ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstract Number: 544

Anterior Chest Wall Pain in Recent Inflammatory Back Pain. Data From the DESIR Cohort

Daniel Wendling1, Clément Prati2, Christophe Demattei3, Damien Loeuille4, P. Richette5 and Maxime Dougados6, 1Service de Rhumatologie, Minjoz University Hospital, Besancon, France, 2Service de Rhumatologie, CHU J Minjoz, Besancon, France, 3Service BESPIM, CHU, Nimes, France, 4Rheumatology, CHU Brabois, Vandoeuvre les Nancy, France, 5Centre Viggo Petersen / Service de Rhumatologie, Hôpital Lariboisière, Paris, France, 6Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France

Meeting: 2012 ACR/ARHP Annual Meeting

Keywords: Spondylarthropathy

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print
Session Information

Title: Spondylarthropathies and Psoriatic Arthritis: Clinical Aspects and Treatment

Session Type: Abstract Submissions (ACR)

Background/Purpose:

Anterior chest wall pain (ACW) may be suggestive of spondyloarthritis (SpA), but  little is known about this clinical feature in recent inflammatory back pain (IBP).

Objective. To determine the prevalence of ACW in patients with recent IBP suggestive of  SpA, and to investigate the influence of ACW on the overall features of patients presenting with recent IBP.

Methods:

The DESIR cohort is a prospective, multicenter French cohort of patients with early IBP (Calin or Berlin criteria) (>3 months and <3 years of duration) suggestive of SpA according to the investigator, including 708 patients (mean age 33.8 years, 53.8% female, 57.3% HLA B27 positive). ACW was defined by at least one episode of chest wall pain attributed to SpA by the rheumatologist, after ruling out other causes of chest pain. Data on the baseline demographic characteristics, functional status and quality of life, imaging features (standard X-Rays, MRI, Ultrasounds), BMD, and blood tests were compared in patients with and without ACW. Both the date of the first symptom of IBP and the symptoms of ACW were recorded, as well as the date of the visit. Factors associated with ACW were identified both by uni and multivariate analysis (logistic regression).

Results:

The prevalence of ACW in the DESIR cohort was 44.6 % [95%CI 40.9-48.3] (n=316/708 patients). ACW occurred after the first symptoms of IBP in 62 %, before in 14 %, and simultaneously (±1month) in 24 % of the cases. Localization was diffuse in 41% of the positive cases, sterno costal (35%), manubrio sternal (29%) or sterno clavicular (26%). Presence of ACW was significantly associated in univariate analysis with pain in cervical and thoracic spine, buttock, peripheral arthritis and enthesitis, fulfilment of ASAS and ESSG criteria, associated reactive arthritis and SAPHO, increased BASDAI, ASDAS, BASFI, BASG, SF-36, BASMI, articular index, increased CRP, radiographic sacro iliac involvement and reduced BMD. ACW was not associated with HLA-B27, uveitis, psoriasis, smoking, age and MRI findings. A stepwise multivariate analysis found an association between ACW and (Table) : the enthesitis score, involvement of the thoracic spine, diagnosis of ankylosing spondylitis and radiographic abnormality of the sacro iliac joints.

 

ACW  (n=316)

No ACW  (n=392)

Adjusted OR

p-value

Global enthesitis score

(0-13)

 

3,65 ± 3,57

 

1,91 ± 2,53

 

1.213 [1.148-1.282]

For an increase of 1 unit

<0.0001

Involvement of the thoracic spine (pain)

Yes versus no

212 (67%)

192 (49%)

2.201 [1.582-3.062]

<0.0001

Diagnosis before inclusion : Ankylosing Spondylitis

Yes versus No

150 (47%)

148 (38%)

1.642 [1.176-2.293]

0.0036

Radiographic sacro iliac score

0 : normal

1 : doubtful

2 : established

3 : fusion

142 (46%)

81 (26%)

76 (24%)

12 (3.90%)

209 (55%)

75 (20%)

96 (25%)

3 (0.78%)

1.692 [1.128-2.538]

1.295 [0.863-1.943]

7.299 [1.938-27.48]

0.0109

0.2121

0.0033

Conclusion:

In recent IBP suggestive of SpA, presence of ACW is associated with enthesitis, thoracic spine involvement, radiographic sacro iliitis and the diagnosis of ankylosing spondylitis. Since there are no differences in symptoms duration between ACW positive and ACW negative patients, ACW could be interpreted as an independent  diagnosis feature for ankylosing spondylitis.


Disclosure:

D. Wendling,
None;

C. Prati,
None;

C. Demattei,
None;

D. Loeuille,
None;

P. Richette,
None;

M. Dougados,
None.

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

« Back to 2012 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/anterior-chest-wall-pain-in-recent-inflammatory-back-pain-data-from-the-desir-cohort/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology