Session » Systemic Sclerosis, Fibrosing Syndromes and Raynaud's - Pathogenesis, Animal Models and Genetics
-
Abstract Number: 744
Integrin Inhibitor Modulates Pulmonary Fibrosis in the Reactive Oxygen Species Murine Model of Systemic Sclerosis
-
Abstract Number: 745
Genetic Susceptibility Loci of Idiopathic Interstitial Pneumonitis Do Not Represent Risk for Systemic Sclerosis
-
Abstract Number: 746
Elevated Pentraxin 3 in Patients with Systemic Sclerosis: Associations with Vascular Manifestations and Defective Vasculogenesis
-
Abstract Number: 747
Systemic Sclerosis Patients with Antitopoisomerase Antibodies Showed Significant Association with CCR6 Polymorphisms
-
Abstract Number: 748
Increased Expression of Chemerin in Endothelial Cells Due to Fli1 Deficiency May Contribute to the Development of Digital Ulcers in Systemic Sclerosis
-
Abstract Number: 749
Progranulin Overproduction Due to Fli1 Deficiency Contributes to the Resistance of Dermal Fibroblasts to Tumor Necrosis Factor a in Systemic Sclerosis
-
Abstract Number: 750
Molecular Characterization of Systemic Sclerosis Esophageal Pathology Identifies Inflammatory and Proliferative Signatures with Few Fibrotic Markers
-
Abstract Number: 751
Dissecting the Heterogeneity of Skin Gene Expression Patterns in Systemic Sclerosis
-
Abstract Number: 752
Potential Roles of Toll-like Receptor 4 in the Murine Models of Systemic Sclerosis
-
Abstract Number: 753
Identification of IL12RB1 As a Novel Systemic Sclerosis Susceptibility Locus
-
Abstract Number: 754
The Global miRNA Whole Blood Profile in Systemic Sclerosis and Its Correlation with Serum Cytokine Levels
-
Abstract Number: 755
Increased Degradation of BMPR2 in a TGFβ Dependent Transgenic Mouse Model of Scleroderma with Susceptibility to Pulmonary Arterial Hypertension
-
Abstract Number: 756
Nucleosome, a Basic Repeating Unit of Chromatin, in Patients with Systemic Sclerosis: Possible Association with Immunological Abnormalities Via Abnormal Activation of T and B Cells
-
Abstract Number: 757
Distinctive Patterns of Telomere Shortening and Apoptosis in Limited and Diffuse cutaneous Systemic Sclerosis
-
Abstract Number: 758
Assessment of mRNA Gene Expression Based on Forearm Skin Score in Systemic Sclerosis Patients
-
Abstract Number: 759
The Anti-Fibrotic Effect of Endostatin-Derived Peptide Is Mediated By Urokinase
-
Abstract Number: 760
Use of Multiplex Cytokine Analysis of Dermal Blister Fluid to Assess Local Inflammatory and Immune Activity in Systemic Sclerosis
-
Abstract Number: 761
Specific Autoantibody Profiles and Disease Subgroups Correlate with Circulating Micro-RNA in Systemic Sclerosis
-
Abstract Number: 762
IQGAP1 Enhances Contractility of Scleroderma Lung Fibroblasts and Promotes Bleomycin-Induced Pulmonary Fibrosis
-
Abstract Number: 763
Caveolin-1 and Peroxisome Proliferator-Activated Receptor Gamma Co-Regulate the Differentiation of Monocytes to Adipocytes and Myofibroblasts in Vivo and in Vitro
-
Abstract Number: 764
ERG and FLI1 in Systemic Sclerosis-Associated Pulmonary Complications
-
Abstract Number: 765
Gene-Gene Interaction of IRF5 and BLK Polymorphisms in US and Spanish Cohorts of Systemic Sclerosis (SSc)
-
Abstract Number: 766
Endothelial Fli1 Deficiency Delays Wound Healing Due to Impaired Anastomosis of Newly Formed Vessels – a Possible Mechanism of Refractory Skin Ulcers in Systemic Sclerosis
-
Abstract Number: 767
The Impact of Plasmacytoid Dendiritc Cells (pDCs) on Fibrosis in bleomycin–induced Murine Model of Systemic Sclerosis (SSc)
-
Abstract Number: 768
Transforming Growth Factor Beta Induces anti Angio and Vasculo-Genesis Phenotype in Dermal Fibroblasts through Secretion of Pigment Epithelium Derived Factor
-
Abstract Number: 769
Anti-Fibrotic Effects of an Investigational Drug: Bis-Oxetanyl Sulfoxide
-
Abstract Number: 770
Detection of Proteins in Lung Tissues of Patients with Systemic Sclerosis Using Tissue Microarrays
