ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstract Number: 2487

Comparison of QOL Evaluation Using EQ-5D-3L and EQ-5D-5L in Japanese RA Patients: A Study Using the IORRA Cohort

Kumiko Saka1, Eiichi Tanaka2, Eisuke Inoue1,3, Mai Abe1, Mika kawano1, Naohiro Sugitani1,4, Eri Sugano1, Moeko Ochiai1, Rei Yamaguchi1, Yoko Shimizu1, Naoki Sugimoto1, Katsunori Ikari1, Ayako Nakajima1,5, Atsuo Taniguchi1 and Hisashi Yamanaka6, 1Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 2Institute of Rheumatology, Tokyo Women's Medical University, Toko, Japan, 3Division of Medical Informatics, St. Marianna University School of Medicine, Kawasaki, Japan, 4Center for Rheumatic Diseases, Mie University Hospital, Tsu city, Japan, 5Center for Rheumatic Diseases, Mie University Hospital, Tsu, Japan, 6Institute of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan

Meeting: 2018 ACR/ARHP Annual Meeting

Keywords: Epidemiologic methods

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print
Session Information

Date: Tuesday, October 23, 2018

Title: Rheumatoid Arthritis – Diagnosis, Manifestations, and Outcomes Poster III: Complications of Therapy, Outcomes, and Measures

Session Type: ACR Poster Session C

Session Time: 9:00AM-11:00AM

Background/Purpose: EQ-5D-3L is frequently used for evaluation of quality of life (QOL). However, there are several problems when using EQ-5L-3L. Evaluation using EQ-5L-3L might not properly reflect the health status of patients since patients can choose from only three levels (no problems, some problems, extreme problems). Another limitation is the ceiling effect, whereby a value of 1 for QOL means “complete health”. Recently, EQ-5D-5L was developed to resolve these problems. Few reports are available which assess both methods for evaluation of QOL in the context of rheumatoid arthritis (RA). This was a comparative study of EQ-5D-3L and EQ-5D-5L in patients with RA conducted using the IORRA cohort to examine the usefulness of the EQ-5D-5L.

Methods: The subjects were Japanese RA patients who participated in the IORRA survey in October 2016. QOL evaluation using EQ-5D-3L and EQ-5D-5L were conducted at the same time, and the following analyses were cross-sectionally examined. The difference in QOL value distribution between EQ-5D-3L and EQ-5D-5L was investigated. The QOL values of EQ-5D-3L and EQ-5D-5L were compared stratified by sex, age, RA disease duration, RA disease activity, dysfunction level, and medications (steroid use, methotrexate [MTX] use and biological DMARD [bsDMARD] use). Among RA patients who evaluated themselves as “complete health” using EQ-5D-3L, the percentage of the patients which did not satisfy “complete health” was investigated.

Results: A total of 5,023 RA patients were included in this study. Baseline clinical features in this cohort were as follows: 94% women; average age of 61 years old; mean RA disease duration: 15.7 years; average DAS28: 2.6; proportions of steroid, MTX and bsDMARD use: 27.2%, 77.0%, and 23.7%, respectively. The average (SD) values of QOL using EQ-5D-3L and EQ-5D-5L were 0.83 (0.18) and 0.85 (0.16), respectively. Although among RA patients who evaluated themselves as “1”, which means “no problems” using EQ-5D-3L in the 4 dimensions (mobility, self-care, usual activities, and anxiety/depression), most of the patients also evaluated themselves as “1” using EQ-5D-5L, while among RA patients who evaluated themselves as “1” using EQ-5D-3L for “pain/discomfort”, most of the patients evaluated themselves as “2” which means “some problems” using EQ-5D-5L. The average QOL value using EQ-5D-3L stratified by each clinical feature was lower than that using EQ-5D-5L regardless of patients’ backgrounds and medications. The percentage of RA patients who evaluated themselves as “complete health” which was scored as “1” in all 5 dimensions using EQ-5D-3L and EQ-5D-5L, were 45.0% and 32.3%, respectively. Among RA patients who evaluated themselves as “complete health” using EQ-5D-3L, 28.2% were omitted from “complete health” using EQ-5D-5L. The dimension of “pain/discomfort” had the most influence on omission from “complete health”.

Conclusion: The problem of ceiling effect was improved by using EQ-5D-5L in RA patients, and was especially influenced by the dimension of “pain/discomfort”, suggesting that the EQ-5D-5L questionnaire might properly reflect the health status of RA patients.


Disclosure: K. Saka, None; E. Tanaka, ET has received lecture fees or consulting fees from Abbvie, Ayumi Pharmaceutical, Bristol Myers Squibb, Chugai Pharmaceutical, Eisai Pharmaceutical, Nippon Kayaku,, 8; E. Inoue, None; M. Abe, None; M. kawano, None; N. Sugitani, None; E. Sugano, None; M. Ochiai, None; R. Yamaguchi, None; Y. Shimizu, None; N. Sugimoto, None; K. Ikari, Astellas, AbbVie, Bristol-Meyers, Chugai, Janssen Pharmaceutical, Lilly, Takeda, and Tanabe-Mitsubishi, UCB, 8; A. Nakajima, Eisai, Bristol-Meyers, Novartis, Astellas, Noppon-Shinyaku, Pfizer, Ayumi, Daiichi-Sankyo, Taisyo-Toyama, Tanabe-Mitsubishi, Chugai, janssen, 5; A. Taniguchi, abbVie, Eisai, Jansen, Teijin, Novartis, Eli Lil, 8; H. Yamanaka, AbbVie, Eisai, Bristol-Meyers, Novartis, Behringer, Astellas, Kaken, Noppon-Shinyaku, Pfizer, UCB, Ayumi, Ono, Daoochi-Sankyo, Taisyo-Toyama, Takeda, Tanabe-Mitsubishi, Chugai, Teijin Pharma, Torii, YLbio, 9.

To cite this abstract in AMA style:

Saka K, Tanaka E, Inoue E, Abe M, kawano M, Sugitani N, Sugano E, Ochiai M, Yamaguchi R, Shimizu Y, Sugimoto N, Ikari K, Nakajima A, Taniguchi A, Yamanaka H. Comparison of QOL Evaluation Using EQ-5D-3L and EQ-5D-5L in Japanese RA Patients: A Study Using the IORRA Cohort [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 9). https://acrabstracts.org/abstract/comparison-of-qol-evaluation-using-eq-5d-3l-and-eq-5d-5l-in-japanese-ra-patients-a-study-using-the-iorra-cohort/. Accessed .
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

« Back to 2018 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/comparison-of-qol-evaluation-using-eq-5d-3l-and-eq-5d-5l-in-japanese-ra-patients-a-study-using-the-iorra-cohort/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology