ACR Meeting Abstracts

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  • Abstract Number: 0530 • ACR Convergence 2022

    Abatacept Significantly Reduces Subclinical Inflammation During Treatment (6 Months), This Persists After Discontinuation (12 Months), Resulting in a Delay in the Clinical Development of RA in Patients at Risk of RA (The ARIAA Study)

    Juergen Rech1, Arnd Kleyer2, Mikkel Østergaard3, Melanie Hagen2, Larissa Valor Mendez2, Koray Tascilar2, Gerhard Kroenke2, Verena Schönau2, David Simon2, stefan Kleinert4, Xenofon Baraliakos5, Juergen Braun6, Axel Hueber7, Martin Fleck8, Andrea Rubbert-Roth9, Frank Behrens10, Martin Feuchtenberger11, M. Zaenker12, Reinhard Voll13, Cornelia Glaser14, Mária Filková15, Eugen Feist16, Gerd Burmester17, Kirsten Karberg18, Johannes Strunk19, Juan Canete20, Ladislav Šenolt15, Esperanza Naredo21 and Georg Schett22, 1University Clinic Erlangen, Erlangen, Germany, 2Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 3Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 4Praxisgemeinschaft Rheumatologie - Nephrologie (PGRN), Erlangen, Germany, 5Ruhr University Bochum, Department of Rheumatology, Bochum, Germany; Rheumazentrum Ruhrgebiet, Rheumazentrum Ruhrgebiet, Herne, Germany, 6Rheumazentrum Ruhrgebiet, Herne, Germany, 7Klinikum Nuernberg Nord, Abteilung fuer Rheumatologie, Nuernberg, Germany, 8Asklepios Klinikum Bad Abbach, Klinik und Poliklinik für Rheumatologie/ Klin. Immunologie, Bad Abbach, Germany, 9Division of Rheumatology, Cantonal Clinic St Gallen, St.Gallen, Switzerland, 10Division of Rheumatology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany; Fraunhofer Institute for Translational Medicine & Pharmacology ITMP, Frankfurt, 11MED | BAYERN OST GmbH, Fachbereich Rheumatologie, Burghausen, Germany, 12Immanuel Klinikum Bernau , Herzzentrum Brandenburg, Abteilung Innere Medizin, Bernau, Germany, 13Universitätsklinikum Freiburg, Klinik für Rheumatologie und Klinische Immunologie, Freiburg im Breisgau, Germany, 14Universitätsklinikum Freiburg, Klinik für Rheumatologie und Klinische Immunologie, Freiburg, Germany, 15Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, 16Helios Clinic Vogelsang-Gommern, cooperation partner of the Otto von Guericke University Magdeburg, Magdeburg, Germany, 17Charité University Medicine Berlin, Berlin, Germany, 18Praxis für Rheumatologie und Innere Medizin, Rheumatologie, Berlin, Germany, 19Krankenhaus Porz am Rhein GmbH, Rheumaklinik, Köln (Porz), Germany, Koeln, Germany, 20Unidad de Artritis Hospital Clinic, Barcelona, Spain, 21Hospital General Universitario Gregorio Marañón and Complutense University, Madrid, Spain, 22Universitätsklinikum Erlangen, Erlangen, Germany

    Background/Purpose: Development of the clinical phase of rheumatoid arthritis (RA) is preceded by an autoimmune phase, characterized by the presence of anti-citrullinated protein antibodies (ACPA),…
  • Abstract Number: 0530 • ACR Convergence 2021

    Dysregulation of IGFI/IGF1R Pathway and IGF1R+3179A/G Polymorphism in Pathogenesis of Sjögren’s Syndrome

    Charalampos Skarlis1, Adrianos Nezos2, Nikolaos Marketos1, Asimina Papanikolaou3, Athanasios Tzioufas4, Michael Koutsilieris1, Haralampos Moutsopoulos5 and Clio Mavragani1, 1National and Kapodistrian University of Athens, Athens, Greece, 2National & Kapodistrian University of Athens, Athens, Greece, 3Department of Haemopathology, "Evangelismos" Hospital, Athens, Greece, Athens, Greece, 4Department of Pathophysiology, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece, 5Athens Academy of Athens, Chair Medical Sciences/Immunology, Athens, Greece

    Background/Purpose: Sjӧgren’s syndrome (SS) is an autoimmune exocrinopathy characterized by chronic salivary and lacrimal gland dysfunction. Alterations of Insulin-like growth factor (IGF) pathway has been…
  • Abstract Number: 0530 • ACR Convergence 2020

    Pediatric APS: Clinical Features, Therapeutic Interventions, and Damage in a Series of 22 Cases

    Jacqueline Madison1, Kelsey Gockman1 and Jason Knight2, 1University of Michigan, Ann Arbor, 2Division of Rheumatology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Pediatric antiphospholipid syndrome (APS) is a thromboinflammatory disease classically defined by the presence of circulating antiphospholipid antibodies and either thrombotic events or pregnancy morbidity.…
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ACR Pediatric Rheumatology Symposium 2020

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