ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 2722

Evolution over Thirty Years of the Profile of Inpatients with Reactive Arthritis in a Tertiary Rheumatology Unit

Daniel Wendling1, Anne Brinster2, Xavier Guillot3 and Clément Prati4, 1Rheumatology, Besançon university hospital, Besançon, France, 2Rheumatology, CHRU, Besançon, France, 3EA 4267 FDE, FHU INCREASE, Université de Bourgogne Franche-Comté, Besançon, France, 4Service de Rhumatologie, CHU J Minjoz, Besancon, France

Meeting: 2016 ACR/ARHP Annual Meeting

Date of first publication: September 28, 2016

Keywords:

Session Information

Date: Tuesday, November 15, 2016

Title: Spondylarthropathies and Psoriatic Arthritis – Clinical Aspects and Treatment - Poster III

Session Type: ACR Poster Session C

Session Time: 9:00AM-11:00AM

Background/Purpose: Reactive arthritis (ReA) are sterile arthritis occurring after extra articular bacterial infection, mainly located in gut or genito urethral mucosa. The aim of this study was to analyze, over 30 years, frequency as well as clinico-biological and therapeutic characteristics of inpatients with ReA, comparing two periods.

Methods: In this retrospective monocentric study, the charts of all the patients followed in our unit between January 1st 1984 and April 2014 with the diagnosis or ReA, according to International Classification Criteria (1), were recorded and clinic biological features, management and outcome were analyzed, and compared between two periods : from January 1984 to December 1993, and from January 2004 to December 2013.

Results: 62 patients fulfilling international diagnosis criteria were analyzed. We found no significant differences (Table) between the two periods in frequency of new cases, clinical presentation (rheumatologic and extra articular features), biological and microbiological data or outcome.Change in therapeutic management was obvious with lower delay for DMARD initiation and occurrence of anti TNF use in the recent period.

1984 – 1993 2004 – 2013 p
Number of ReA patients / hospitalizations 15 / 7438 31 / 11 823 NS
Median age at diagnosis 37 30 NS
HLA B27 + (%) / Evidence of infectious agent (%) 91 / 53 63 / 61 NS
Delay between infection/articular symptoms (days) median 5.5 9 NS
CRP (mean) (mg/l) 87 90 NS
TJC / SJC 2.8 / 1.8 3.2 / 2 NS
1984 – 1993 2004 – 2013 p
Enthésitis (%) / Dactylitis (%) 40 / 13 26 / 29 NS
Extra articular features (%) 47 35 NS
Axial symptoms (%) 33 29 NS
DMARDs use (%) 36 62 NS
Median delay of DMARD introduction (days) 210 50.5 NS
Biologic agents use (%) 0 45  0.005
Remission at last follow-up (%) 57 47 NS

Conclusion: Reactive arthritis is still a current rheumatologic problem, with an apparently stable frequency in a developed country, with a need of early and tailored rheumatologic management.

Disclosure: D. Wendling, None; A. Brinster, None; X. Guillot, None; C. Prati, None.

To cite this abstract in AMA style:

Wendling D, Brinster A, Guillot X, Prati C. Evolution over Thirty Years of the Profile of Inpatients with Reactive Arthritis in a Tertiary Rheumatology Unit [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/evolution-over-thirty-years-of-the-profile-of-inpatients-with-reactive-arthritis-in-a-tertiary-rheumatology-unit/. Accessed .

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