ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstract Number: 0668

Outcomes and Resource Utilization After Total Knee Arthroplasty in Calcium Pyrophosphate Crystal Deposition Disease Patients: Insights from the National Inpatient Sample Database

Konstantinos Parperis1, Mohanad Hadi2 and Bikash Bhattarai3, 1University of Arizona College of Medicine Phoenix and University of Cyprus Medical School, Phoenix, 2Creighton University - Maricopa Medical Center/ Valleywise Health Medical Center, Phoenix, AZ, 3Valleywise Health, University of Arizona College of Medicine, Phoenix, AZ

Meeting: ACR Convergence 2020

Keywords: Arthroplasty, CPPD

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print
Session Information

Date: Saturday, November 7, 2020

Title: Metabolic & Crystal Arthropathies Poster

Session Type: Poster Session B

Session Time: 9:00AM-11:00AM

Background/Purpose: Total knee arthroplasty (TKA) is one of the most frequently performed orthopedic procedures in patients with joint cartilage destruction. Calcium pyrophosphate crystal deposition (CPPD) disease is a crystal-induced arthropathy characterized by the deposition of calcium pyrophosphate crystals in the articular and periarticular tissues that might lead to inflammatory arthritis, joint damage and the need for TKA. No prior studies exist evaluating the outcomes of CPPD patients after TKA. We aim to determine the in-hospital complications, mortality, and resource utilization following TKA in patients with and without CPPD.

Methods: We queried the US National Inpatient Sample (NIS) Database from 2009-2014 in order to identify patients who had TKA. The ICD-9 code was used to identify the patients who underwent primary TKA (81.54, V43.65), and of those, we classified the patients into two groups: (i) with ICD-9 codes defining CPPD (275.49 and 712.1–712.39) and (ii) those without any CPPD code. Data collection included patient demographics and co-morbidities. Outcomes after-TKA were in-hospital mortality, length of hospitalization, hospital charges, in-hospital complications such as surgical site infections, blood loss and need for transfusion, re-operation, thromboembolism, popliteal artery injury, peroneal nerve palsy. Associations between CPPD and specific morbidity were evaluated with chi-square tests. Wilcoxon rank-sum tests were used for continuous variables.

Results: Among the 4,180,274 (adjusted for sampling weight) patients who have undergone TKA during the 7-year period (2009-2014), 7660 (0.18%) had CPPD, with a median age of 73 years and 57.9% were females (Table). Compared with patients without CPPD, patients with CPPD patients were more likely to be older (median age78  vs 73 years; p< 0.0001). Co-morbidities that were more frequent among CPPD patients included chronic kidney disease, gout and knee fracture. Regarding postoperative complications, the need for re-operation was significantly more common in CPPD patients (p < 0.0001). Further, TKA in CPPD patients was associated with prolonged median length of stay than those without CPPD (4 vs 3 days; p < 0.0001), although the median total charges were higher in the CPPD group, this finding was not statistically significant ($30,718 vs $30,272; p=0.44). The in-hospital mortality was lower in the CPPD patients (0.65 vs 1.2; p< 0.001).

Conclusion: To our knowledge, this the first study demonstrating that patients with CPPD patients who had undergone TKA were more likely to be older than those without CPPD, had increased length of stay; however, the in-hospital mortality was lower. These findings merit further study.


Disclosure: K. Parperis, None; M. Hadi, None; B. Bhattarai, None.

To cite this abstract in AMA style:

Parperis K, Hadi M, Bhattarai B. Outcomes and Resource Utilization After Total Knee Arthroplasty in Calcium Pyrophosphate Crystal Deposition Disease Patients: Insights from the National Inpatient Sample Database [abstract]. Arthritis Rheumatol. 2020; 72 (suppl 10). https://acrabstracts.org/abstract/outcomes-and-resource-utilization-after-total-knee-arthroplasty-in-calcium-pyrophosphate-crystal-deposition-disease-patients-insights-from-the-national-inpatient-sample-database/. Accessed .
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

« Back to ACR Convergence 2020

ACR Meeting Abstracts - https://acrabstracts.org/abstract/outcomes-and-resource-utilization-after-total-knee-arthroplasty-in-calcium-pyrophosphate-crystal-deposition-disease-patients-insights-from-the-national-inpatient-sample-database/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology