Session Information
Date: Sunday, November 8, 2015
Session Type: ACR Poster Session A
Session Time: 9:00AM-11:00AM
Background/Purpose: Adult rheumatologist assess conditions in patients aged 18 and above. There is no distinction to those of the frail age of 65 and above who could belong to a geriatric rheumatology group. Aims:To assess whether there are differences between psoriatic arthritis (PsA) patients aged above 65 years (y). To compare demographic, (gender ratio, ethnicity, social habits) disease characteristics, activity and function( disease duration, delay in diagnosis, ESR, CRP, Night pain, sleep disturbance, BASDAI, BASFI) and treatment (Tx)options as wells as treatment effect, and well being over past week (wbpw) and over past 6 months (wb6m) of those above 65y with those aged below 45y.
Methods: From total 719 patients (pts) with Spondyloarthritis (SpA) registered in the London Registry of SpA (LoRoS) which has been developed aiming to assess differences in SpAs between ethnic groups over time, (ethics approval REC 07/H0701/74) 247 pts had confirmed PsA by CASPAR. From the total of 247 pts, 45 pts had their baseline characteristics recorded at age 65y (or above) and formed the Gero PsA group (gPsA) which has been analysed and compared with those patients who entered in the registry at age below45y (b45) (n=73). The remaining patients belonging in the intermediate age group of between 45 to 64 (intag)(n=124) has been analysed where there were discrepancies.
Results: Table shows the disease characteristics of the geroPsA group compared with those of below 45, ssd and CI. The statistically significant difference(ssd) between the ethnic groups studied in our cohort compatible with national ethnic migration reports. Smoking reported by more b45 but did not reach ssd. There was no difference in the Tx between the gPsA and the b45 except a borderline difference in the Tx with Sulphasalazine (SSZ)in that more pts b45 were on SSZ [P=0.08 (CI= -0.21 to 0.18)] while more gPsA patients had joint surgery (p=0.01; CI=0.065 to 0.45).
Conclusion: PsA patients above the age of 65y have differences compared with the younger age group and can form a distinct geriatric PsA group. Differences identified in our cohort were related to ethnicity, social habits, inflammatory markers, function and treatment options and effect.
| Items |
Gero PsA(n=45) mean (sd) |
Below45y (n=73) mean (sd) |
Pvalues | CI (lower to upper |
| Gender | 16:29(1:2) | 24:49(1:2) | n/a | |
| Ethnic group |
Caucasian=38/45 (84.4%) Asian =3/45 (6.6%) African =4/45 (8.8) |
caucasian=38/73 (52%) Asian=29/73 (42.4%) African=3/73 (4%) mixed race 1/73 |
p=0.03 p=0.04 p=0.7 |
|
| Alcohol intake | 57.7% | 46.5% | p=0.02 | 0.0028 to 0.44 |
| Delay in diagnosis (years) | 9.4 (15.3) | 3.3 (3.9) | p=0.05 | 0.002 to 12.2 |
| Disease duration | 11.9 (15.5) | 4.6 (4.2) | p=0.02 | 1.1 to 13.4 |
| ESR | 23.7 (19) | 19.1(22) | p=0.2 | =3.1 to 12.3 |
| CRP | 7.6 (6.8) | 7.6(6.6) | p=0.9 | -3.3 to 3.2 |
| Night Pain | 3.9(3.3) | 5.4(3) | p=0.06 | -3.2 to 0.09 |
| Sleep disturbance | 3.9 (3.3) | 5.3(3.2) | p=0.1 | -3.4 to 0.48 |
| BASDAI score | 5.2(2.3) | 6.06(2.2) | p=9.1 | -2.07 to 0.3 |
| BASFI score | 5.63 (2.7) | 4.09(2.6) | p=0.02 | 0.23 to 2.85 |
| Treatment effect (VAS) perceived | 5.1(2.7) | 4.04(2.04) | p=0.08 | -0.17 to 2.3 |
| Well being past week | 4.58(2.8) | 5.46(2.7) | p=0.1 | -2.17 to 0.41 |
To cite this abstract in AMA style:
Roussou E. Is a Geriatric Rheumatology Sub-Group Worth Distinguishing? Disease Characteristics of a Geriatric Psoriatic Arthritis (Gero PsA) Subgroup Compared with Those of below 45 Years of Age [abstract]. Arthritis Rheumatol. 2015; 67 (suppl 10). https://acrabstracts.org/abstract/is-a-geriatric-rheumatology-sub-group-worth-distinguishing-disease-characteristics-of-a-geriatric-psoriatic-arthritis-gero-psa-subgroup-compared-with-those-of-below-45-years-of-age/. Accessed .« Back to 2015 ACR/ARHP Annual Meeting
ACR Meeting Abstracts - https://acrabstracts.org/abstract/is-a-geriatric-rheumatology-sub-group-worth-distinguishing-disease-characteristics-of-a-geriatric-psoriatic-arthritis-gero-psa-subgroup-compared-with-those-of-below-45-years-of-age/