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Abstract Number: 0311 • ACR Convergence 2025
Time series analysis of continuous accelerometry data to determine the impact of symptomatic multiple joint osteoarthritis (MJOA) in the naturally occurring canine model
Elizabeth Kawecki-Wright¹, Liubov Arbeeva², Christina Stevens¹, Masataka Enomoto¹, Amanda Nelson³, Margaret Gruen¹ and Duncan Lascelles¹, ¹North Carolina State University, RALEIGH, NC, ²University of North Carolina, Chapel Hill, Carrboro, NC, ³University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: Pet dogs are a promising translational model for naturally occurring multiple joint osteoarthritis (MJOA). We characterized the impact of symptomatic (sx) MJOA, over the…
Abstract Number: 0311 • ACR Convergence 2024
Investigation of Sarcoidosis-associated Neuropathy: Challenges with Diagnosis of Small Fiber Neuropathy
Kristen Caldwell¹, Sindhuja Koppu¹, Kelly Gwathmey¹, Aamer Syed¹, Jordana Kron¹, Thomas Iden¹ and Huzaefah Syed², ¹Virginia Commonwealth University, Richmond, VA, ²Virginia Commonwealth University Medical Center, Richmond, VA
Background/Purpose: Small fiber neuropathy (SFN) is an underrecognized complication of sarcoidosis which can significantly impair individuals’ physical functioning and quality of life. Diagnosis includes both…
Abstract Number: 0311 • ACR Convergence 2023
Heterogeneity and Natural History of Medial Fixed Joint Space Width in Healthy Knees Among Women and Men: Data from Three Large Cohort Studies
Kent Kwoh¹, Erin Ashbeck², Edward Bedrick¹, Yvonne Golightly³, Zong-Ming Li¹, Jean liew⁴, Amanda Nelson⁵, Tuhina Neogi⁶, Xiaoxiao Sun¹ and Jeffrey Duryea⁷, ¹University of Arizona, Tucson, AZ, ²University of Arizona Arthritis Center, Tucson, AZ, ³University of Nebraska Medical Center, Omaha, NE, ⁴Boston University, Boston, MA, ⁵University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁶Boston University School of Medicine, Boston, MA, ⁷Brigham and Women's Hospital, Boston, MA
Background/Purpose: Radiographic joint space width (JSW) is commonly used to assess structural progression in randomized controlled trials and observational studies of knee osteoarthritis (KOA). No…
Abstract Number: 0311 • ACR Convergence 2022
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Zunsemetinib, an Investigational Oral MK2 Inhibitor, at 80 Mg and 120 Mg Twice Daily Dose Levels in Healthy Subjects
Ajay Aggarwal¹, David Burt², Laura Connelly², Joseph Monahan² and Jessea Lu², ¹Aclaris Therapeutics, Wellesley, MA, ²Aclaris Therapeutics, Inc., Wayne, PA
Background/Purpose: Zunsemetinib is an orally available potent and selective small molecule inhibitor of the p38α MAPK/MK2 signaling axis. Aclaris Therapeutics, Inc. is developing zunsemetinib for…
Abstract Number: 0311 • ACR Convergence 2021
Ultra High‐frequency Ultrasound (UHFUS) of Labial Glands in Primary Sjögren’s Syndrome: Serological and Histological Correlations
Giovanni Fulvio¹, Francesco Ferro¹, Rossana Izzetti², Gianmaria Governato¹, Silvia Fonzetti¹, Gaetano La Rocca¹, Valentina Donati³, Davide Caramella⁴, Marta Mosca⁵ and Chiara Baldini⁶, ¹University of Pisa, Rheumatology Unit, Pisa, Italy, ²University of Pisa, Unit of Dentistry and Oral Surgery, Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, Pisa, Italy, ³AOUP, Unit of Pathological Anatomy, Pisa, Italy, ⁴University of Pisa, 3Diagnostic and Interventional Radiology, Department of Translational Research and of New Technologies in Medicine and Surgery, Pisa, Italy, ⁵Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, ⁶University of Pisa, Pisa, Italy
Background/Purpose: Last‐generation ultra high‐frequency ultrasound (UHFUS) transducers are highly sensitive tools potentially able to open new avenues for the identification of imaging biomarkers. Recently UHFUS…
Abstract Number: 0311 • ACR Convergence 2020
The Link Between Joints and Entheses in Psoriatic Arthritis: An Ultrasound Study Supporting the Synovio-entheseal Complex Theory
Gizem Ayan¹, Ilaria Tinazzi², Sibel Bakirci³, Ummugulsum Gazel⁴, Dilek Solmaz⁵, Umut Kalyoncu⁶ and Sibel Aydin⁷, ¹University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA, Ottawa Hospital Research Institute, OTTAWA, ON, Canada, ²Sacro Cuore Don Calabria Hospital, Unit of Rheumatology, Negrar-Verona, VR, ITALY, Verona, Italy, ³Antalya Research and Training Hospital, Antalya, TURKEY; University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA, Antalya, Turkey, ⁴University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA; The Ottawa Hospital Research Institute, Ottawa, ON, CANADA, ottawa, Canada, ⁵Izmir Katip Celebi University, Department of Internal Medicine, Division of Rheumatology, Izmir, TURKEY, Izmir, Turkey, ⁶Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ⁷University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA; The Ottawa Hospital Research Institute, Ottawa, ON, CANADA, Ottawa, ON, Canada
Background/Purpose: The aim of this study is to explore the link between the severity of the joint and entheses involvement in psoriatic arthritis (PsA) using…

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