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Abstract Number: 2026

Are Adult Trajectories of Weight over a Lifetime Linked to Foot Problems Years Later?

Alyssa B. Dufour1, Elena Losina2, Hylton B. Menz3, Michael P. Lavalley4 and Marian T. Hannan5, 1Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School & Beth Israel Deaconess Medical Center, Boston, MA, 2Orthopaedics, Brigham & Women's Hospital, Boston, MA, 3Musculoskeletal Research Centre, La Trobe University, Bundoora, VIC, Australia, 4Biostatistics, Boston University School of Public Health, Boston, MA, 5Institute for Aging Research, Hebrew SL & Harvard Med School, Boston, MA

Meeting: 2016 ACR/ARHP Annual Meeting

Date of first publication: September 28, 2016

Keywords: body mass, Epidemiologic methods, foot disorders, longitudinal studies and obesity

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Session Information

Date: Monday, November 14, 2016

Title: ACR/ARHP Combined Abstract Session: Epidemiology and Pubic Health

Session Type: ACR Concurrent Abstract Session

Session Time: 4:30PM-6:00PM

Background/Purpose: Obesity and foot problems are common in older adults and associated with many negative health outcomes. Better understanding of the consequences of patterns of weight change may lead to better prediction and dealing with foot pain and foot disorders.  This study identified longitudinal trajectories of weight in a population-based study and examined the association of these groups with current foot problems.

Methods: We used 28 measures of weight over 57 years to identify trajectories of weight in 2445 members of the Framingham Foot Study using k-means longitudinal cluster analysis.  Foot examinations (2002-2008) recorded presence of foot pain, hallux valgus, claw toes, hammer toes and overlapping toes on each foot.  Associations between weight group membership and foot problems at time of foot exam, adjusted for age and sex, were examined using logistic regression with generalized estimating equation correction for two feet per subject.  The reference group used for analysis was the group with the lowest weight trajectory (“E”).

Results:   We found 5 trajectories of weight, representing relatively constant patterns over time, with weight increasing from groups E to A.  Those in group “E” were more likely to be older, while the youngest were in group “A” group (Table 1). “E” had the lowest prevalence of foot pain (14%) while group “A” had the highest (22%).  Similarly, group “A” had the lowest prevalence of hallux valgus, while group “E” had the highest (36%).  Compared to group “E”, other groups were more likely to have foot pain (ORs 1.57-3.50, Table 2) and less likely to have hallux valgus (ORs 0.73-0.99).  For claw toes, all but one group were more likely to have claw toes compared to group “E”.  Groups “A” and “D” were more likely to have hammer toes (ORs 2.40 and 1.35, respectively) compared to group “E”.  We found no associations between overlapping toes and group membership.

Conclusion:   Trajectories with higher weight over a lifetime had increased odds of foot pain and claw toes, and decreased odds of hallux valgus later in life.  These results provide evidence that having lower weight over one’s lifetime can reduce the likelihood of foot problems later in life.   

Table 1. Participant characteristics by weight trajectory group in members of the Framingham Foot Stud (2002-2008).
 

A

N=201/

402 feet

B

N=644/

1288 feet

C

N=617/

1233 feet

D

N=506/

1011 feet

E

N=477/

954 feet

Age (years)

63 ± 9.0

69 ± 11.2

68 ± 10.5

66 ± 9.7

71 ± 11.9

Body mass index (kg/m2)

37 ± 6.3

27 ± 3.3

29 ± 4.0

31 ± 4.3

23 ± 2.9

Female

76 (19%)

1036 (80%)

478 (39%)

230 (23%)

918 (96%)

Foot pain

88 (22%)

240 (19%)

222 (18%)

186 (18%)

135 (14%)

Hallux Valgus

57 (14%)

408 (32%)

267 (22%)

169 (17%)

341 (36%)

Claw Toes

9 (2%)

29 (2%)

29 (2%)

24 (2%)

18 (2%)

Hammer toes

89 (22%)

246 (19%)

197 (16%)

165 (16%)

174 (18%)

Overlapping toes

14 (3%)

99 (8%)

73 (6%)

48 (5%)

90 (9%)

 

Table 2. Association between weight trajectory group membership and foot problems in members of the Framingham Foot Study (2002-2008), adjusted for age and sex. *p<0.05

A vs. E

B vs. E

C vs. E

D vs. E

Foot pain

3.5 (2.49, 4.9)*

1.57 (1.25, 1.98)*

2.16 (1.68, 2.77)*

2.63 (2.00, 3.47)*

Hallux Valgus

0.72 (0.51, 1.02)

0.99 (0.82, 1.18)

0.86 (0.7, 1.06)

0.77 (0.61, 0.99)*

Claw toes

3.97 (1.57, 10)*

1.52 (0.83, 2.79)

2.24 (1.17, 4.29)*

3.1 (1.51, 6.38)*

Hammer toes

2.4 (1.71, 3.38)*

1.2 (0.96, 1.5)

1.12 (0.87, 1.45)

1.35 (1.02, 1.79)*

Overlapping toes

0.78 (0.41, 1.48)

0.93 (0.68, 1.27)

0.87 (0.6, 1.25)

0.85 (0.55, 1.32)

 


Disclosure: A. B. Dufour, None; E. Losina, None; H. B. Menz, None; M. P. Lavalley, None; M. T. Hannan, None.

To cite this abstract in AMA style:

Dufour AB, Losina E, Menz HB, Lavalley MP, Hannan MT. Are Adult Trajectories of Weight over a Lifetime Linked to Foot Problems Years Later? [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/are-adult-trajectories-of-weight-over-a-lifetime-linked-to-foot-problems-years-later/. Accessed .
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