Abstracts Archive - Page 1018 of 2607 - ACR Meeting Abstracts

Abstract Number: 1168 • 2019 ACR/ARP Annual Meeting
Frequently Encountered Artifacts in Novel Application of Dual-Energy CT to Vascular Imaging: A Pilot Study
Chio Yokose¹, Sterling Eide ², F. Joseph Simeone ¹, Kam Shojania ³, Savvas Nicolaou ⁴, Fabio Becce ⁵ and Hyon K. Choi ¹, ¹Massachusetts General Hospital, Boston, MA, ²National University Hospital of Singapore, Singapore, Singapore, ³Vancouver General Hospital, Vancouver, Canada, ⁴Vancouver General Hospital, Vancouver, BC, Canada, ⁵Lausanne University Hospital, Lausanne, Switzerland
Background/Purpose: One hypothesized link between cardiovascular disease and gout is the direct deposition of monosodium urate (MSU) crystals in atherosclerotic plaque. A 2018 ACR abstract…
Abstract Number: 1169 • 2019 ACR/ARP Annual Meeting
Influence of Steroid Treatment on 18F-FDG PET/CT Accuracy to Detect Vascular and Musculoeskeletal Involvement in Patients with Polymyalgia Reumatica
DIANA PRIETO- PENA¹, Mónica Calderón-Goercke ², Isabel Martínez Rodríguez ³, Ignacio Banzo ³, Lara Sanchez-Bilbao ⁴, Iñigo Gonzalez-Mazon ¹, Belén Atienza-Mateo ⁴, Miguel Angel González-Gay ⁵ and Ricardo Blanco ⁴, ¹Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ²Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ³Hospital Universitario Marqués de Valdecilla, Santander, Spain, ⁴Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, ⁵Universidad de Cantabria and IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain
Background/Purpose: Fluorine-18-fluorodeoxyglucose (18F-FDG) PET/CT has been proposed as a promising tool for assessing both musculoskeletal and vascular involvement in patients with polymyalgia rheumatica (PMR). Glucocorticoids…
Abstract Number: 1170 • 2019 ACR/ARP Annual Meeting
Cortical Bone Erosion in the 2nd Metacarpal Bone Head: Association with Its Bone Mineral Density by HR-pQCT in Rheumatoid Arthritis Patients
Camille Figueiredo¹, Mariana Perez ¹, Ana Cristina de Medeiros Ribeiro ², Valeria Caparbo ¹ and Rosa Pereira ³, ¹Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil, ²Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Sao Paulo, Brazil, ³Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil
Background/Purpose: Periarticular trabecular bone loss and local cortical bone erosions are typical features of bone disease in rheumatoid arthritis (RA) 1 . Little, however, is…
Abstract Number: 1171 • 2019 ACR/ARP Annual Meeting
Evidence of Subclinical Joint Inflammation of Hands by Magnetic Resonance Imaging in Patients with Psoriatic Arthritis in Minimal Disease Activity – Interim Analysis
Victoria Furer¹, Ari Polachek ², Liran Mendel ¹, David Levartovsky ³, Jonathan Wollman ⁴, Valerie Aloush ⁵, Ilana Kaufman ⁶, Hagit Sarbagil-Maman ⁷, Sara Borok ⁶, Mark Berman ⁶, Adi Broyde ⁶, Yael Lahat ¹, Mirna Zureik ¹, Sharon Nevo ¹, Daphna Paran ⁶, Iris Eshed ⁸ and Ori Elkayam ⁶, ¹Sourasky Medical Center, Tel-Aviv, Israel, ²Tel-Aviv Sourasky medical center, Tel Aviv, Israel, ³Sourasky medical center, Tel Aviv, Israel, ⁴Sourasky Medical Center, Herzelia, Israel, ⁵Tel Aviv Sourasky medical center, Tel Aviv, ⁶Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁷Tel-Aviv Sourasky medical center, Qiryat-Ono, Israel, ⁸Sheba Medical Center, Tel Aviv, Israel
Background/Purpose: Subclinical inflammatory lesions detected by MRI are prevalent in hand joints of patients with cutaneous psoriasis (1). Yet, it is unknown whether these inflammatory…
Abstract Number: 1172 • 2019 ACR/ARP Annual Meeting
The Relationship Between Subclinical Inflammation and Bone Damage in Patients with Rheumatoid Arthritis Using Multimodality Imaging
Scott Brunet ¹, Peter Salat ², Glen Hazlewood ³, Klaus Engelke ⁴, Cheryl Barnabe ³ and Sarah Manske³, ¹University of Calgary, Calgary, Canada, ²University of Calgary, Calary, Canada, ³University of Calgary, Calgary, AB, Canada, ⁴Erlangen University Hospital, Department of Medicine, Erlangen, Germany
Background/Purpose: Many RA patients in clinical remission have evidence of bone marrow edema (BME) on magnetic resonance imaging (MRI), with radiographic bone damage progression appearing…
Abstract Number: 1173 • 2019 ACR/ARP Annual Meeting
Magnetic Resonance Imaging in Patients in Clinical Remission: Tenosynovitis and Osteitis Are Independent Predictors of Radiographic and MRI Damage Progression
Signe Møller-Bisgaard¹, Kim Hørslev-Petersen ², Bo Ejbjerg ³, Merete Lund Hetland ⁴, Lykke Midtbøll Ørnbjerg ¹, Daniel Glinatsi ¹, Jakob Møller ⁵, Mikael Boesen ⁶, Kristian Stengaard-Pedersen ⁷, Ole Rintek Madsen ⁸, Bente Jensen ⁹, Jan Alexander Villadsen ¹⁰, Ellen-Margrethe Hauge ⁷, Philip Bennett ¹¹, Oliver Hendricks ¹², Karsten Asmussen ⁹, Marcin Kowalski ¹³, Hanne Lindegaard ¹⁴, Henning Bliddal ¹⁵, Niels Steen Krogh ¹⁶, Torkell Ellingsen ¹⁷, Agnete Nielsen ¹⁸, Lone Balding ⁵, Anne Grethe Jurik ¹⁹, Henrik Thomsen ⁵ and Mikkel Østergaard ²⁰, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark, Copenhagen, Denmark, ²Department of Rheumatology, King Christian X’s Hospital for Rheumatic Diseases Graasten, Denmark, Graasten, Denmark, ³Department of Rheumatology, Zealand University Hospital, Køge, Denmark, Køge, Denmark, ⁴DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ⁵Department of Radiology, Herlev and Gentofte University Hospital, Herlev, Denmark, Copenhagen, Denmark, ⁶Department of Radiology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, ⁷Department of Rheumatology, Department of Clinical Medicine, Aarhus University Hospital, Aarhus University, Aarhus, Denmark, Aarhus, Denmark, ⁸Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, ⁹Department of Rheumatology, Bispebjerg and Frederiksberg University Hospital, Frederiksberg, Denmark, Copenhagen, Denmark, ¹⁰Department of Rheumatology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, ¹¹Center for Rheumatology and Spine Diseases, Copenhagen University Hospital Gentofte, Hellerup, Denmark, Copenhagen, Denmark, ¹²Danish Hospital for Rheumatic Diseases, Sønderborg, Denmark, Sønderborg, Denmark, ¹³Department of Rheumatology, Hjørring Hospital, Hjørring, Denmark, Hjørring, Denmark, ¹⁴Department of Rheumatology, Odense University Hospital, Odense, Denmark, Odense, Denmark, ¹⁵The Parker Institute, Copenhagen University Hospital Bispebjerg-Frederiksberg, Copenhagen, Denmark, Copenhagen, Denmark, ¹⁶Zitelab / DANBIO, Copenhagen, Denmark, ¹⁷Department of Rheumatology, Odense University Hospital, Denmark, Odense, Syddanmark, Denmark, ¹⁸Department of Radiology, Silkeborg Hospital, Silkeborg, Denmark, Silkeborg, Denmark, ¹⁹Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, Aarhus, Denmark, ²⁰Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Progression of structural joint damage develops in 20-30 % of patients with rheumatoid arthritis (RA) in clinical remission1. Known predictors of structural damage progression…
Abstract Number: 1174 • 2019 ACR/ARP Annual Meeting
