Background/Purpose:

For the past decades, the rash at the Bacillus Calmettee-Guérin (BCG) inoculation sites has been recognized as a useful diagnostic clue in Kawasaki disease (KD). However, the detailed characterization of the BCG reaction and its correlation with systemic involvements in KD has not been evaluated. We sought to characterize the BCG reaction in KD and correlate the grade of BCG reaction with the systemic involvements in patients with KD.

Methods: History taking, laboratory examination, physical examination, and dermatoscopic examination were performed in 10 patients diagnosed with KD

Results:

We identified four dermoscopic patterns: atypical targets (targetoid) pattern in 3 patients; typical target pattern in 2 patients; faint homogenous erythema in 3 patients; a more or less evident white patch, in the central area in 2 patients. Elevated blood level of liver enzymes is associated with the presence of typical target and atypical target pattern in patients.

Conclusion:

The dermoscopic patterns may help dermatologists and pediatrician to consolidate the diagnosis of Kawasaki disease. The target or targetoid pattern observed under dermoscope is a useful biomarker for systemic involvements in patients with KD.

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ACR Meeting Abstracts - https://acrabstracts.org/abstract/target-and-targetoid-reactions-at-bacillus-calmettee-guerin-inoculation-site-revealed-by-dermatoscopy-correlate-with-systemic-involvements-in-patients-with-kawasaki-disease/