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Abstract Number: 70

Data from Brazilian Fibromyalgia Patients Registry (EPIFIBRO) in 2014

Jose Eduardo Martinez1,2, Marcelo C. Rezende3,4, Eduardo Paiva4,5, Daniel Pollak4,6, Milton Helfenstein Jr4,7, Jose Roberto Provenza4,8, Aline Ranzolin4,9, Roberto E Heymann4,10, Eduardo L. Ribeiro4,11, Marcos Renato Assis4,12 and Eduardo J. R. Souza4,13, 1Sociedade Brasileira de Reumatologia, Sorocaba, Brazil, 2Medicine, Pontifical Catholic University of Sao Paulo, Sorocaba, Brazil, 3Santa Casa de Campo Grande, Campo Grande, Brazil, 4Sociedade Brasileira de Reumatologia, São Paulo, Brazil, 5Rheumatology, Universidade Federal do Parana, Curitiba, Brazil, 6Rheumathology, Universidade Federal de São Paulo, São Paulo, Brazil, 7RUA JOAO DE LACERDA SOARES, 90, Unifesp, Sao Paulo, Brazil, 8Rheumatology, Pontifícia Universidade Católica de Campinas, Campinas, Brazil, 9Hospital das Clínicas - Universidade Federal de Pernambuco, Recife, Brazil, 10Universidade Federal de São Paulo, São Paulo, Brazil, 11Instituto de Previdência dos Servidores do Estado de Minas Gerais, Belo Horizonte, Brazil, 12Faculdade de Medicina de Marilia, Marilia, Brazil, 13Santa Casa de Belo Horizonte, Belo Horizonte, Brazil

Meeting: 2015 ACR/ARHP Annual Meeting

Date of first publication: September 29, 2015

Keywords: fibromyalgia, outcomes, pain, quality of life and registry

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Session Information

Date: Sunday, November 8, 2015

Title: Fibromyalgia, Soft Tissue Disorders, Regional and Specific Clinical Pain Syndromes Poster I

Session Type: ACR Poster Session A

Session Time: 9:00AM-11:00AM

Background/Purpose: –The Brazilian registry on fibromyalgia syndrome (EPIFIBRO) included 810 patients who satisfied the American College of Rheumatology Classification Criteria for Fibromyalgia (ACR1990) at the time of diagnosis. Objectives – 1. To determine how many patients fulfill the ACR1990 and the 2010 Preliminary Diagnostic Criteria for Fibromyalgia (ACR 2010); 2. To determine if there is correlation between the impact of FM measure by the Fibromyalgia Impact Questionnaire (FIQ) and by the Polissymptomatic Distress Scale (PDS); 3. To describe data on the follow-up evaluation of the patients enrolled in the registry.

Methods: A transversal study on a multicenter cohort of Brazilian Fibromyalgia patients. The analysis included the following evolution parameters: Pain and Fatigue Analogical Numerical Scales (PNS and FNS); FIQ and PDS at entry and at the last registered evaluation. Statistical analysis included descriptive statistics and the Pearson Correlation Scale. In order to analyze the follow-up measures 30% up or down variation was defined as the minimal clinically significant difference.

Results: The mean value observed for the PNS was 8.4 ± 1.9, for FNS was 7.9 ± 2.3, for FIQ was 68.5 ± 17.1 and for PSD was 22.19 ± 5.8. In order to establish the concordance of the ACR1990 and the ACR2010 criteria 613 patients were analyzed. The fulfillment of diagnostic criteria was observed in 386 (62.9%) patients for the ACR 1990, 529 (86.2%) for the ACR 2010 and 347 patients (56.6%) for both criteria, while 39 (6.3%) only met the ACR 1990 and 185 (30.1%) only met the ACR 2010. There is a low correlation between PNS and PDS and a moderate correlation between PNS and FIQ (r = 0.359; 0.687). There was no correlation between FNS and PDS or FIQ (r = 0.073; 0.017). It was also found a moderate correlation between the FIQ and the PDS (r = 0.576). There were 314 patients with more than one evaluation. Eighty-eight patients with less than a month from the entry were excluded resulting in 226 patients with at least one follow up parameter registered (FIQ – 222; PDS – 199; both 195). Patient registry included 221 females (97.78%) and only 5 male subjects (2.21%) with a mean age of 51.58 ± 10.56 years old. The mean time of follow up was 9.11 ± 7.47 months (1–44). The mean value of the initial FIQ score was 66.10 ± 19.59 and the final value was 67.06 ± 19.13. The mean initial score of the PDS was 22.53 ± 5.57 and the final one was 19.67 ± 6.67. There were no differences on both parameters. When considering the FIQ, 37 patients (16.6%) improved, 21 worsened (9.45%), and 164 (73.87%) were stable. Concerning the PDS, 39 patients (19.59%) improved, 9 worsened (4.52%), and 151 were unchanged (75.87 %). In 146 patients there was a concordance of the FIQ and PDS results (74.87%).

Conclusion: There was a weak correlation between the ACR1990 and ACR2010. It was observed a moderate correlation between the FIQ and the PDS used to evaluate the Fibromyalgia Syndrome impact. Most Brazilian Fibromyalgia patients from EPIFIBRO Registry did not show changes in follow up parameters over time. FIQ and PSD showed good correlation in this follow up study.


Disclosure: J. E. Martinez, None; M. C. Rezende, None; E. Paiva, Pfizer Inc, 8; D. Pollak, None; M. Helfenstein Jr, None; J. R. Provenza, None; A. Ranzolin, None; R. E. Heymann, None; E. L. Ribeiro, None; M. R. Assis, None; E. J. R. Souza, None.

To cite this abstract in AMA style:

Martinez JE, Rezende MC, Paiva E, Pollak D, Helfenstein Jr M, Provenza JR, Ranzolin A, Heymann RE, Ribeiro EL, Assis MR, Souza EJR. Data from Brazilian Fibromyalgia Patients Registry (EPIFIBRO) in 2014 [abstract]. Arthritis Rheumatol. 2015; 67 (suppl 10). https://acrabstracts.org/abstract/data-from-brazilian-fibromyalgia-patients-registry-epifibro-in-2014/. Accessed .
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