Background/Purpose: Fibromyalgia syndrome (FMS) is characterized by widespread pain, fatigue, memory problems. The syndrome is present in about %2-8 of general population. However, knowledge about this topic in specific populations is limited. Our aim was to evaluate FMS in patients undergoing peritoneal dialysis, and association between clinical and laboratory parameters.

Methods: Twenty-six patients (7 females and 19 males with mean age of 53±15,9 years) receiving peritoneal dialysis were enrolled in this study. The control group compromised 25 healthy adults (16 females and 9 males with mean age of 41±12,8 years). Diagnosis of fibromyalgia was performed according to the 1990 American College of Rheumatology (ACR) and 2011 modification of the ACR preliminary diagnostic criteria. Age, sex, causes of renal failure, dialysis duration, the level of parathyroid hormone, renal function tests and electrolites were recorded. Mann-Whitney U and chi-square test were performed as statistical analysis and p<0.05 was accepted as statistically significant.

Results: The etiology of renal failure was diabetes mellitus in 3 patients (11,5%), hypertension in 10 (38,5%), glomerulonephritis in 4 (15,4%), idiopathic in 5 (19,2%), polycystic kidney disease in 1 (3,8%), nephrolithiasis in 2 (7,7%), and pyelonephritis in 1 (3,8%). The mean dialysis duration was 50,42±35,19 months. One (3,84%) patients receiving peritoneal dialysis and one of 25 control subjects were diagnosed with fibromyalgia, respectively. The mean age was 53±15,9 years in dialysis group, and 41±12,8 years in control group. All of FMS was female. There was significant difference for renal function tests and electrolites between both groups (p<0,001). Ionized calcium and phosphorus were higher in the FMS group than in the control group (p=0.056, p=0.596, respectively). There was no association between FMS and secondary hyperparathyroidism. The level of plasma parathyroid hormone in FMS patients was significantly lower than other patients. 

Conclusion: There was similar prevalence for fibromyalgia between patients on peritoneal dialysis and healty group. It may be associated with actively participate in treatment, less stress factors, and better preservation of renal functions.

« Back to 2015 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/evaluation-of-fibromyalgia-syndrome-in-patients-undergoing-peritoneal-dialysis/