ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstract Number: 2221

Association Between Serum Uric Acid/Serum Creatinine Index and Carotid Plaque in Patients with Rheumatoid Arthritis

Andrea Guajardo Aldaco1, Dionicio Galarza-Delgado2, Iris Jazmín Colunga Pedraza1, jose Ramon Azpiri-Lopez3, Jesus Cardenas-de la Garza4, Rosa Icela Arvizu-Rivera1, Maria F. Elizondo-Benitez5, Valeria Gonzalez-Gonzalez6 and Diego Salcedo-Almanza7, 1Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 2UANL Hospital Universitario, Monterrey, Nuevo León, Mexico, 3Division of Cardiology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 4Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 5Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 6Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 7Division of Radiology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico

Meeting: ACR Convergence 2024

Keywords: Atherosclerosis, Carotid Artery Disease, Subclinical Cardiovascular Disease

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print
Session Information

Date: Monday, November 18, 2024

Title: RA – Diagnosis, Manifestations, & Outcomes Poster III

Session Type: Poster Session C

Session Time: 10:30AM-12:30PM

Background/Purpose: Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease. The serum uric acid/serum creatinine ratio (SUA/SCr), which represents uric acid levels in the blood with normalized renal function, is associated with an increased cardiovascular risk. Strong associations have been demonstrated between hyperuricemia and the risk of cardiovascular disease in patients with RA. The association between SUA/SCr and the presence of carotid plaque (CP) in patients with RA has not been established. Our objective was to compare the relationship between SUA/SCr and the presence of CP in patients with RA.

Methods: A cross-sectional, observational, and descriptive study was conducted where patients aged 40 to 75 years who met the ACR/EULAR 2010 classification criteria for RA were recruited. Patients with a history of cardiovascular disease, overlap syndrome, or pregnancy were excluded. Biochemical profiles were performed. SUA/SCr was calculated using the formula SUA/SCr= Serum Uric Acid / Serum Creatinine. Carotid ultrasound was performed by a board-certified radiologist, blinded to clinical information. The presence of carotid plaque (CP), defined as a diffuse thickness of the carotid intima-media (CIMT) ≥1.2 mm or a focal thickness ≥ 0.5 mm, was assessed to calculate serum SUA and SCr levels. The distribution was evaluated using the Kolgomorov-Smirnov test. Comparisons were made with Chi-square, Fisher’s exact, Student’s T, or Mann Whitney U tests, as appropriate. A p< 0.05 was taken as statistically significant.

Results: Our study included 148 patients, mainly women (n=134, 90.5%), the mean age was 55 +/- 9.81 years. The presence of CP was reported in 30.4% of patients. The overall average for AU was 4.43 +/- 1.21 and 7.19 +/- 2.13 for SUA/SCr. Demographic characteristics can be seen in Table 1. Patients with CP had higher SUA/SCr than those without CP (7.80 +/- 2.70 vs. 6.90 +/- 1.78; p=0.040). There were no significant differences in UA levels (4.67 +/- 1.36 vs.4.30 +/- 1.12; p=0.1079).

Conclusion: In our cohort, SUA/SCr was higher in patients with CP, despite showing no significant difference in uric acid levels. However, the performance of carotid ultrasounds must be part of an integral cardiovascular evaluation.

Supporting image 1


Disclosures: A. Guajardo Aldaco: None; D. Galarza-Delgado: None; I. Colunga Pedraza: None; j. Azpiri-Lopez: None; J. Cardenas-de la Garza: None; R. Arvizu-Rivera: None; M. Elizondo-Benitez: None; V. Gonzalez-Gonzalez: None; D. Salcedo-Almanza: None.

To cite this abstract in AMA style:

Guajardo Aldaco A, Galarza-Delgado D, Colunga Pedraza I, Azpiri-Lopez j, Cardenas-de la Garza J, Arvizu-Rivera R, Elizondo-Benitez M, Gonzalez-Gonzalez V, Salcedo-Almanza D. Association Between Serum Uric Acid/Serum Creatinine Index and Carotid Plaque in Patients with Rheumatoid Arthritis [abstract]. Arthritis Rheumatol. 2024; 76 (suppl 9). https://acrabstracts.org/abstract/association-between-serum-uric-acid-serum-creatinine-index-and-carotid-plaque-in-patients-with-rheumatoid-arthritis/. Accessed .
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

« Back to ACR Convergence 2024

ACR Meeting Abstracts - https://acrabstracts.org/abstract/association-between-serum-uric-acid-serum-creatinine-index-and-carotid-plaque-in-patients-with-rheumatoid-arthritis/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology