HAQ Score Is an Independent Predictor of Sustained Remission in Patients with Rheumatoid Arthritis

Ji-Eun Kim¹, Kyung-Eun Lee², Ji-Hyoun Kang², Yi-Rang Yim¹, Jeong-Won Lee¹, Lihui Wen¹, Dong-Jin Park², Tae-Jong Kim³, Yong-Wook Park² and Shin-Seok Lee³, ¹Chonnam National University Medical School and Hospital, Gwangju, South Korea, ²Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, South Korea, ³Rheumatology, Chonnam National University Medical School and Hospital, Gwangju, Korea, The Republic of

Meeting: 2016 ACR/ARHP Annual Meeting

Date of first publication: September 28, 2016

Keywords: Health Assessment Questionnaire, remission and rheumatoid arthritis (RA)

Session Information

Date: Sunday, November 13, 2016

Title: Rheumatoid Arthritis – Clinical Aspects - Poster I: Clinical Characteristics/Presentation/Prognosis

Session Type: ACR Poster Session A

Session Time: 9:00AM-11:00AM

Background/Purpose: We compared remission rates, according to different definitions of remission in rheumatoid arthritis (RA) and investigated the potential predictors of sustained remission at the 2-year follow-up.

Methods: We obtained data on 291 RA outpatients, seen from July 2009 to September 2012. Sociodemographic data and answers to questionnaires were collected in face-to-face interviews. Remission was defined according to the Disease Activity Score in 28 joints (DAS28)-ESR, DAS28-CRP, Simplified Disease Activity Index (SDAI), Clinical Disease Activity Index (CDAI), and ACR/EULAR Boolean definition. Sustained remission was defined as when the patient continued in remission at two consecutive annual assessments. Predictors of sustained remission according to the DAS28-CRP were assessed by univariate and multivariate analyses.

Results: For the 291 RA patients, the remission rates of RA were 17.9% (DAS28-ESR), 54.3% (DAS28-CRP), 10.3% (SDAI), 10.0% (CDAI), and 5.8% (Boolean). On follow-up for 2 years, the sustained remission rates of RA were 46.5% (DAS28), 55.0% (DAS28-CRP), 37.5% (SDAI), 32.0% (CDAI), and 30.8% (Boolean). RA patients who achieve sustained remission according to the DAS28-CRP were younger, and had more education, higher monthly income, lower Health Assessment Questionnaire (HAQ) score, lower physician global assessment, lower patient global assessment, lower patient pain assessment, and higher EQ-5D. In multivariate analysis, only the HAQ score predicted sustained remission according to DAS28-CRP (OR=0.257, 95% CI 0.067–0.980, p = 0.047).

Conclusion: The remission rates of RA patients differed according to the definition of remission, and the highest sustained remission rate was classified by the DAS28-CRP. A lower HAQ score was an independent predictor of sustained remission over 2 years, according to the DAS28-CRP.

Disclosure: J. E. Kim, None; K. E. Lee, None; J. H. Kang, None; Y. R. Yim, None; J. W. Lee, None; L. Wen, None; D. J. Park, None; T. J. Kim, None; Y. W. Park, None; S. S. Lee, None.

To cite this abstract in AMA style:

Kim JE, Lee KE, Kang JH, Yim YR, Lee JW, Wen L, Park DJ, Kim TJ, Park YW, Lee SS. HAQ Score Is an Independent Predictor of Sustained Remission in Patients with Rheumatoid Arthritis [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/haq-score-is-an-independent-predictor-of-sustained-remission-in-patients-with-rheumatoid-arthritis/. Accessed .

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