes Moça Trevisani3, 1Sao Paulo Federal University - Brazil, Sao Paulo, Sao Paulo, Brazil, 2Sao Paulo Federal University - Brazil, Sao Paulo, Brazil, 3Department of Evidence-Based Medicine, Brazilian Cochrane Centre, Federal University of São Paulo, Sao Paulo, Brazil, Sao Paulo, Brazil

    Background/Purpose: Fatigue is a frequent symptom of pSS, considered debilitating and the most important cause of dysfunction in these patients. The present study aimed to…
  • Abstract Number: 1469 • 2019 ACR/ARP Annual Meeting

    New 2019 SLE EULAR/ACR Classification Criteria for SLE Are Valuable for Distinguishing Patients with SLE from Patients with pSS in Daily Practice

    Florence Assan1, Raphaele Seror 2, Gaetane Nocturne 3 and Xavier Mariette 4, 1Université Paris Sud, Hôpitaux Universitaires Paris-Sud, AP-HP, INSERM UMR 1184, Le Kremlin-Bicêtre, France, 2Hopitaux universitaires Paris Sud, Kremlin-Bicetre, France, 3Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France., Paris, France, 4Center for Immunology of Viral Infections and Autoimmune Diseases, Assistance Publique – Hôpitaux de Paris, Hôpitaux Universitaires Paris-Sud, Le Kremlin-Bicêtre, Université Paris Sud, INSERM, Paris, France

    Background/Purpose: The new 2019 SLE EULAR/ACR Classification Criteria for Systemic lupus erythematosus (SLE) have been developed to find a better equilibrium between specificity and sensitivity…
  • Abstract Number: 1470 • 2019 ACR/ARP Annual Meeting

    Health-Related Quality of Life in Primary Sjogren’s Syndrome: Insights from Using PROMIS and Comparison to ESSPRI

    Dana DiRenzo1, Susan Robinson 2, Clifton Bingham 1 and Thomas Grader-Beck 2, 1Johns Hopkins University, Baltimore, MD, 2Johns Hopkins University, Baltimore

    Background/Purpose: Background. Sjogren’s Syndrome (SS) is a chronic, autoimmune disease affecting the exocrine glands that may negatively affect health-related quality of life (HRQL). The importance…
  • Abstract Number: 1471 • 2019 ACR/ARP Annual Meeting

    Polyautoimmunity and Major Organ Involvement Prevalence in Sjögren´s Syndrome: Thyroid, Liver, Lung and Kidney as Targets. a Single Center Cross Sectional Study

    Larissa Valor1, Hannah Schenker 2, Johannes Knitza 3, Melanie Hagen 3, Jürgen Rech 4 and Georg Schett 5, 1Friedrich-Alexander-University Erlangen-Nürnberg. Department of Internal Medicine 3 - Rheumatology and Immunology. Erlangen., Erlangen, Germany, 2Friedrich-Alexander-University Erlangen-Nürnberg. Department of Internal Medicine 3 - Rheumatology and Immunology. Erlangen. Germany., Erlangen, Germany, 3Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, Erlangen, Germany, 4Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany, 5Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany

    Background/Purpose: Polyautoimmunity has been described to be associated with primary Sjögren´s syndrome (SjS) and the most frequent observed associated autoimmune diseases (AID) are autoimmune thyroid…
  • Abstract Number: 1472 • 2019 ACR/ARP Annual Meeting

    Primary Sjögren’s Syndrome and Development of Another Connective Tissue Disease During Follow-up

