Increased Carotid Intima-Media Thickness in Psoriatic Arthritis Patients Compared with Systemic Lupus Erythematosus Patients and Healthy Controls

Handan Yarkan¹, Aslıgul Dunya², Pinar Cetin¹, Gercek Can¹, Nurullah Akkoc³ and Fatos Onen¹, ¹Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, ²Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, ³Department of Rheumatology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey

Meeting: 2015 ACR/ARHP Annual Meeting

Date of first publication: September 29, 2015

Keywords: Cardiovascular disease, psoriatic arthritis and systemic lupus erythematosus (SLE)

Session Information

Date: Monday, November 9, 2015

Title: Spondylarthropathies and Psoriatic Arthritis - Comorbidities and Treatment Poster II

Session Type: ACR Poster Session B

Session Time: 9:00AM-11:00AM

Background/Purpose: The aim of this study was to investigate carotid intima-media thickness (IMT) in patients with psoriatic arthritis (PsA) and compare it with those in patients with systemic lupus erythematosus (SLE) and healthy controls (HC).

Patients and Methods: Non-diabetic patients with PsA and age and body mass index (BMI) matched patients with SLE were included. Bilateral carotid IMTs were evaluated by using B-mode ultrasonography in PsA patients and compared with those in controls.

Results: There were 42 PsA patients (30 female, 12 male; mean age: 45.36 ± 8.9 years) who fulfilled CASPAR criteria and 38 patients (37 female, 1 male; 41.2± 13.0 years) who fulfilled the 1982 revised ACR criteria for SLE. Thirthy healthy hospital workers (27 female, 3 male; mean age 41.2 ± 6.8 years) were recruited as HC. The frequency of hiperlipidemia was found to be significantly higher in patients with PsA than SLE patients and HC (p<0.001) but hypertension was more common in SLE patients (p=0.002). The averaged carotid IMT was found to be higher in PsA patients in comparison with the SLE patients and HC (p<0.001).

Conclusion: This study showed that carotid IMT measurements were higher in PsA patients than SLE patients and HC.

Table 1. B-mode ultrasonography results in the study subjects

	Averaged CCA IMT (mm)	Right CCA IMT (mm)	Left CCA IMT (mm)
PsA patients (n:42)	0.76 ± 0.15*	0.72 ± 0.12*	0.79 ± 0.18*
SLE patients (n:38)	0.58 ± 0.11	0.56 ± 0.12	0.60 ± 0.12
Healthy controls (n:30)	0.57 ± 0.12	0.55 ± 0.12	0.59 ± 0.15

Data are mean ± SD (*p<0.001 for PsA patients vs SLE patients and healthy controls). CCA: common carotid artery

Disclosure: H. Yarkan, None; A. Dunya, None; P. Cetin, None; G. Can, None; N. Akkoc, None; F. Onen, None.

To cite this abstract in AMA style:

Yarkan H, Dunya A, Cetin P, Can G, Akkoc N, Onen F. Increased Carotid Intima-Media Thickness in Psoriatic Arthritis Patients Compared with Systemic Lupus Erythematosus Patients and Healthy Controls [abstract]. Arthritis Rheumatol. 2015; 67 (suppl 10). https://acrabstracts.org/abstract/increased-carotid-intima-media-thickness-in-psoriatic-arthritis-patients-compared-with-systemic-lupus-erythematosus-patients-and-healthy-controls/. Accessed .

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