-
Abstract Number: 772
RNA-Seq and Mir-Seq Analysis of SSc Skin Across Intrinsic Gene Expression Subsets Shows Differential Expression of Non-Coding RNAs Regulating SSc Gene Expression
-
Abstract Number: 1704
CXCL4 Promotes Fibrosis By Increasing Expression of Extracellular Matrix Modifying Factors and By Facilitating Epithelial/Endothelial Mesenchymal Transition
-
Abstract Number: 1705
The Lectin Pathway of Complement – a Potential Role in the Pathogenesis and Disease Manifestations of Systemic Sclerosis
-
Abstract Number: 1706
Prevention of SU5416-Induced Pulmonary Hypertension in a TGFβ Dependent Genetic Mouse Model of Scleroderma Using the Endothelin Receptor Antagonist Macitentan
-
Abstract Number: 1707
High Oxidative Stress in Fibrotic and Non-Fibrotic Skin of Patients with Systemic Sclerosis
-
Abstract Number: 1708
The Pathogenic Role of Immune Complexes Containing Scleroderma-Specific Autoantibodies in the Inductor Phase of the Disease
-
Abstract Number: 1710
Endothelin-1 Is a Downstream Mediator of Profibrotic Effects by Transforming Growth Factor-β1 in Systemic Sclerosis Skin Fibroblasts
-
Abstract Number: 1711
The Relationship Between Vascular Biomarkers and Disease Characteristics in Systemic Sclerosis: Elevated MCP-1 Is Associated with Predominantly Fibrotic Manifestations
-
Abstract Number: 1712
Monocytic Angiotensin and Endothelin Receptor Imbalance Determines Secretion of the Profibrotic Chemokine Ligand CCL18
-
Abstract Number: 1713
Increased Number of CD206+cells in Peripheral Blood and Skin of Systemic Sclerosis Patients
-
Abstract Number: 1714
IL-6 Trans-Signalling Activates M2 Macrophage Polarisation and Mediates Fibrotic Response in Scleroderma
-
Abstract Number: 1715
Serum Levels of CD163/Tweak Predict Risk of Digital Ulcers in Patients with Systemic Sclerosis
-
Abstract Number: 1716
MHC Class I and Class II Genes Influence Systemic Sclerosis Susceptibility, Clinical Presentation and Autoantibody Profile in a Mexican Admixed Population
-
Abstract Number: 1717
Endothelial to Mesenchymal Transition Contributes to the Development of Pulmonary Vasculopathy in Systemic Sclerosis PAH
-
Abstract Number: 1718
B Cell Subsets Homeostasis and Functional Properties Are Altered in a Murine Model of Systemic Sclerosis
-
Abstract Number: 1719
Periostin May Promote Productin of Extracellular Matrix By Modulating TGF-β Signaling in Human Skin Fibroblasts
-
Abstract Number: 1720
GATA6 Deficiency Activates UPR Pathways in Endothelial Cells during the Development of Pulmonary Arterial Hypertension
-
Abstract Number: 1721
Investigating the SCF/c-Kit Pathway in Scleroderma Fibrosis
-
Abstract Number: 1722
TLR4 and TLR7 Are Required for Gadolinium Based Contrast Agent Induction of Dermal and Pulmonary Fibrosis in an Adenine-Induced Model of Chronic Renal Failure
-
Abstract Number: 1723
Identification of the Microbiome As a Potential Trigger of Systemic Sclerosis By Metagenomic RNA-Sequencing of Skin Biopsies
-
Abstract Number: 1724
Loss of IRF5 Ameliorates Tissue Fibrosis in a Murine Model of Systemic Sclerosis
-
Abstract Number: 1725
The SYK Inhibitor Fostamatinib Limits Tissue Damage and Fibrosis in a Bleomycin-Induced Scleroderma MOUSE MODEL
-
Abstract Number: 1726
Therapeutic Efficacy of Mesenchymal Stem Cells in Diffuse Murine Hypochlorite-Induced Systemic Sclerosis
-
Abstract Number: 1727
Poly(ADP-ribose) Polymerase-1 (PARP-1) Suppresses the Profibrotic Effects of Transforming Growth Factor â in Systemic Sclerosis
-
Abstract Number: 1728
Bromodomain Inhibitor JQ1 Modulates Collagen Processing and Ameliorates Bleomycin Induced Dermal Fibrosis in Mice
-
Abstract Number: 1729
Adenosine A2A Receptor (A2AR) Promotes Collagen Type 3 Expression Via β-Catenin Activation
-
Abstract Number: 1730
Identification of Novel Scleroderma –associated Antigens and Development of an Autoantibody Assay Panel Enabling Their Subsequent Validation