    MARIA FLORENCIA Rodriguez1, Anastasia Secco 2, Catalan Pellet 3, natalia herscovich 1, cristina Amitrano 4, Cecilia Asnal 5, Alejandro Nitsche 6, Julia Demarchi 7, damian duartes 8, Francisco Caeiro 9, Veronica Saurit 10, Nadia Riscanevo 11, Silvia Papasidero 12, Carla Gobbi 13, laura raiti 14, vanesa cruzat 14, Lida santiago 15, Sofia Velez 16, Gabriela Salvatierra 17 and Vicente Juarez 18, 1hospital rivadavia, buenos aires, Argentina, 2Hospital Rivadavia, Caba, Buenos Aires, Argentina, 3Rivadavia, CABA, Argentina, 4Hospital Aleman, CABA, Argentina, 5Instituto Centenario, Buenos Aires, Buenos Aires, Argentina, 6Hospital Aleman, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, 7Hospital Británico, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, 8hospital britanico, buenos aires, Argentina, 9Hospital Privado de Córdoba, Cordoba, Argentina, 10Hospital Privado, Centro Médico de Córdoba, Córdoba, Argentina, Cordoba, Argentina, 11Hospital Privado de Córdoba, Cordoba, Cordoba, Argentina, 12Hospital General de Agudos Dr. E. Tornú, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, 13CÁTEDRA DE CLÍNICA MÉDICA I, HOSPITAL CÓRDOBA, FACULTAD DE CIENCIAS MÉDICAS, UNIVERSIDAD NACIONAL DE CÓRDOBA, ARGENTINA, Cordoba, Cordoba, Argentina, 14clinica bessone, buenos aires, Argentina, 15OMI, Ciudad Autonoma de Buenos Aires, Argentina, 16Consultorio Privado S.V, Buenos Aires, Buenos Aires, Argentina, 17IPRI, Santiago del estero, Santiago del Estero, Argentina, 18Hospital Milagros de Salta, Salta, Salta, Argentina

    Background/Purpose: Primary Sjögren's Syndrome (pSS) is a chronic autoimmune disease characterized by lymphocytic infiltration of the exocrine glands. Is the connective tissue disease that is…
  • Abstract Number: 1473 • 2019 ACR/ARP Annual Meeting

    Syndecan-1 Is a Potential Biomarker for Salivary Glandular Function and Disease Activity in Patients with Sjögren’s Syndrome

    Gunwoo Kim1, Min-Su Han 2, Ju Hye Jeong 3, Man-Hoon Han 4, Sang Jin Lee 5 and Eon Jeong Nam 6, 1Division of Rheumatology, Department of Internal medicine, Daegu Fatima Hospital, Daegu, Taegu-jikhalsi, Republic of Korea, 2Laboratory for arthritis and bone biology, Fatima Research Institute, Daegu Fatima Hospital, Daegu, Taegu-jikhalsi, Republic of Korea, 3Department of Nuclear medicine, Kyungpook National University Chilgok Hospital, 807, Hoguk-ro, Buk-gu, Daegu 41404, Taegu-jikhalsi, Republic of Korea, 4Department of Pathology, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-gu, Daegu 41944, Taegu-jikhalsi, Republic of Korea, 5Division of Rheumatology, Kyungpook National University Hospital, Daegu, Republic of Korea, 6Division of Rheumatology, Department of Internal Medicine, Kyungpook National University Chilgok Hospitalospital, 807, Hoguk-ro, Buk-gu, Daegu 41404, Taegu-jikhalsi, Republic of Korea

    Background/Purpose: Sjögren’s syndrome (SS) is known as autoimmune epithelitis, because epithelial cells in the glands are the primary target of disease and play a major…
  • Abstract Number: 1474 • 2019 ACR/ARP Annual Meeting

    Factors Influencing the ESSPRI Index in Primary Sjögren’s Syndrome

    Maria Graciela Sandoval-Flores1, Isela Chan-Campos 2 and Gabriela Hernandez-Molina 2, 1Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, Distrito Federal, Mexico, 2Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: The ESSPRI is a validated index for measuring symptoms (pain, fatigue and dryness) in primary Sjögren’s syndrome (pSS). Herein we evaluated its association with…
  • Abstract Number: 1475 • 2019 ACR/ARP Annual Meeting