Prevalence of Subclinical Sacroiliitis in Young Patients with Inflammatory Bowel Disease Revealed by Entero-MRI
Teresa Giani¹, Marco Di Maurizio ², Paolo Lionetti ², Azzurra Bernardini ², Giovanna Ferrara ¹, Viola Filistrucchi ² and Rolando Cimaz ³, ¹Anna Meyer Children University Hospital, Florence, Italy, ²A. Meyer Children University Hospital, Florence, Italy, ³Meyer Children's Hospital in Florence, Florence, Italy
Background/Purpose: Sacroiliitis is one of the extraintestinal manifestations associated with inflammatory bowel disease (IBD), and may be underdiagnosed especially in the pediatric age. MR-enterography (Entero-MRI)…
Abstract Number: 1175 • 2019 ACR/ARP Annual Meeting
Periarticular Inflammation and Bone Marrow Oedema Are Important in the Evaluation of Enthesitis on MRI in Patients with Peripheral and Axial SpA
Xenofon Baraliakos¹, Philipp Sewerin ², Eugenio de Miguel ³, Christine Kleinmond ⁴, Ankita Shekhawat ⁵, Annette Wiedon ⁶ and Frank Behrens ⁷, ¹Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, ²Department of Rheumatology & Hiller Research Unit, University Hospital Düsseldorf,, Duesseldorf, Germany, ³Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ⁴ClinProject GmbH, Eurasburg, Germany, ⁵Novartis Healthcare Pvt. Ltd., Hyderabad, India, ⁶Novartis Pharma GmbH, Nürnberg, Germany, ⁷CIRI/Rheumatology and Fraunhofer TMP, Goethe-University, Frankfurt, Germany
Background/Purpose: Enthesitis is a hallmark feature of Spondyloarthritis (SpA), and frequently localizes at the Achilles tendon1. Enthesitis is predominantly measured with clinical scores like Leeds…
Abstract Number: 1176 • 2019 ACR/ARP Annual Meeting
Development and Validation of a Preliminary MRI Sacroiliac Joint Composite Structural Damage Score in a 5-year Longitudinal Study of Patients with Axial Spondyloarthritis
Marie Wetterslev¹, Mikkel Østergaard ², Inge Juul Sørensen ³, Ulrich Weber ⁴, Anne Gitte Loft ⁵, Gina Kollerup ⁶, Lars Juul ⁶, Gorm Thamsborg ⁶, Ole Rintek Madsen ⁷, Jakob Møller ⁸ and Susanne Juhl Pedersen ³, ¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen Ø, Hovedstaden, Denmark, ²Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark, ³Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark, ⁴Danish Hospital for Rheumatic Diseases, Soenderborg, Denmark, Gråsten, Syddanmark, Denmark, ⁵Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, Århus, Denmark, ⁶Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark, ⁷Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, ⁸Department of Radiology, Herlev and Gentofte University Hospital, Herlev, Denmark, Copenhagen, Denmark
Background/Purpose: In patients with axial spondyloarthritis (axSpA), MRI reliably detects structural lesions in the sacroiliac joints (SIJs). The SPARCC Sacroiliac joint (SIJ) Structural Score (SSS)(1)…
Abstract Number: 1177 • 2019 ACR/ARP Annual Meeting
Near Infrared Indocyanine Green Imaging Reveals Altered Anatomy and Diminished Function in Lymphatic Vessels in the Hands of Rheumatoid Arthritis Patients During Flare
Richard Bell¹, Homaira Rahimi ², Alicia Lieberman ², Ronald Wood ², Edward Schwarz ³ and Christopher Ritchlin ⁴, ¹University of Rochester Medical Center, Rochester, NY, ²University of Rochester Medical Center, Rochester, ³University of Rochester, Rochester, NY, ⁴Division of Allergy, Immunology and Rheumatology, Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY, USA, Rochester, NY
