Is
it possible to identify psoriasis patients who will develop axial disease? Real life data from PsART (Psoriatic Arthritis Registry of Turkey)

S. Z. Aydýn, Ö. Bayýndýr ¹  , B.
Yýlmazer ¹,K. Aksu ¹, E. Dalkýlýç ¹, M. F.
Öksüz ¹, E. F. Tarhan ¹, M. Can ¹, O.
Küçükþahin ¹ , G. Kimyon ¹, L. Akyol ¹, A. M.
Onat ¹, B. Kýsacýk ¹, A. Erden ¹, A. Omma ¹,
E. D. Ersözlü Bozkýrlý ¹, C. Öziþler ¹, E. Gönüllü ¹
, S. Masatlýoglu Pehlevan ¹, D. Solmaz ¹, M. Çýnar ¹,
G. Yýldýrým Çetin ¹, A. Tufan ¹, M. Aydýn Tufan ¹,
L. Kýlýç ¹, S. Erten ¹, T. Kaþifoglu ¹, S.
Kobak ¹, S. Þenel ¹, S. Akar ¹, M. Özgen ¹,
E. Kasapoglu Günal ¹, V. Yazýsýz ¹, S. Yýlmaz ¹,
S. Dönmez ¹, I. Dogan ¹, H. Kart Köseoglu ¹,
F. Erbasan ¹, F. Yýldýz ¹, C. Bes ¹, A.
Balkarlý ¹, A. Þahin ¹, R. Mercan ¹, F. Arslan
¹, A. Dogru ¹, S. Pay ¹, S. Yavuz ¹,
N. Çakýr ¹, Y. Kabasakal ¹, U. Kalyoncu

¹PsART
study group, Ankara, Turkey

Background/Purpose:Psoriatic arthritis (PsA) is a complex disease with various patterns
of joint involvement. PsART (Psoriatic Arthritis
Registry of Turkey) is a prospective,
multicentre, nationwide study in Turkey which was built with the objective of understanding the nature of the disease, clarify differences
among different presentation types of PsA and identifying poor prognostic factors.
Here we present the cross sectional characteristics of
a large group of PsA patients from the registry, with an emphasis on factors
associated with axial disease.

Methods: PsART was built in May 2014. Patients are consecutively recruited to
this registry, if they are diagnosed as PsA, regardless of any disease
characteristics. Data collection was performed through a website. Disease
characteristics, treatments and comorbidities were collected in addition to
disease activity and function assessment.

Results: Until June 2015, 1060 patients were recruited. Within these 64.5 % (684/1060)
were female.. The mean (SD) duration of PsA was 77.7 (89) months. Arthritis was
the initial finding in 4.4% and psoriasis preceded in 85.8% (Table).  Patients
with axial involvement were significantly younger than the other forms of
arthritis (p<0.0001). Other factors that were associated with axial disease
were type of psoriasis (pustular type 31.4% in axial disease vs 21.4 in
non-axial forms; p=0.008), smoking (43.7% vs 33.3%; p=0.008) and having nail
disease (53.3% vs 44.6%; 0.013).

Patients who had
pustular type of psoriasis, nail disease and smoked had a 1.86 relative risk
for having axial disease compared to patients who doesn’t have at least one
them.

Conclusion: The patient characteristics of the PsART are comparable to the
previously reported registries, supporting its external validity.  The pattern
of arthritis may be foreseen in patients with pustular type of psoriasis and
nail disease especially if they have a history of smoking.

Table: Characteristics of PsA patients from
PsART. *: data given as mean (SD).