    Comparison of Different Remission Indices in Patients with Psoriatic Arthritis: A Post Hoc Analysis of Data from Phase 3 Tofacitinib Studies

    Gustavo Citera1, Emilce Schneeberger 2, Peter Nash 3, Josef Smolen 4, Philip Mease 5, Enrique Soriano 6, Vesna Matulic 7, Claudia Helling 8, Annette Szumski 9, Rajiv Mundayat 10, Daniela Graham 11 and Dario Ponce de Leon 12, 1Instituto de Rehabilitación Psicofísica, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, 2Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 3University of Queensland, Brisbane, Queensland, Australia, 4Medical University of Vienna, Vienna, Austria, 5Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA, 6Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina., Buenos Aires, Buenos Aires, Argentina, 7Pfizer Chile S.A., Santiago, Chile, 8Pfizer Inc, Buenos Aires, Argentina, 9Syneos Health, Princeton, NJ, 10Pfizer Inc, New York, NY, 11Pfizer Inc, Groton, CT, 12Pfizer Inc, Lima, Peru

    Background/Purpose: An international task force has agreed that remission or low disease activity (LDA) are key treatment targets for patients (pts) with PsA, and recommends…
  • Abstract Number: 1476 • 2019 ACR/ARP Annual Meeting

    Impact of Alternate Mechanism of Action Biologics and Tofacitinib on TNF-α Inhibitor Prescribing in Psoriatic Arthritis: Results from Annual National Patient Chart Audits

    Lynn Price1, Phil Pouliot 1 and Lauren Schmitt 1, 1Spherix Global Insights, Exton, PA

    Background/Purpose: TNF-α inhibitor therapy has long been the standard of care for adult patients diagnosed with moderate to severe psoriatic arthritis (PsA), though several new…
  • Abstract Number: 1477 • 2019 ACR/ARP Annual Meeting

    Golimumab Improves Direct Costs of Healthcare Utilization and Indirect Costs Within Patients with RA, PsA, and as – Analysis of a Non-Interventional Study in Germany

    Klaus Krüger 1, Gerd Burmester 2, Siegfried Wassenberg 3, Astrid Thiele 4 and Matthias Thomas5, 1Medical Centre of Rheumatology, Munich, Germany, 2Charité—University Medicine Berlin, Berlin, Germany, 3Centre of Rheumatology, Ratingen, Germany, 4Krankenhaus St. Josef Wuppertal, Wuppertal, Germany, 5MSD Sharp & Dohme GmbH, Haar, Germany

    Background/Purpose: Rheumatic diseases are associated with pain, loss of functionality, fatigue, hospitalization, sick leave, and work disability. This results in high economic burden for patients…
  • Abstract Number: 1478 • 2019 ACR/ARP Annual Meeting

    Systematic Literature Review and Network Meta-Analysis Comparing Incidence of Uveitis and IBD in Axial Spondyloarthritis Patients Treated with Anti-TNF versus Anti-IL17A in Placebo Controlled Randomized Trials

    Damien Roche1, Martin Badard 1, Laurent Boyer 2, Pierre Lafforgue 1 and Thao Pham 1, 1Aix-Marseille University, CHU Marseille, department of Rheumatology, 13,000 Marseille, France, Marseille, France, 2Aix-Marseille University, EA 3279 Research Unit, 13,000 Marseille, France, Marseille, France

    Background/Purpose: Inflammatory bowel diseases (IBD) and anterior uveitis (AU) are frequent extra-articular features of axial spondyloarthritis (axSpA). Although effect of anti-TNF on IBD and AU…
  • Abstract Number: 1479 • 2019 ACR/ARP Annual Meeting

    Multi-Symptom Impact on the EQ5D Index in Bio-naïve Active Psoriatic Arthritis Patients: An Analysis Through Week 24 of the GO-VIBRANT Study

    Alexis Ogdie1, Nan Li 2, Steve Peterson 2, Chetan Karyekar 2, Soumya Chakravarty 3, Shelly Kafka 4 and Jessica Walsh 5, 1Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2Janssen Global Services, LLC, Horsham, PA, 3Janssen Scientific Affairs, LLC; Drexel University College of Medicine, Horsham; Philadelphia, PA, 4Janssen Scientific Affairs, LLC, Horsham, PA, 5Division of Rheumatology, University of Utah, Salt Lake City, UT

    Background/Purpose: Psoriatic arthritis (PsA) is a chronic inflammatory disease characterized by peripheral arthritis, axial inflammation, dactylitis, enthesitis and skin and nail psoriasis.  The impact of…
  • Abstract Number: 1480 • 2019 ACR/ARP Annual Meeting

    Clinical Characteristics and Treatment Profiles of Patients with Ankylosing Spondylitis Who Initiated Secukinumab and Other Biologics: Results from the Corrona Psoriatic Arthritis/Spondyloarthritis (PsA/SpA) Registry

    Alexis Ogdie1, Mei Liu 2, Sabrina Rebello 2, Meghan Glynn 3, Blessing Dube 2, Robert McLean 3, Esther Yi 4, Yujin Park 5 and Philip Mease 6, 1Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Corrona, LLC, Waltham, MA, 3Corrona, LLC, Waltham, 4Novartis Pharmaceuticals Corporation, East Hanover, NJ, 5Novartis Pharmaceuticals Corporation, East Hanover, 6Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA

    Background/Purpose: Secukinumab is the only non–tumor necrosis factor inhibitor biologic therapy approved for the treatment of ankylosing spondylitis (AS) in the United States. Patients with…
  • Abstract Number: 1481 • 2019 ACR/ARP Annual Meeting

    Real-World Use of Apremilast in Combination with Biologic Therapy in Patients with Psoriatic Arthritis: Findings from the Corrona Psoriatic Arthritis/Spondyloarthritis Registry

    Alexis Ogdie1, Mei Liu 2, Meghan Glynn 3, Kelechi Emeanuru 2, Leslie Harrold 4, Sven Richter 5, Benoit Guerette 5 and Philip Mease 6, 1Department of Medicine and Rheumatology and Department of Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 2Corrona, LLC, Waltham, MA, 3Corrona, LLC, Waltham, 4Corrona, LLC and University of Massachusetts Medical School, Worcester, MA, 5Celgene Corporation, Summit, 6Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA

    Background/Purpose: Apremilast (APR), an oral phosphodiesterase 4 inhibitor, demonstrated efficacy in adult patients with active PsA despite prior use of csDMARDs and/or biologics in phase…
  • Abstract Number: 1482 • 2019 ACR/ARP Annual Meeting

    Secukinumab Provides Sustained Improvement of Enthesitis in Ankylosing Spondylitis Patients: A Pooled Analysis of Four Pivotal Phase 3 Trials

    Georg Schett1, Xenofon Baraliakos 2, Filip Van den Bosch 3, Atul Deodhar 4, Lianne Gensler 5, Mikkel Østergaard 6, Shital Agawane 7, Ayan Das Gupta 7, Shephard Mpofu 8, Todd Fox 8, Adam Winseck 9, Brian Porter 9 and Abhijit Shete 8, 1Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany, 2Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, 3Ghent University Hospital, Ghent, Belgium, 4Oregon Health & Science University, Portland, OR, 5University San Francisco California, San Francisco, CA, 6Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark, 7Novartis Healthcare Pvt Ltd, Hyderabad, India, 8Novartis Pharma AG, Basel, Switzerland, 9Novartis Pharmaceuticals Corporation, East Hanover, NJ

    Background/Purpose: Enthesitis can be a debilitating spondyloarthritis (SpA) manifestation and the cause of pain, reduced quality of life and impaired physical function.1,2 Herein, we evaluated…
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