Background/Purpose: Near infrared (NIR) imaging of indocyanine green (ICG) in rheumatoid arthritis (RA) models identified abnormal lymphatic vessel (LV) function, which can be quantified as…
Abstract Number: 1178 • 2019 ACR/ARP Annual Meeting
Clinical Utility of DECT in the Diagnosis of Gout at Mayo Clinic in Florida
Emily Gilbert¹, Hillary Garner ¹ and Andy Abril ¹, ¹Mayo Clinic, Jacksonville, FL
Background/Purpose: Gout is the most common inflammatory arthritis in the United States and worldwide. Precipitation of monosodium urate crystals in joints and soft tissues leads…
Abstract Number: 1179 • 2019 ACR/ARP Annual Meeting
Resting-State Functional Connectivity of Pain Processing Brain Region Associated with Therapeutic Response to Biologics in Rheumatoid Arthritis and Spondyloarthritis
Nobuya Abe¹, Yuichiro Fujieda ¹, Kuniyuki Asou ¹, Kohei Karino ², Michihito Kono ³, Hisashi Narita ⁴, Masaru Kato ¹, Khin Tha ⁵, Kenji Oku ¹, Olga Amengual ¹, Shinsuke Yasuda ¹ and Tatsuya Atsumi ⁶, ¹Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ²Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ³Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan, ⁴Department of Psychiatry, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ⁵Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, Sapporo, Japan, ⁶Hokkaido University, Sapporo, Japan
Background/Purpose: Background/Purpose: Discriminating inflammatory pain from non-inflammatory pain is critical to determine therapeutic strategy in inflammatory arthritis (IA) such as rheumatoid arthritis (RA) and spondyloarthritis…
Abstract Number: 1180 • 2019 ACR/ARP Annual Meeting
Confirmation of Manual Cartilage Segmentation Findings by Automated Segmentation: Retrospective Analysis of MRI Images from a Sprifermin Phase II Study
Alan Brett¹, Michael A Bowes ¹, Philip G Conaghan ², Christoph Ladel ³, Jeffrey Kraines ⁴, Hans Guehring ³, Flavie Moreau ⁴ and Felix Eckstein ⁵, ¹Imorphics, Manchester, United Kingdom, ²Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds & NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, ³Merck KGaA, Darmstadt, Germany, ⁴EMD Serono Research and Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA, ⁵Paracelsus Medical University, Salzburg, Austria
Background/Purpose: Sprifermin is under investigation as a potential disease-modifying osteoarthritis drug (DMOAD). 2-yr results from the FORWARD study showed significant dose-dependent modification of cartilage thickness…
Abstract Number: 1181 • 2019 ACR/ARP Annual Meeting
Tocilizumab in Aortitis: A Multicenter Study of 79 Patients
Mónica Calderón-Goercke¹, Javier Loricera ², DIANA PRIETO- PENA ³, Vicente Aldasoro Caceres ⁴, Santos Castañeda ⁵, Ignacio Villa ⁶, Alicia Humbría ⁷, Clara Moriano ⁸, Susana Romero-Yuste ⁹, Javier Narváez ¹⁰, Catalina Gómez-Arango ¹¹, Eva Perez Pampín ¹², Rafael Melero ¹³, Marcelino Revenga ¹⁴, Noelia Álvarez-Rivas ¹⁵, Francisca Sivera ¹⁶, María Álvarez del buergo ¹⁷, Luisa Marena-Rojas ¹⁸, Eva Galindez-Agirregoikoa ¹⁹, Beatriz Arca ²⁰, Roser Solans-Laqué ²¹, Carlos Vazquez ²², Pau Lluch ²³, Eva salgado-Pérez ²⁴, Cristina Luna-Gómez ²⁵, F. Javier Toyos-Sáenz De Miera ²⁶, Nagore Fernández-Llanio ²⁷, Antonio García ²⁸, Carmen Larena ²⁹, Lara Sanchez-Bilbao ¹, Iñigo Gonzalez-Mazon ³, Natalia Palmou-Fontana ³, Vanesa Calvo-Río ¹, Carmen González-Vela ¹, Alfonso Corrales ³⁰, María Varela-García ⁴, Elena Aurrecoechea ⁶, Raquel Dos Santos ³¹, Sabela Fernández ²⁰, Jose Luis Hernández ¹, Miguel Angel González-Gay ³² and Ricardo Blanco ³³, ¹Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ²Rheumatology Department. Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ³Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ⁴Complejo Hospitalario de Navarra, Navarra, Navarra, Spain, ⁵Rheumatology Department, Hospital Universitario de la Princesa, IIS-Princesa, Madrid, Spain, Madrid, Spain, ⁶Hospital de Sierrallana, Torrelavega, Cantabria, Spain, ⁷Hospital de La Princesa, Madrid, Madrid, Spain, ⁸Complejo Asistencial Universitario de León, León, Castilla y Leon, Spain, ⁹Complejo Hospitalario Universitario Pontevedra, Pontevedra, Galicia, Spain, ¹⁰Rheumatology Department, Hospital Universitario de Bellvitge, Barcelona, Spain, Barcelona, Catalonia, Spain, ¹¹Hospital Alto Deba, Mondragon, Pais Vasco, Spain, ¹²Division of Rheumatology, Instituto de Investigación Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain, Santiago de Compostela, Spain, ¹³Complexo Hospitalario Universitario de Vigo, Vigo, Galicia, Spain, ¹⁴Hospital Ramón y Cajal, Madrid, Madrid, Spain, ¹⁵Hospital Universitario Lucus Augusti, Lugo, Galicia, Spain, ¹⁶Hospital General Universitario de Elda, Elda, Spain, ¹⁷Hospital Río Carrión, Palencia, Castilla y Leon, Spain, ¹⁸Hospital La Mancha Centro, Alcázar de San Juan, Castilla-La Mancha, Spain, ¹⁹Hospital de Basurto, Bilbao, Pais Vasco, Spain, ²⁰Hospital Universitario San Agustín, Avilés, Asturias, Spain, ²¹Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona, Spain., Barcelona, Catalonia, Spain, ²²Hospital Miguel Servet, Zaragoza, Aragon, Spain, ²³Hospital Mateu Orfila, Menorca, Islas Baleares, Spain, ²⁴Complejo Hospitalario Universitario de Ourense, Ourense, Galicia, Spain, ²⁵Hospital Universitario Nuestra Señora de la Candelaria, Tenerife, Canarias, Spain, ²⁶Hospital Universitario Virgen Macarena, Sevilla, Andalucia, Spain, ²⁷Hospital Arnau de Vilanova, Lérida, Catalonia, Spain, ²⁸Hospital Virgen de las Nieves, Granada, Andalucia, Spain, ²⁹Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain, ³⁰Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain, Santander, Spain, ³¹Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Galicia, Spain, ³²Universidad de Cantabria and IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ³³Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain
Background/Purpose: Aortitis can be idiopathic or associated with other conditions. It is frequently refractory to conventional immunosuppressive therapy. Tocilizumab (TCZ), an anti-IL-6 receptor antibody seems…
Abstract Number: 1182 • 2019 ACR/ARP Annual Meeting
Fluorescence Optical Imaging in the Diagnosis of Individuals Suspected of Arthritis Development – a Probabilistic Approach
Yogan Kisten¹, Adrian Levitsky ¹, Hamed Rezaei ¹, Aase Hensvold ², Per Larsson ³, Erik af Klint ¹, Ronald van Vollenhoven ⁴ and Anca Catrina ⁵, ¹Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, Stockholms Lan, Sweden, ²Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, ³Center for Rheumatology, Academic Specialist Center, Stockholm Health Services, Stockholm, Sweden, Stockholm, Stockholms Lan, Sweden, ⁴Amsterdam Rheumatology and immunology Center, Netherlands., Amsterdam, Netherlands, ⁵Rheumatology unit Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden, Stockholm, Sweden
Background/Purpose: Among the arsenal of available techniques for arthritis prediction and diagnosis, fluorescence optical imaging (FOI) has shown to be useful in detecting clinically manifest…

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