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Abstract Number: 796

African American Adults Less Willing to Undergo Joint Replacement Surgery: The Multicenter Osteoarthritis Study

Julie J. Keysor1, Huan J. Chang2, Tianzhong Yang3, Cora E. Lewis4, James Torner5, Michael C. Nevitt6 and David T. Felson7, 1Physical Therapy, Boston University Sargent College, Boston, MA, 2The Journal of the American Medical Association, Chicago, IL, 3Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 4Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, 5Epidemiology, University of Iowa, Iowa City, Iowa City, IA, 6Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 7Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA

Meeting: 2012 ACR/ARHP Annual Meeting

Keywords: African-Americans and total joint replacement

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Session Information

Title: Osteoarthritis

Session Type: Abstract Submissions (ARHP)

Background/Purpose: “Willingness” to undergo joint replacement surgery (JRS) is predictive of subsequent JRS among community-dwelling older adults and could, at least in part, explain the noted ethnic disparity in JRS utilization. Differences between African Americans and whites in JRS “willingness” have not been explored nor have other factors that affect willingness.

Methods: The Multicenter Osteoarthritis Study (MOST) is a prospective community-based study of 3026 adults 50-79 years old with or at risk of developing symptomatic knee or hip osteoarthritis (OA). Participants were from Birmingham, Alabama and Iowa City, Iowa. “Willingness to undergo JRS” was ascertained among participants at the 60-month visit as follows: “based on your understanding of the risks and benefits of hip and knee joint replacement surgery and if your symptoms were severe enough, would you be willing to have joint replacement surgery for your hips or knees?” Responses were coded “willing” or “not willing”. The following risk factors for willingness were assessed at the same time: age, gender, education, and race (African American and white); living situation (alone vs. with someone), comorbidity, OA radiographic severity, pain severity, function, depressive symptoms, pain catastrophizing, and study site. We excluded participants who already had a knee or hip replacement (N=438). We used logistic regression to examine the association of ethnicity with JRS willingness after adjusting for covariates.

 

Results: 1808 subjects who participated in the 60 month exam were included. The mean age of the sample was 67.7 (SD 7.8); 60% were female, 14% were African American, 27% did not have education beyond high school;18.4% lived alone; 11% had high depressive symptoms; 25% reported high pain catastrophizing.  In crude and adjusted models, African Americans were significantly less likely to report being “willing” to undergo JRS (Table 1).  Willingness declined with age and those from Alabama were less willing than subjects from Iowa. Men and persons with depressive symptoms tended to be less willing (p=0.06). Knee OA severity, pain severity, function, pain catastrophizing, andr living situation were not associated with willingness.

Conclusion: “Willingness” may explain some of the disparities in TKR utilization between African Americans and whites. Older and depressed persons and persons from certain locale’s may also be less willing to have TKRs and THRs. Longitudinal studies are needed to establish causality.

Table 1: Risk  Factors Associated with “Willingness” to Have a Total Joint Replacement (Odds Ratios below one signify decreased willingness to undergo THR or TKR; Bold highlight indicates p=0.05 significance)

 

Unadjusted

Adjusted

Variable (range)

Odds Ratio

95% Confidence Interval

Odds Ratio

95% Confidence Interval

Race (African American vs. White)

0.27

0.20, 0.35

0.32

0.23,0.45

Age 50-59 years

 

 

1

referent

Age  60-69 years

 

 

0.81

0.59, 1.11

Age 70-79 years

 

 

0.50

0.36, 0.69

Age  80+ years

 

 

0.37

0.22, 0.60

Alabama site (referent Iowa)

 

 

0.68

0.53, 0.89

Male (referent female)

 

 

1.3*

1.00, 1.64*

Lives alone (referent lives with someone)

 

 

1.0

0.75, 1.34

OA Severity

 

 

0.93

0.85, 1.04

Education (referent: some high school)

 

 

1.14

0.63, 2.06

Comorbidity

 

 

1.04

0.95, 1.14

Pain Severity (1-10)

 

 

0.98

0.92, 1.05

WOMAC function (lowest tertile: best)

 

 

1.0

referent

WOMAC function (middle tertile)

 

 

1.16

0.85, 1.58

WOMAC function (highest tertile: worst)

 

 

1.10

0.74, 1.62

Depressive symptoms (referent no symptoms)

 

 

0.71*

0.50, 1.02*

Pain catastrophizing

 

 

0.81

0.62, 1.07

* Approached significance at p=.06

 


Disclosure:

J. J. Keysor,
None;

H. J. Chang,
None;

T. Yang,
None;

C. E. Lewis,
None;

J. Torner,
None;

M. C. Nevitt,
None;

D. T. Felson,
None.

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