Session Information
Session Type: ACR Poster Session A
Session Time: 9:00AM-11:00AM
Background/Purpose:
Foot and ankle structures are commonly affected in gout. People with gout
experience difficulty walking and report high levels of foot pain, disability
and impairment. Despite the importance of lower limb and foot muscle strength requirements
in walking, the strength of foot and ankle muscles in gout is unknown. The
primary aim of this study was to determine differences in foot and ankle muscle
strength for ankle plantarflexion, dorsiflexion, inversion and eversion between
people with gout and age- and sex-matched controls. The secondary aim was to
examine the relationship between foot and ankle muscle strength, and foot pain
and disability.
Methods: Peak
isokinetic concentric muscle torque was measured for ankle plantarflexion, dorsiflexion,
eversion and inversion in 20 participants with gout and 20 matched controls at
two testing velocities (30°/s and 120°/s) using a Biodex
dynamometer. Peak torque was calculated and normalised to body weight. Foot
pain and disability was measured using the Manchester Foot Pain and Disability
Index (MFPDI). Differences in peak torque between gout and control participants
were analysed using mixed linear models. Pearson’s correlation coefficients
were used to determine associations between MFPDI scores and peak torque.
Results: Differences
in peak torque between gout participants and controls are displayed in the
Table below. At both the 30°/s
and 120°/s testing
velocities, participants with gout had lower ankle peak plantarflexion,
inversion, and eversion torque compared with control participants. No
differences between gout and control participants were evinced for peak
dorsiflexion torque at either 30°/s
or 120°/s testing velocities. Mean MFPDI scores were higher in
participants with gout compared to controls (p=0.00001). For participants with
gout, MFPDI scores were inversely correlated with peak plantarflexion torque at
both 30°/s (r=-0.66,
p<0.001) and 120°/s
(r=-0.44, p=0.008), peak eversion torque at the 120°/s testing velocity (r=-0.36,
p=0.045) and peak inversion torque at both 30°/s (r=-0.49, p=0.005)
and 120°/s (r=-0.56, p=0.001) testing velocities.
Conclusion: People
with gout have reduced foot and ankle muscle strength and experience greater
foot pain and disability compared to controls. Foot and ankle strength
reductions are strongly associated with increased foot pain and disability in
people with gout.
|
Table. Mean peak torque and difference between gout and controls, N·m/kg |
||||
|
|
Mean (SD) peak torque |
Difference (95% CI) |
p |
|
|
|
Control |
Gout |
||
|
Plantarflexion 30°/s |
0.94 (0.10) |
0.65 (0.10) |
-0.29 (-0.51, -0.07) |
0.010 |
|
Dorsiflexion 30°/s |
0.41 (0.08) |
0.37 (0.09) |
-0.04 (-0.10, 0.03) |
0.280 |
|
Plantarflexion 120°/s |
0.51 (0.19) |
0.32 (0.19) |
-0.19 (-0.32, -0.05) |
0.008 |
|
Dorsiflexion 120°/s |
0.25 (0.14) |
0.22 (0.14) |
-0.03 (-0.06, 0.01) |
0.111 |
|
Eversion 30°/s |
0.34 (0.07) |
0.24 (0.07) |
-0.09 (-0.16, -0.03) |
0.005 |
|
Inversion 30°/s |
0.37 (0.30) |
0.25 (0.30) |
-0.12 (-0.21, -0.03) |
0.012 |
|
Eversion 120°/s |
0.21 (0.15) |
0.17 (0.15) |
-0.04 (-0.08, -0.01) |
0.028 |
|
Inversion 120°/s |
0.24 (0.48) |
0.17 (0.48) |
-0.07 (-0.12, -0.02) |
0.005 |
To cite this abstract in AMA style:
Stewart S, Mawston G, Davidtz L, Dalbeth N, Vandal A, Carroll M, Morpeth T, Otter S, Rome K. Foot and Ankle Muscle Strength in People with Gout: A Two-Arm Cross-Sectional Study [abstract]. Arthritis Rheumatol. 2015; 67 (suppl 10). https://acrabstracts.org/abstract/foot-and-ankle-muscle-strength-in-people-with-gout-a-two-arm-cross-sectional-study/. Accessed .« Back to 2015 ACR/ARHP Annual Meeting
ACR Meeting Abstracts - https://acrabstracts.org/abstract/foot-and-ankle-muscle-strength-in-people-with-gout-a-two-arm-cross-sectional-study/