ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstract Number: 2026

High Prevalence of Cervical Spine and Temporomandibular Joint Involvement in Patients with Juvenile Idiopathic Arthritis

Nikolay Tzaribachev1, Catrin Tzaribachev1 and Bernd Koos2, 1Pediatric Rheumatology, Center for Rheumatic Diseases, Bad Bramstedt, Germany, 2Clinic of Orthodontics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany

Meeting: 2012 ACR/ARHP Annual Meeting

Keywords: Cervical spine, juvenile idiopathic arthritis (JIA), magnetic resonance imaging (MRI) and temporomandibular joint

  • Tweet
  • Email
  • Print
Session Information

Title: Pediatric Rheumatology - Clinical and Therapeutic Aspects: Juvenile Idiopathic Arthritis and Other Pediatric Rheumatic Diseases

Session Type: Abstract Submissions (ACR)

Background/Purpose:   Detection of involvement of temporomandibular joints (TMJ), which are frequently affected by juvenile idiopathic arthritis (JIA), is only possible on Gadolinium enhanced MRI (GdMRI). A comparative X-ray study on adults with JIA and RA showed a more frequent involvement and destruction of the dens axis in JIA patients. The aim of the retrospective study was to evaluate the involvement of the cervical spine (CS) in children with JIA.

Methods:  The first GdMRI TMJ examinations of consecutive patients with defined JIA from our center were re-evaluated for involvement of the cervical spine (dens axis, DA). Clinical parameters were recorded – CS pain on motion, CS limited range of motion (LOM), peripheral disease activity (PDA, peripheral active, painful and LOM joints) and medication. MRI examinations were re-evaluated for TMJ and dens axis arthritis defined as synovitis and synovial hypertrophy.

Results: 40 children (29 female) were included. 21 patients had RF neg. polyarthritis,  oligoarthritis was present in 11, ERA and PsA in 4 children equally. Median age at GdMRI was 14 (7-18) years. Median disease duration was 36 (4-192) months. At first GdMRI 47% were on NSAIDs with a median duration of 10 (1-36) months, 49% were on MTX (sc 10-15 mg/m2) with a median duration of 12 months and 13 patients were on TNF Alpha inhibitors with a median duration of 3 (2-12) months. 10 patients showed no PDA but of these only one had no inflammation in DA and TMJ on GdMRI. 34 patients had arthritis in DA (25) or TMJ (33) and 25 patients had arthritis in both DA and TMJ. Out of all patients only 8 had pain and/or LOM of the CS, which were always correlated with arthritis in TMJ and DA on GdMRI. In all other patients CS involvement was silent. Current medication was not able to control disease activity.

Conclusion: considering that long-term sequels of CS arthritis in adults with JIA tend to be more severe than in RA patients, the high frequency of silent CS arthritis should be kept in mind, where GdMRI is the only tool to detect the extent of disease activity of the cervical spine and help with a proper monitoring of the treatment effect.


Disclosure:

N. Tzaribachev,
None;

C. Tzaribachev,
None;

B. Koos,
None.

  • Tweet
  • Email
  • Print

« Back to 2012 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/high-prevalence-of-cervical-spine-and-temporomandibular-joint-involvement-in-patients-with-juvenile-idiopathic-arthritis/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology