ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstract Number: 792

Evaluation of Esophageal Dysmotility in Systemic Sclerosis: Clinical VALUE of Computed Tomography

Cristina Sobrino1, Cristina Pijoan-Moratalla1, Nicolás Almeida-Arostegui2, Luis Gorospe-Sarasúa2 and Carlos de la Puente-Bujidos1, 1Rheumatology Unit. Ramón y Cajal University Hospital, Madrid, Spain, 2Radiology Unit. Ramón y Cajal University Hospital, Madrid, Spain

Meeting: 2018 ACR/ARHP Annual Meeting

Keywords: Computed tomography (CT), Diagnostic imaging, Gastrointestinal complications and systemic sclerosis

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print
Session Information

Date: Sunday, October 21, 2018

Title: Systemic Sclerosis and Related Disorders – Clinical Poster I

Session Type: ACR Poster Session A

Session Time: 9:00AM-11:00AM

Background/Purpose: Esophageal dysmotility is common in Systemic Sclerosis (SSc), affecting 50-80% of patients, usually associated with poor prognosis. SSc leads to atrophy and fibrosis of the smooth muscle of the esophagus, modifying peristaltic contractions and motility. Manometry is considered the gold standard for the diagnosis of esophageal motility disorders, but dilation can also be observed with computed tomography (CT), even if its diagnostic validity is still unknown. /Purpose: To compare esophageal dilation observed with CT to manometry, in patients with SSc and to confirm whether CT can be used in the assessment of esophageal dysmotility.

Methods: Forty six patients meeting the 2013 ACR/EULAR Classification Criteria for SSc, and 53 healthy controls were included and retrospectively studied. Patients with overlapping syndromes, active infections or with longstanding diabetes were excluded. Epidemiological and clinical data were collected from medical records. All patients and controls had undergone at least one manometry and one CT, requested in daily clinical practice for another purpose. The most recent exams were selected for the study. Esophageal involvement was assessed using manometry (aperistalsis, inefficient peristalsis, nonspecific dysmotility and normal peristalsis) and compared with the largest coronal esophageal luminal diameters proximally, near the carina, and distally observed by CT. Data analysis was performed by STATA. All patients signed written informed consent, approved by the Research Ethics Committee.

Results: The sample included 76 women (10 dcSSc, 28 lcSSc, 3 MCTD, 35 controls) and 23 men (3 dcSSc, 2 lcSSc, 18 controls). Esophageal dysmotility was seen in 40/46 patients with SSc (87%) by manometry (defined as inefficient peristalsis or aperistalsis). Esophageal dilation (≥10mm) was present proximally in 23/44 patients (52.3%), distally in 35/46 patients (76.1%), and near the carina in 26/44 patients (59,1%). Esophageal dilatation at any level was statistically associated with esophageal dysmotility (p<0.05). The areas under the ROC curves suggest that the esophageal proximal diameter in the coronal plane is good for detecting esophageal dysmotility (0.798, 95%CI 0.705-0.890), with the distal diameter (0,759, 95% CI 0.661-0.857) and the carinal diameter (0.712, 95%CI 0.607-0.816), being slightly lower. A proximal diameter ≥7.5 mm provides a specificity of 87.2% (95% CI: 76.7–96.7) and a sensitivity of 65.3% (95% CI: 51.9–78.6) for esophageal dysmotility, enabling correct classification of 75% of the patients. A distal diameter ≥12.9 mm provides a specificity of 76.6% (95% CI: 64.5–88.7) and a sensitivity of 71.2% (95% CI: 58.8–83.5), correctly classifying 73% of the patients.

Conclusion: CT, a less invasive technique than manometry, can be an acceptable diagnostic tool for esophageal dysmotility in SSc, when the maximum proximal or distal esophageal diameter are ≧7.5mm and 12.9mm, respectively. CT done in the daily clinical practice could be exploited when manometry is not preferred in selected patients with SSc. More studies need to be carried out to confirm this results.


Disclosure: C. Sobrino, None; C. Pijoan-Moratalla, None; N. Almeida-Arostegui, None; L. Gorospe-Sarasúa, None; C. de la Puente-Bujidos, None.

To cite this abstract in AMA style:

Sobrino C, Pijoan-Moratalla C, Almeida-Arostegui N, Gorospe-Sarasúa L, de la Puente-Bujidos C. Evaluation of Esophageal Dysmotility in Systemic Sclerosis: Clinical VALUE of Computed Tomography [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 9). https://acrabstracts.org/abstract/evaluation-of-esophageal-dysmotility-in-systemic-sclerosis-clinical-value-of-computed-tomography/. Accessed .
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

« Back to 2018 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/evaluation-of-esophageal-dysmotility-in-systemic-sclerosis-clinical-value-of-computed-tomography/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology