ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 51

High Incidence of Non-Vertebral Osteoporotic Fracture and Hip Fracture in Brazilian Low-Income Community-Dwelling Elderly: A Population-Based Prospective Cohort Analysis from the São Paulo Ageing & Health (SPAH) Study

Diogo S. Domiciano1, Luana G. Machado2, Jaqueline B. Lopes2, Camille P. Figueiredo2, Valéria Caparbo2, Liliam Takayama2, Ricardo Oliveira3, Paulo R Menezes4 and Rosa M. R. Pereira5, 1Rheumatology, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil, 2Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 3RDO Diagnósticos Médicos, São Paulo, Brazil, 4Preventive Medicine, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil, 5Reumatologia, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil

Meeting: 2014 ACR/ARHP Annual Meeting

Keywords: , ,

Session Information

Title: Epidemiology and Public Health: Osteoporosis, Non-Inflammatory Arthritis and More

Session Type: Abstract Submissions (ACR)

Background/Purpose: There is considerable variability in the incidence of hip fracture among countries, even among different geographical areas within the same country. In Brazil, population differences in occurrence of hip fracture are probably related to the huge size of the country, the substantial ethnical miscegenation and distinct lifestyle habits within the Brazilian territory. Longitudinal studies on incidence of hip fracture in the Brazilian population are scarce and the results are hampererd by incomplete capture of cases and short follow-up time. Moreover, there is no prospective study on incidence of non-vertebral fractures beyond the hip. Thus, our aim was to describe the incidence of hip and non-vertebral fracture in elderly community from a prospective population-based study.

Methods: Incidence of hip and non-vertebral fracture were determined in 707 women and men from community, aged 65 years or older. Specific questionnaire (clinical and anthropometric data), including personal history of fragility fracture in non-vertebral osteoporotic sites (hip, humerus, wrist, rib) was performed at baseline and after an average of 4.3 years. All incident fractures during the study period were confirmed by radiograph of the affected site.

Results: 449 women (mean age 72.9 ± 4.8 years) and 258 men (mean age 72.3 ± 4.7 years) were included in the study. The age-adjusted incidence of non-vertebral fracture was 1710/100.000 person-years in women and 630/100.000 person-years in men (female/male ratio: 2.6). The age-adjusted incidence of hip fracture was 420/100.000 person-years in women and 90/100.000 person-years in men (female/male ratio: 4.7). The incidence increases with age, particularly in women.

Conclusion: The incidence of non-vertebral osteoporotic fracture in the Brazilian elderly population was high, especially among women. Concerning hip fracture, these results emphasize that the incidence in the southern and southeastern regions of the country seems to be higher than the rates in the northern/northeastern population. Furthermore, our results reinforce the notion that the incidence of hip fracture in Brazilian older adults, particularly in women, is higher than in other Latin American populations, except Argentina.

Disclosure:

D. S. Domiciano,
None;

L. G. Machado,
None;

J. B. Lopes,
None;

C. P. Figueiredo,
None;

V. Caparbo,
None;

L. Takayama,
None;

R. Oliveira,
None;

P. R. Menezes,
None;

R. M. R. Pereira,
None.

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